Regulation of neural responses to emotion perception by ketamine in individuals with treatment-resistant major depressive disorder

Translational Psychiatry

Volumn 5, Issue 2, 2015, Pages

  Murrough, J W ^a   Collins, K A ^a   Fields, J ^a   DeWilde, K E ^a   Phillips, M L ^b   Mathew, S J ^c,d   Wong, E ^a   Tang, C Y ^a   Charney, D S ^a   Iosifescu, D V ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; AMINO ACID RECEPTOR BLOCKING AGENT;

ADULT; ANTIDEPRESSANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG MECHANISM; EMOTION; FACIAL EXPRESSION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; MAJOR DEPRESSION; MALE; NERVE POTENTIAL; PERCEPTION; TREATMENT OUTCOME; TREATMENT RESISTANT DEPRESSION; TREATMENT RESISTANT MAJOR DEPRESSIVE DISORDER; TREATMENT RESPONSE; BRAIN; CASE CONTROL STUDY; CAUDATE NUCLEUS; DEPRESSIVE DISORDER, MAJOR; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; DRUG EFFECTS; MIDDLE AGED; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PATTERN RECOGNITION; YOUNG ADULT;

ADULT; BRAIN; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; DEPRESSIVE DISORDER, MAJOR; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; EMOTIONS; EXCITATORY AMINO ACID ANTAGONISTS; FACIAL EXPRESSION; FEMALE; FUNCTIONAL NEUROIMAGING; HUMANS; KETAMINE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; PATTERN RECOGNITION, VISUAL; SOCIAL PERCEPTION; YOUNG ADULT;

EID: 84927731898     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2015.10     Document Type: Article

References (64)

