Structure and function of neisseria gonorrhoeae MtrF illuminates a class of antimetabolite efflux pumps

Cell Reports

Volumn 11, Issue 1, 2015, Pages 61-70

  Su, Chih Chia ^a   Bolla, Jani Reddy ^a   Kumar, Nitin ^a   Radhakrishnan, Abhijith ^a   Long, Feng ^a   Delmar, Jared A ^a   Chou, Tsung Han ^a   Rajashankar, Kanagalaghatta R ^b   Shafer, William M ^c,d   Yu, Edward W ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b Argonne National Laboratory ^*  (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN MTRF; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; MTRR PROTEIN, NEISSERIA GONORRHOEAE; REPRESSOR PROTEIN; SULFONAMIDE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BILAYER MEMBRANE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYTOPLASM; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GONORRHEA; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR MODEL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); NEISSERIA GONORRHOEAE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GONORRHEA; HUMANS; MODELS, MOLECULAR; NEISSERIA GONORRHOEAE; PROTEIN CONFORMATION; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84927692255     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.03.003     Document Type: Article

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