The neural correlates of anhedonia in major depressive disorder

Biological Psychiatry

Volumn 58, Issue 11, 2005, Pages 843-853

  Keedwell, Paul A ^a   Andrew, Chris ^a   Williams, Steven C R ^a   Brammer, Mick J ^a   Phillips, Mary L ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

fMRI; Major depression; Mood induction; Prefrontal cortex; Reward; Striatum

Indexed keywords

ADULT; ANHEDONIA; ARTICLE; CLINICAL ARTICLE; CORRELATION ANALYSIS; DISEASE SEVERITY; FACIAL EXPRESSION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HAPPINESS; HUMAN; MAJOR DEPRESSION; MALE; MOOD; NERVE POTENTIAL; OXYGEN BLOOD LEVEL; PRIORITY JOURNAL; STIMULUS RESPONSE;

ADULT; AFFECT; ANXIETY; BRAIN MAPPING; DEPRESSIVE DISORDER, MAJOR; ECHO-PLANAR IMAGING; FEMALE; HAPPINESS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MIDDLE AGED; NEOSTRIATUM; PSYCHIATRIC STATUS RATING SCALES; REWARD;

EID: 29044445558     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2005.05.019     Document Type: Article

References (46)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) 1994 American Psychiatric Association Washington DC
2. A.T. Beck Depression Clinical, Experimental and Theoretical Aspects 1967 Harper and Row New York
3. A.T. Beck, C.H. Ward, M. Mendelson, J. Mock, J. Erbaugh An inventory for measuring depression Arch Gen Psychiatry 4 1961 561 571
4. J.L. Beyer, K.R.R. Krishnan Volumetric brain imaging findings in mood disorders Bipolar Disorders 4 2002 89 104
5. A.J. Blood, R.J. Zatorre Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion Proceedings of the National Academy of Sciences of the United States of America 98 2001 11818 11823
6. M. Brammer, E.T. Bullmore, A. Simmons, S.C.R. Williams, P.M. Grasby, R.J. Howard Generic brain activation mapping in functional magnetic resonance imaging a nonparametric approach Magn Reson Imaging 15 1997 763 770
7. M. Breakspear, M.J. Brammer, P. Robinson Construction of multivariate surrogate sets from nonlinear data using the wavelet transform Physica D 182 2003 1 22
8. H.C. Breiter, R.L. Gollub, R.M. Weisskoff Acute effects of cocaine on human brain activity and emotion Neuron 19 1997 591 611
9. G.W. Brown, T.O. Harris The Social Origins of Depression 1978 Free Press London
10. E.T. Bullmore, C. Long, J. Suckling, J. Fadili, G.A. Calvert, F. Zelaya Coloured noise and computational inference in neurophysiological (fMRI) time series analysis resampling methods in time and wavelet domains Hum Brain Mapp 12 2001 61 78
11. E.T. Bullmore, J. Suckling, S. Overmeyer, S. Rabe-Hesketh, E. Taylor, M. Brammer Global, voxel and cluster tests, by theory and permutation, for a difference between two groups of structural MR images of the brain IEEE Trans Med Imaging 18 1999 32 34
12. D.M. Clark, J.D. Teasdale Diurnal variation in clinical depression and accessibility of memories of positive and negative experiences J Abnorm Psychol 91 2 1982 87 95
13. H.D. Critchley, R. Elliott, C.J. Mathias, R.J. Dolan Neural activity relating to generation and representation of galvanic skin conductance responses A functional magnetic resonance imaging study J Neuroscience 20 2000 3033 3040
14. W.C. Drevets, C. Gautier, J.C. Price, D.J. Kupfer, P.E. Kinahan, A.A. Grace Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria Biol Psychiatry 49 2001 81 96
15. R.T. Dunn, T.A. Kimbrell, T.A. Ketter, M.A. Frye, M.W. Willis, D.A. Luckenbaugh Principal components of the Beck Depression Inventory and regional cerebral metabolism in unipolar and bipolar depression Biol Psychiatry 51 2002 387 399
16. P. Ekman, W.V. Friesen Pictures of Facial Affect 1976 Consulting Psychologists Palo Alto
17. R. Elliott, K.J. Friston, R.J. Dolan Dissociable neural responses in human reward systems J Neuroscience 20 2000 6159 6165
18. R. Elliott, J.L. Newman, O.A. Longe, J.F. William Deakin Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems Neuroimage 21 2004 984 990
19. R. Elliott, J.S. Rubinsztein, B.J. Sahakian, R.J. Dolan The neural basis of mood-congruent processing biases in depression Arch Gen Psychiatry 59 2004 597 604
20. J. Fawcett, D.C. Clark, W.A. Schnefter, R.D. Gibson Assessing anhedonia in psychiatric patients The Pleasure Scale Arch Gen Psychiatry 40 1983 79 84
