Photoactivation of lysosomally sequestered sunitinib after angiostatic treatment causes vascular occlusion and enhances tumor growth inhibition

Cell Death and Disease

Volumn 6, Issue 2, 2015, Pages

  Nowak Sliwinska, P ^a   Weiss, A ^a,b   Van Beijnum, J R ^b   Wong, T J ^b   Kilarski, W W ^a   Szewczyk, G ^c   Verheul, H M W ^b   Sarna, T ^c   Van Den Bergh, H ^a   Griffioen, A W ^b  

^a EPFL   (Switzerland)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

SUNITINIB; INDOLE DERIVATIVE; PYRROLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD VESSEL OCCLUSION; CANCER INHIBITION; CELL DEATH; CELLS; CHORIOALLANTOIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIGHT EXPOSURE; LYSOSOME; MOUSE; NONHUMAN; OVARIAN CANCER CELL LINE; OVARY CARCINOMA; PHOTOACTIVATION; PRIORITY JOURNAL; TUMOR NECROSIS; ANIMAL; BAGG ALBINO MOUSE; CHICKEN; COLORECTAL NEOPLASMS; METABOLISM; OVARIAN NEOPLASMS; PHOTOTHERAPY; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL;

CITRUS MACROPHYLLA; MUS;

ANIMALS; CELL LINE, TUMOR; CHICKENS; COLORECTAL NEOPLASMS; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; LYSOSOMES; MICE; MICE, INBRED BALB C; OVARIAN NEOPLASMS; PHOTOTHERAPY; PYRROLES;

EID: 84927603549     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.4     Document Type: Article

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