메뉴 건너뛰기




Volumn 46, Issue 11, 2014, Pages

B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SODIUM IODIDE SYMPORTER; COTRANSPORTER; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1;

EID: 84927731232     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2014.68     Document Type: Article
Times cited : (34)

References (35)
  • 2
    • 84875361065 scopus 로고    scopus 로고
    • Molecular pathogenesis and mechanisms of thyroid cancer
    • Xing M. Molecular pathogenesis and mechanisms of thyroid cancer. Nat Rev Cancer 2013; 13: 184-199.
    • (2013) Nat Rev Cancer , vol.13 , pp. 184-199
    • Xing, M.1
  • 4
    • 0026690283 scopus 로고
    • Analysis of thyroid carcinoma based on material registered in Japan during 1977-1986 with special reference to predominance of papillary type
    • Ezaki H, Ebihara S, Fujimoto Y, Iida F, Ito K, Kuma K et al. Analysis of thyroid carcinoma based on material registered in Japan during 1977-1986 with special reference to predominance of papillary type. Cancer 1992; 70: 808-814.
    • (1992) Cancer , vol.70 , pp. 808-814
    • Ezaki, H.1    Ebihara, S.2    Fujimoto, Y.3    Iida, F.4    Ito, K.5    Kuma, K.6
  • 5
    • 0032709533 scopus 로고    scopus 로고
    • Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis
    • Ros P, Rossi DL, Acebron A, Santisteban P. Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis. Biochimie 1999; 81: 389-396.
    • (1999) Biochimie , vol.81 , pp. 389-396
    • Ros, P.1    Rossi, D.L.2    Acebron, A.3    Santisteban, P.4
  • 6
    • 0028123016 scopus 로고
    • Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms
    • Fabbro D, Di Loreto C, Beltrami CA, Belfiore A, Di Lauro R, Damante G. Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms. Cancer Res 1994; 54: 4744-4749.
    • (1994) Cancer Res , vol.54 , pp. 4744-4749
    • Fabbro, D.1    Di Loreto, C.2    Beltrami, C.A.3    Belfiore, A.4    Di Lauro, R.5    Damante, G.6
  • 7
    • 0026042003 scopus 로고
    • Human thyrotropin receptor gene: Expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation
    • Brabant G, Maenhaut C, Kohrle J, Scheumann G, Dralle H, Hoang-Vu C et al. Human thyrotropin receptor gene: Expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation. Mol Cell Endocrinol 1991; 82: R7-R12.
    • (1991) Mol Cell Endocrinol , vol.82 , pp. R7-R12
    • Brabant, G.1    Maenhaut, C.2    Kohrle, J.3    Scheumann, G.4    Dralle, H.5    Hoang-Vu, C.6
  • 8
    • 0026035268 scopus 로고
    • The mRNA levels of thyrotropin receptor, thyroglobulin and thyroid peroxidase in neoplastic human thyroid tissues
    • Ohta K, Endo T, Onaya T. The mRNA levels of thyrotropin receptor, thyroglobulin and thyroid peroxidase in neoplastic human thyroid tissues. Biochem Biophys Res Commun 1991; 174: 1148-1153.
    • (1991) Biochem Biophys Res Commun , vol.174 , pp. 1148-1153
    • Ohta, K.1    Endo, T.2    Onaya, T.3
  • 10
    • 78650976224 scopus 로고    scopus 로고
    • The BRAF mutation is predictive of aggressive clinicopathological characteristics in papillary thyroid microcarcinoma
    • Lin KL, Wang OC, Zhang XH, Dai XX, Hu XQ, Qu JM. The BRAF mutation is predictive of aggressive clinicopathological characteristics in papillary thyroid microcarcinoma. Ann Surg Oncol 2010; 17: 3294-3300.
    • (2010) Ann Surg Oncol , vol.17 , pp. 3294-3300
    • Lin, K.L.1    Wang, O.C.2    Zhang, X.H.3    Dai, X.X.4    Hu, X.Q.5    Qu, J.M.6
  • 11
    • 59449090715 scopus 로고    scopus 로고
    • Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma
    • Lee X, Gao M, Ji Y, Yu Y, Feng Y, Li Y et al. Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma. Ann Surg Oncol 2009; 16: 240-245.