21. A.S. Garrett, R.J. Maddock Time course of the subjective emotional response to aversive pictures Relevance to fMRI studies Psychiatry Res Neuroimaging 108 1 2001 39 48
22. J.V. Haxby, E.A. Hoffman, M. Gobbini Human neural systems for face recognition and social communication Biol Psychiatry 51 1 2002 59 67
23. J.B. Henriques, R.J. Davidson Decreased responsiveness to reward in depression Cog and Emotion 14 2000 711 724
24. P.A. Keedwell, C. Andrew, S.C.R. Williams, M.J. Brammer, F. Zelaya, M.L. Phillips The neural Correlates of Depression (Abstract) Biol Psychiatry 53 2003 171S
25. Keedwell PA, Andrew C, Williams SCR, Brammer MJ, Zelaya F, Phillips ML (in press): A double dissociation of ventromedial prefrontal cortical responses to sad and happy stimuli in depressed and healthy individuals. Biol Psychiatry
26. D.F. Klein Endogenomorphic depression a conceptual and terminological revision Arch Gen Psychiatry 31 1974 447 454
27. B. Knutson, G.W. Fong, C.M. Adams, J.L. Varner, D. Hommer Dissociation of reward anticipation and outcome with event-related fMRI Neuroreport 12 17 2001 3683 3687
28. V. Kumari, M.T. Mitterschiffthaler, J.D. Teasdale, G.S. Malhi, R.G. Brown, V. Giampietro Neural Abnormalities during Cognitive Generation of Affect in Treatment-Resistant Depression Biol Psychiatry 54 2003 777 791
29. P.J. Lang, M.M. Bradley, B.N. Cuthbert International Affective Picture System (IAPS) Technical Manual and Affective Ratings 1997 NIMH Center for the Study of Emotion and Attention Gainesville, FL
30. M. Liotti, H.S. Mayberg, S. McGinnis, S.L. Brannan, P. Jerabek Unmasking disease-specific cerebral blood flow abnormalities mood challenge in patients with remitted unipolar depression Am J Psychiatry 159 2002 1830 1840 comment
31. G.G. Lloyd, W.A. Lishman Effect of depression on the speed of recall of pleasant and unpleasant experiences Psychol Med 5 2 1975 173 180
32. M.T. Mitterschiffthaler, V. Kumari, G.S. Malhi, R.G. Brown, V.P. Giampietro, M.J. Brammer Neural response to pleasant stimuli in anhedonia an fMRI study Neuroreport 14 2003 177 182
33. C.A. Naranjo, L.K. Tremblay, U.E. Busto The role of the brain reward system in depression Prog Neuro-Psychopharm & Biol Psychiatry 25 2001 781 823
34. J. O'Doherty, M.L. Kringelbach, E.T. Rolls, J. Hornak, C. Andrews Abstract reward and punishment representations in the human orbitofrontal cortex Nat Neurosci 4 1 2001 95 102
35. K.L. Phan, T. Wager, S.F. Taylor, I. Liberzon Functional Neuroanatomy of Emotion A meta-analysis of Emotion Activation Studies in PET and fMRI Neuroimage 16 2001 331 348
36. L. Rampello, N. Ferdinando, N. Francesco Dopamine and depression Therapeutic implications CNS Drugs 13 1 2000 33 45
37. H.A. Sackheim The definition and meaning of treatment resistant depression J Clin Psychiatry 62 Suppl 16 2001 1 17
38. F. Schneider, W. Grodd, U. Weiss, U. Klose, K.R. Mayer, T. Nagele Functional MRI reveals left amygdala activation during emotion Psychiatry Res 76 2-3 1997 75 82
39. C. Senior Beauty in the brain of the beholder Neuron 38 2004 525 528
40. D.M. Small, M.D. Gregory, Y.E. Mak, D. Gitelman, M.M. Mesulam, T. Parrish Dissociation of neural representation of intensity and affective valuation in human gustation Neuron 39 4 2003 701 711
41. A.P. Smith, R.N. Henson, R.J. Dolan, M.D. Rugg fMRI correlates of the episodic retrieval of emotional contexts Neuroimage 22 2004 868 878
42. P. Snaith Anhedonia a neglected symptom of psychopathology Psychol Medicine 23 1993 957 966
43. C.D. Spielberger State-Trait Anxiety Inventory for Adults 1983 Mind Garden California
44. S. Surguladze, P.A. Keedwell, M. Brammer, A. Young, C. Andrew, M. Travis A differential pattern of neural response and identification bias towards negative versus positive facial expressions in Major Depressive Disorder Biol Psychiatry 57 2005 201 209
45. J. Talairach, P. Tournoux Co-planar Stereotactic Atlas of the Human Brain 1998 Georg Thieme Verlag Stuttgart, Germany
46. World Health Organization ICD-10 Classification of Mental and Behavioural Disorders 1992 World Health Organization Geneva