1. Collins PY, Patel V, Joestl SS, March D, Insel TR, Daar AS et al. Grand challenges in global mental health. Nature 2011; 475: 27-30.
2. Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR,D: implications for clinical practice. Am J Psychiatry 2006; 163: 28-40.
3. Trivedi MH, Fava M, Wisniewski SR, Thase ME, Quitkin F, Warden D et al. Medication augmentation after the failure of SSRIs for depression. N Engl J Med 2006; 354: 1243-1252.
4. Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000; 47: 351-354.
5. Zarate CA Jr, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 2006; 63: 856-864.
6. Mathew SJ, Murrough JW, Aanhet Rot M, Collins KA, Reich DL, Charney DS. Riluzole for relapse prevention following intravenous ketamine in treatmentresistant depression: a pilot randomized, placebo-controlled continuation trial. Int J Neuropsychopharmacol 2010; 13: 71-82.
7. Aanhet Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS et al. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression. Biol Psychiatry 2010; 67: 139-145.
8. Murrough JW, Perez AM, Pillemer S, Stern J, Parides MK, Aanhet Rot M et al. Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biol Psychiatry 2013; 74: 250-256.
9. Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM et al. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. Am J Psychiatry 2013; 170: 1134-1142.
10. Zarate CA Jr, Mathews DC, Furey ML. Human biomarkers of rapid antidepressant effects. Biol Psychiatry 2013; 73: 1142-1155.
11. Joormann J, Gotlib IH. Is this happiness I see Biases in the identification of emotional facial expressions in depression and social phobia. J Abnorm Psychol 2006; 115: 705-714.
12. Gotlib IH, Joormann J. Cognition and depression: current status and future directions. Annu Rev Clin Psychol 2010; 6: 285-312.
13. Diener C, Kuehner C, Brusniak W, Ubl B, Wessa M, Flor H. A meta-analysis of neurofunctional imaging studies of emotion and cognition in major depression. Neuroimage 2012; 61: 677-685.
14. Kupfer DJ, Frank E, Phillips ML. Major depressive disorder: new clinical, neurobiological, and treatment perspectives. Lancet 2012; 379: 1045-1055.
15. Murrough JW, Iacoviello B, Neumeister A, Charney DS, Iosifescu DV. Cognitive dysfunction in depression: neurocircuitry and new therapeutic strategies. Neurobiol Learn Mem 2011; 96: 553-563.
16. Surguladze SA, Young AW, Senior C, Brebion G, Travis MJ, Phillips ML. Recognition accuracy and response bias to happy and sad facial expressions in patients with major depression. Neuropsychology 2004; 18: 212-218.
17. Yoon KL, Joormann J, Gotlib IH. Judging the intensity of facial expressions of emotion: depression-related biases in the processing of positive affect. J Abnorm Psychol 2009; 118: 223-228.
18. Levens SM, Gotlib IH. Impaired selection of relevant positive information in depression. Depress Anxiety 2009; 26: 403-410.
19. Harmer CJ, O'Sullivan U, Favaron E, Massey-Chase R, Ayres R, Reinecke A et al. Effect of acute antidepressant administration on negative affective bias in depressed patients. Am J Psychiatry 2009; 166: 1178-1184.
20. Hamilton JP, Etkin A, Furman DJ, Lemus MG, Johnson RF, Gotlib IH. Functional neuroimaging of major depressive disorder: a meta-analysis and new integration of base line activation and neural response data. Am J Psychiatry 2012; 169: 693-703.
21. Groenewold NA, Opmeer EM, de Jonge P, Aleman A, Costafreda SG. Emotional valence modulates brain functional abnormalities in depression: evidence from a meta-analysis of fMRI studies. Neurosci Biobehav Rev 2013; 37: 152-163.
22. Fu CH, Williams SC, Cleare AJ, Brammer MJ, Walsh ND, Kim J et al. Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study. Arch Gen Psychiatry 2004; 61: 877-889.
23. Surguladze S, Brammer MJ, Keedwell P, Giampietro V, Young AW, Travis MJ et al. A differential pattern of neural response toward sad versus happy facial expressions in major depressive disorder. Biol Psychiatry 2005; 57: 201-209.
24. Keedwell PA, Andrew C, Williams SC, Brammer MJ, Phillips ML. The neural correlates of anhedonia in major depressive disorder. Biol Psychiatry 2005; 58: 843-853.
25. Epstein J, Pan H, Kocsis JH, Yang Y, Butler T, Chusid J et al. Lack of ventral striatal response to positive stimuli in depressed versus normal subjects. Am J Psychiatry 2006; 163: 1784-1790.
26. Pizzagalli DA, Holmes AJ, Dillon DG, Goetz EL, Birk JL, Bogdan R et al. Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder. Am J Psychiatry 2009; 166: 702-710.
27. Pizzagalli DA. Depression, stress, and anhedonia: toward a synthesis and integrated model. Annu Rev Clin Psychol 2014; 10: 393-423.
28. Delaveau P, Jabourian M, Lemogne C, Guionnet S, Bergouignan L, Fossati P. Brain effects of antidepressants in major depression: a meta-analysis of emotional processing studies. J Affect Disord 2011; 130: 66-74.
29. Ma Y. Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis. Mol Psychiatry 2015; e-pub ahead of print.
30. Sheline YI, Barch DM, Donnelly JM, Ollinger JM, Snyder AZ, Mintun MA. Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiatry 2001; 50: 651-658.