    • (2009) Ann Surg Oncol , vol.16 , pp. 240-245
    • Lee, X.1    Gao, M.2    Ji, Y.3    Yu, Y.4    Feng, Y.5    Li, Y.6
  • 14
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • Xing M. BRAF mutation in thyroid cancer. Endocr Relat Cancer 2005; 12: 245-262.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 245-262
    • Xing, M.1
  • 15
  • 16
    • 45849106001 scopus 로고    scopus 로고
    • BRAFV600E mutation, but not RET/PTC rearrangements, is correlated with a lower expression of both thyroperoxidase and sodium iodide symporter genes in papillary thyroid cancer
    • Romei C, Ciampi R, Faviana P, Agate L, Molinaro E, Bottici V et al. BRAFV600E mutation, but not RET/PTC rearrangements, is correlated with a lower expression of both thyroperoxidase and sodium iodide symporter genes in papillary thyroid cancer. Endocr Relat Cancer 2008; 15: 511-520.
    • (2008) Endocr Relat Cancer , vol.15 , pp. 511-520
    • Romei, C.1    Ciampi, R.2    Faviana, P.3    Agate, L.4    Molinaro, E.5    Bottici, V.6
  • 17
    • 61449180326 scopus 로고    scopus 로고
    • Expression of iodine metabolism genes in human thyroid tissues: Evidence for age and BRAFV600E mutation dependency
    • Espadinha C, Santos JR, Sobrinho LG, Bugalho MJ. Expression of iodine metabolism genes in human thyroid tissues: Evidence for age and BRAFV600E mutation dependency. Clin Endocrinol (Oxf) 2009; 70: 629-635.
    • (2009) Clin Endocrinol (Oxf) , vol.70 , pp. 629-635
    • Espadinha, C.1    Santos, J.R.2    Sobrinho, L.G.3    Bugalho, M.J.4
  • 18
    • 33947290100 scopus 로고    scopus 로고
    • Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant
    • Liu D, Hu S, Hou P, Jiang D, Condouris S, Xing M. Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant. Clin Cancer Res 2007; 13: 1341-1349.
    • (2007) Clin Cancer Res , vol.13 , pp. 1341-1349
    • Liu, D.1    Hu, S.2    Hou, P.3    Jiang, D.4    Condouris, S.5    Xing, M.6
  • 19
    • 84055191090 scopus 로고    scopus 로고
    • Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation
    • Chakravarty D, Santos E, Ryder M, Knauf JA, Liao XH, West BL et al. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest 2011; 121: 4700-4711.
    • (2011) J Clin Invest , vol.121 , pp. 4700-4711
    • Chakravarty, D.1    Santos, E.2    Ryder, M.3    Knauf, J.A.4    Liao, X.H.5    West, B.L.6
  • 20
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases, and cancer
    • Robertson KD. DNA methylation, methyltransferases, and cancer. Oncogene 2001; 20: 3139-3155.
    • (2001) Oncogene , vol.20 , pp. 3139-3155
    • Robertson, K.D.1
  • 21
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006; 38: 787-793.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3    Young, J.4    Long, T.I.5    Faasse, M.A.6
  • 22
    • 33751549248 scopus 로고    scopus 로고
    • BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor kappaB activation
    • Palona I, Namba H, Mitsutake N, Starenki D, Podtcheko A, Sedliarou I et al. BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor kappaB activation. Endocrinology 2006; 147: 5699-5707.
    • (2006) Endocrinology , vol.147 , pp. 5699-5707
    • Palona, I.1    Namba, H.2    Mitsutake, N.3    Starenki, D.4    Podtcheko, A.5    Sedliarou, I.6
  • 23
    • 0037326161 scopus 로고    scopus 로고
    • The sodium/iodide symporter (NIS): Characterization, regulation, and medical significance
    • Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M et al. The sodium/iodide symporter (NIS): Characterization, regulation, and medical significance. Endocr Rev 2003; 24: 48-77.
    • (2003) Endocr Rev , vol.24 , pp. 48-77
    • Dohan, O.1    De La Vieja, A.2    Paroder, V.3    Riedel, C.4    Artani, M.5    Reed, M.6
  • 24
    • 84864467278 scopus 로고    scopus 로고
    • The sodium iodide symporter (NIS): Regulation and approaches to targeting for cancer therapeutics
    • Kogai T, Brent GA. The sodium iodide symporter (NIS): Regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther 2012; 135: 355-370.
    • (2012) Pharmacol Ther , vol.135 , pp. 355-370
    • Kogai, T.1    Brent, G.A.2
  • 25
    • 30944445020 scopus 로고    scopus 로고
    • BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: Functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis
    • Mitsutake N, Miyagishi M, Mitsutake S, Akeno N, Mesa C Jr, Knauf JA et al. BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: Functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis. Endocrinology 2006; 147: 1014-1019.
