Drug resistance to paclitaxel is not only associated with ABCB1 mRNA expression but also with drug accumulation in intracellular compartments in human lung cancer cell lines

International Journal of Oncology

Volumn 40, Issue 4, 2012, Pages 995-1004

  Shimomura, Masanori ^a,b   Yaoi, Takeshi ^b   Itoh, Kyoko ^b   Kato, Daishiro ^a   Terauchi, Kunihiko ^a   Shimada, Junichi ^a   Fushiki, Shinji ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Drug resistance; Intracellular localization; Lung cancer; Paclitaxel

Indexed keywords

BETA TUBULIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL;

ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL COMPARTMENTALIZATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CYTOPLASM; CYTOTOXICITY TEST; DNA SEQUENCE; DRUG ACCUMULATION; DRUG PROTEIN BINDING; DRUG TARGETING; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG CANCER; LYSOSOME; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ACETYLATION; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING SITES; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; HUMANS; LUNG NEOPLASMS; MICROSCOPY, CONFOCAL; P-GLYCOPROTEIN; PACLITAXEL; POINT MUTATION; RNA, MESSENGER; TUBULIN;

EID: 84858656289     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1297     Document Type: Article

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