31. Fu CH, Williams SC, Brammer MJ, Suckling J, Kim J, Cleare AJ et al. Neural responses to happy facial expressions in major depression following antidepressant treatment. Am J Psychiatry 2007; 164: 599-607.
32. Simon GE, Perlis RH. Personalized medicine for depression: can we match patients with treatments Am J Psychiatry 2010; 167: 1445-1455.
33. Fu CH, Steiner H, Costafreda SG. Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies. Neurobiol Dis 2013; 52: 75-83.
34. Carlson PJ, Diazgranados N, Nugent AC, Ibrahim L, Luckenbaugh DA, Brutsche N et al. Neural correlates of rapid antidepressant response to ketamine in treatmentresistant unipolar depression: a preliminary positron emission tomography study. Biol Psychiatry 2013; 73: 1213-1221.
35. Nugent AC, Diazgranados N, Carlson PJ, Ibrahim L, Luckenbaugh DA, Brutsche N et al. Neural correlates of rapid antidepressant response to ketamine in bipolar disorder. Bipolar Disord 2014; 16: 119-128.
36. Fusar-Poli P, Placentino A, Carletti F, Landi P, Allen P, Surguladze S et al. Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies. J Psychiatry Neurosci 2009; 34: 418-432.
37. First MB Spitzer RL Gibbon M Williams JBW. Structured Clinical Interview for DSM-IV Axis Disorders (SCID). Biometrics Research, New York State Psychiatric Institute: New York, NY, USA, 1995.
38. Rush AJ, Gullion CM, Basco MR, Jarrett RB, Trivedi MH. The Inventory of Depressive Symptomatology (IDS): psychometric properties. Psychol Med 1996; 26: 477-486.
39. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134: 382-389.
40. Ekman P, Friesen WV. Pictures of Facial Affect. Consulting Psychologists Press: Palo Alto, CA, USA, 1976.
41. Young AW, Perret DI, Calder AJ, Sprengelmeyer R, Ekman P. Facial Expressions of Emotion: Stimuli and Tests (FEEST). Thames Valley Test Company: Bury St. Edmunds, UK, 2002.
42. Fitzgerald PB, Laird AR, Maller J, Daskalakis ZJ. A meta-analytic study of changes in brain activation in depression. Hum Brain Mapp 2008; 29: 683-695.
43. Wager TD, Phan KL, Liberzon I, Taylor SF. Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging. Neuroimage 2003; 19: 513-531.
44. Fusar-Poli P, Placentino A, Carletti F, Allen P, Landi P, Abbamonte M et al. Laterality effect on emotional faces processing: ALE meta-analysis of evidence. Neurosci Lett 2009; 452: 262-267.
45. Craig AD. How do you feel Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 2002; 3: 655-666.
46. Paulus MP, Stein MB. An insular view of anxiety. Biol Psychiatry 2006; 60: 383-387.
47. Mutschler I, Ball T, Wankerl J, Strigo IA. Pain and emotion in the insular cortex: evidence for functional reorganization in major depression. Neurosci Lett 2012; 520: 204-209.
48. Grant MM, Cannistraci C, Hollon SD, Gore J, Shelton R. Childhood trauma history differentiates amygdala response to sad faces within MDD. J Psychiatr Res 2011; 45: 886-895.
49. Moghaddam B, Adams B, Verma A, Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 1997; 17: 2921-2927.
50. Duman RS, Aghajanian GK. Synaptic dysfunction in depression: potential therapeutic targets. Science 2012; 338: 68-72.
51. Kegeles LS, Abi-Dargham A, Zea-Ponce Y, Rodenhiser-Hill J, Mann JJ, Van Heertum RL et al. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biol Psychiatry 2000; 48: 627-640.
52. Miller DW, Abercrombie ED. Effects of MK-801 on spontaneous and amphetamine-stimulated dopamine release in striatum measured with in vivo microdialysis in awake rats. Brain Res Bull 1996; 40: 57-62.
53. Rabiner EA. Imaging of striatal dopamine release elicited with NMDA antagonists: is there anything there to be seen J Psychopharmacol 2007; 21: 253-258.
54. Haber SN, Knutson B. The reward circuit: linking primate anatomy and human imaging. Neuropsychopharmacology 2010; 35: 4-26.
55. Watanabe K, Hikosaka O. Immediate changes in anticipatory activity of caudate neurons associated with reversal of position-reward contingency. J Neurophysiol 2005; 94: 1879-1887.
56. Balleine BW, Delgado MR, Hikosaka O. The role of the dorsal striatum in reward and decision-making. J Neurosci 2007; 27: 8161-8165.
57. Der-Avakian A, Markou A. The neurobiology of anhedonia and other rewardrelated deficits. Trends Neurosci 2012; 35: 68-77.
58. Liechti ME, Markou A. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats. Eur J Pharmacol 2007; 554: 164-174.
59. Faure A, Richard JM, Berridge KC. Desire and dread from the nucleus accumbens: cortical glutamate and subcortical GABA differentially generate motivation and hedonic impact in the rat. PLoS One 2010; 5: e11223.
60. Belujon P, Grace AA. Restoring mood balance in depression: ketamine reverses deficit in dopamine-dependent synaptic plasticity. Biol Psychiatry 2014; 76: 927-936.
61. Delgado MR, Nystrom LE, Fissell C, Noll DC, Fiez JA. Tracking the h emodynamic responses to reward and punishment in the striatum. J Neurophysiol 2000; 84: 3072-3077.
62. Elliott R, Friston KJ, Dolan RJ. Dissociable neural responses in human reward systems. J Neurosci 2000; 20: 6159-6165.
63. Ochsner KN, Hughes B, Robertson ER, Cooper JC, Gabrieli JD. Neural systems supporting the control of affective and cognitive conflicts. J Cogn Neurosci 2009; 21: 1842-1855.
64. Ochsner KN, Gross JJ. The cognitive control of emotion. Trends Cogn Sci 2005; 9: 242-249.