    • (2006) Endocrinology , vol.147 , pp. 1014-1019
    • Mitsutake, N.1    Miyagishi, M.2    Mitsutake, S.3    Akeno, N.4    Mesa, C.5    Knauf, J.A.6
  • 26
    • 33645964942 scopus 로고    scopus 로고
    • The oncogene BRAF V600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I- targeting to the membrane
    • Riesco-Eizaguirre G, Gutierrez-Martinez P, Garcia-Cabezas MA, Nistal M, Santisteban P. The oncogene BRAF V600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I- targeting to the membrane. Endocr Relat Cancer 2006; 13: 257-269.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 257-269
    • Riesco-Eizaguirre, G.1    Gutierrez-Martinez, P.2    Garcia-Cabezas, M.A.3    Nistal, M.4    Santisteban, P.5
  • 27
    • 70350554104 scopus 로고    scopus 로고
    • The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer
    • Riesco-Eizaguirre G, Rodriguez I, De la Vieja A, Costamagna E, Carrasco N, Nistal M et al. The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer. Cancer Res 2009; 69: 8317-8325.
    • (2009) Cancer Res , vol.69 , pp. 8317-8325
    • Riesco-Eizaguirre, G.1    Rodriguez, I.2    De La Vieja, A.3    Costamagna, E.4    Carrasco, N.5    Nistal, M.6
  • 28
    • 84872350060 scopus 로고    scopus 로고
    • Methylation levels of sodium-iodide symporter (NIS) promoter in benign and malignant thyroid tumors with reduced NIS expression
    • Galrao AL, Sodre AK, Camargo RY, Friguglietti CU, Kulcsar MA, Lima EU et al. Methylation levels of sodium-iodide symporter (NIS) promoter in benign and malignant thyroid tumors with reduced NIS expression. Endocrine 2013; 43: 225-229.
    • (2013) Endocrine , vol.43 , pp. 225-229
    • Galrao, A.L.1    Sodre, A.K.2    Camargo, R.Y.3    Friguglietti, C.U.4    Kulcsar, M.A.5    Lima, E.U.6
  • 29
    • 0033306106 scopus 로고    scopus 로고
    • Restoration of iodide uptake in dedifferentiated thyroid carcinoma: Relationship to human Na+/I-symporter gene methylation status
    • Venkataraman GM, Yatin M, Marcinek R, Ain KB. Restoration of iodide uptake in dedifferentiated thyroid carcinoma: Relationship to human Na+/I-symporter gene methylation status. J Clin Endocrinol Metab 1999; 84: 2449-2457.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2449-2457
    • Venkataraman, G.M.1    Yatin, M.2    Marcinek, R.3    Ain, K.B.4
  • 30
    • 35448983934 scopus 로고    scopus 로고
    • Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC
    • Provenzano MJ, Fitzgerald MP, Krager K, Domann FE. Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC). Otolaryngol Head Neck Surg 2007; 137: 722-728.
    • (2007) Otolaryngol Head Neck Surg , vol.137 , pp. 722-728
    • Provenzano, M.J.1    Fitzgerald, M.P.2    Krager, K.3    Domann, F.E.4
  • 31
    • 33947545622 scopus 로고    scopus 로고
    • Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor
    • Li W, Venkataraman GM, Ain KB. Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor. J Clin Endocrinol Metab 2007; 92: 1080-1087.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1080-1087
    • Li, W.1    Venkataraman, G.M.2    Ain, K.B.3
  • 33
    • 33745627069 scopus 로고    scopus 로고
    • DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas
    • Peng DF, Kanai Y, Sawada M, Ushijima S, Hiraoka N, Kitazawa S et al. DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas. Carcinogenesis 2006; 27: 1160-1168.
    • (2006) Carcinogenesis , vol.27 , pp. 1160-1168
    • Peng, D.F.1    Kanai, Y.2    Sawada, M.3    Ushijima, S.4    Hiraoka, N.5    Kitazawa, S.6
  • 34
    • 2342575723 scopus 로고    scopus 로고
    • RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells
    • Suzuki M, Sunaga N, Shames DS, Toyooka S, Gazdar AF, Minna JD. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells. Cancer Res 2004; 64: 3137-3143.
    • (2004) Cancer Res , vol.64 , pp. 3137-3143
    • Suzuki, M.1    Sunaga, N.2    Shames, D.S.3    Toyooka, S.4    Gazdar, A.F.5    Minna, J.D.6
  • 35
    • 41349103438 scopus 로고    scopus 로고
    • Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia
    • Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E et al. Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia. Blood 2008; 111: 2364-2373.
    • (2008) Blood , vol.111 , pp. 2364-2373
    • Liu, S.1    Liu, Z.2    Xie, Z.3    Pang, J.4    Yu, J.5    Lehmann, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.