Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: A preliminary positron emission tomography study

Biological Psychiatry

Volumn 73, Issue 12, 2013, Pages 1213-1221

  Carlson, Paul J ^a   Diazgranados, Nancy ^b   Nugent, Allison C ^c   Ibrahim, Lobna ^c   Luckenbaugh, David A ^c   Brutsche, Nancy ^c   Herscovitch, Peter ^d   Manji, Husseini K ^e   Zarate Jr , Carlos A ^c   Drevets, Wayne C ^e,f  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^f University of Oklahoma Tulsa College of Medicine   (United States)

Author keywords

Habenula; insula; major depressive disorder; NMDA receptor antagonist; parahippocampal gyrus; PET imaging

Indexed keywords

KETAMINE;

ADULT; AGED; ANTIDEPRESSANT ACTIVITY; ARTICLE; BRAIN METABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HABENULA; HEMISPHERE; HUMAN; INFERIOR PARIETAL LOBULE; INSULA; MAJOR DEPRESSION; MALE; MIDDLE TEMPORAL GYRUS; MONTGOMERY ASBERG DEPRESSION RATING SCALE; OCCIPITAL CORTEX; PARAHIPPOCAMPAL GYRUS; PARIETAL CORTEX; PARIETOTEMPORAL CORTEX; PET SCANNER; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; REGION OF INTEREST; SENSORIMOTOR CORTEX; SINGLE DRUG DOSE; TREATMENT RESISTANT UNIPOLAR DEPRESSION; TREATMENT RESPONSE; VENTROLATERAL PREFRONTAL CORTEX; VOXEL BASED MORPHOMETRY;

ADULT; ANTIDEPRESSIVE AGENTS; BRAIN; BRAIN MAPPING; DEPRESSIVE DISORDER, TREATMENT-RESISTANT; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KETAMINE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; POSITRON-EMISSION TOMOGRAPHY;

EID: 84878394614     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.02.008     Document Type: Article

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