메뉴 건너뛰기




Volumn 6, Issue 1, 2015, Pages

The common Chymotrypsinogen C (CTRC) variant G60G (C.180T) increases risk of chronic pancreatitis but not recurrent acute Pancreatitis in a North American population

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR; CARBOXYPEPTIDASE A; CHYMOTRYPSINOGEN; CHYMOTRYPSINOGEN C; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GAMMA GLUTAMYLTRANSFERASE; SERINE PROTEASE INHIBITOR KASAL TYPE 1; SERINE PROTEINASE INHIBITOR; TRYPSIN; UNCLASSIFIED DRUG;

EID: 84927603475     PISSN: 2155384X     EISSN: None     Source Type: Journal    
DOI: 10.1038/ctg.2014.13     Document Type: Article
Times cited : (63)

References (60)
  • 1
    • 50549086404 scopus 로고    scopus 로고
    • Multicenter approach to recurrent acute and chronic pancreatitis in the United States: The North American Pancreatitis Study 2 (NAPS2)
    • Whitcomb DC, Yadav D, Adam S et al. Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2). Pancreatology 2008; 8: 520-531.
    • (2008) Pancreatology , vol.8 , pp. 520-531
    • Whitcomb, D.C.1    Yadav, D.2    Adam, S.3
  • 2
    • 0035109764 scopus 로고    scopus 로고
    • Chronic pancreatitis: Diagnosis, classification, and new genetic developments
    • Etemad B, Whitcomb DC. Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 2001; 120: 682-707.
    • (2001) Gastroenterology , vol.120 , pp. 682-707
    • Etemad, B.1    Whitcomb, D.C.2
  • 3
    • 84874113455 scopus 로고    scopus 로고
    • Physical and mental quality of life in chronic pancreatitis: A case-control study from the North American Pancreatitis Study 2 Cohort
    • Amann ST, Yadav D, Barmada MM et al. Physical and mental quality of life in chronic pancreatitis: a case-control study from the North American Pancreatitis Study 2 Cohort. Pancreas 2013; 42: 293-300.
    • (2013) Pancreas , vol.42 , pp. 293-300
    • Amann, S.T.1    Yadav, D.2    Barmada, M.M.3
  • 4
    • 84876787550 scopus 로고    scopus 로고
    • The epidemiology of pancreatitis and pancreatic cancer
    • Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology 2013; 144: 1252-1261.
    • (2013) Gastroenterology , vol.144 , pp. 1252-1261
    • Yadav, D.1    Lowenfels, A.B.2
  • 5
    • 33646676272 scopus 로고    scopus 로고
    • Acute pancreatitis
    • Whitcomb DC. Acute pancreatitis. N Engl J Med 2006; 354: 2142-2150.
    • (2006) N Engl J Med , vol.354 , pp. 2142-2150
    • Whitcomb, D.C.1
  • 6
    • 84871172866 scopus 로고    scopus 로고
    • Classification of acute pancreatitis-2012: Revision of the Atlanta classification and definitions by international consensus
    • Banks PA, Bollen TL, Dervenis C et al. Classification of acute pancreatitis-2012: revision of the Atlanta classification and definitions by international consensus. Gut 2013; 62: 102-111.
    • (2013) Gut , vol.62 , pp. 102-111
    • Banks, P.A.1    Bollen, T.L.2    Dervenis, C.3
  • 7
    • 34247630083 scopus 로고    scopus 로고
    • AGA Institute technical review on acute pancreatitis
    • Forsmark CE, Baillie J. AGA Institute technical review on acute pancreatitis. Gastroenterology 2007; 132: 2022-2044.
    • (2007) Gastroenterology , vol.132 , pp. 2022-2044
    • Forsmark, C.E.1    Baillie, J.2
  • 8
    • 63849165803 scopus 로고    scopus 로고
    • Acute pancreatitis as a model of SIRS
    • Bhatia M. Acute pancreatitis as a model of SIRS. Front Biosci 2009; 14: 2042-2050.
    • (2009) Front Biosci , vol.14 , pp. 2042-2050
    • Bhatia, M.1
  • 9
    • 34247197621 scopus 로고    scopus 로고
    • Chronic pancreatitis: Challenges and advances in pathogenesis, genetics, diagnosis, and therapy
    • Witt H, Apte MV, Keim V et al. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology 2007; 132: 1557-1573.
    • (2007) Gastroenterology , vol.132 , pp. 1557-1573
    • Witt, H.1    Apte, M.V.2    Keim, V.3
  • 10
    • 33747588068 scopus 로고    scopus 로고
    • Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis
    • Bachem MG, Zhou Z, Zhou S et al. Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis. J Gastroenterol Hepatol 2006; 21 (Suppl 3): S92-S96.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. S92-S96
    • Bachem, M.G.1    Zhou, Z.2    Zhou, S.3
  • 11
    • 84859903220 scopus 로고    scopus 로고
    • Timing of cholecystectomy after mild biliary pancreatitis: A systematic review
    • van Baal MC, Besselink MG, Bakker OJ et al. Timing of cholecystectomy after mild biliary pancreatitis: a systematic review. Ann Surg 2012; 255: 860-866.
    • (2012) Ann Surg , vol.255 , pp. 860-866
    • Van Baal, M.C.1    Besselink, M.G.2    Bakker, O.J.3
  • 12
    • 84898736753 scopus 로고    scopus 로고
    • Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
    • Gurusamy KS, Nagendran M, Davidson BR. Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis. Cochrane Database Syst Rev 2013; 9: CD010326.
    • (2013) Cochrane Database Syst Rev , vol.9 , pp. CD010326
    • Gurusamy, K.S.1    Nagendran, M.2    Davidson, B.R.3
  • 13
    • 71849108804 scopus 로고    scopus 로고
    • Long-term prognosis of acute pancreatitis in Japan
    • Takeyama Y. Long-term prognosis of acute pancreatitis in Japan. Clin Gastroenterol Hepatol 2009; 7 (11 Suppl): S15-S17.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , Issue.11 , pp. S15-S17
    • Takeyama, Y.1
  • 14
    • 60449119926 scopus 로고    scopus 로고
    • The recurrence of acute alcohol-associated pancreatitis can be reduced: A randomized controlled trial
    • Nordback I, Pelli H, Lappalainen-Lehto R et al. The recurrence of acute alcohol-associated pancreatitis can be reduced: a randomized controlled trial. Gastroenterology 2009; 136: 848-855.
    • (2009) Gastroenterology , vol.136 , pp. 848-855
    • Nordback, I.1    Pelli, H.2    Lappalainen-Lehto, R.3
  • 15
    • 10144246566 scopus 로고    scopus 로고
    • Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene
    • Whitcomb DC, Gorry MC, Preston RA et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996; 14: 141-145.
    • (1996) Nat Genet , vol.14 , pp. 141-145
    • Whitcomb, D.C.1    Gorry, M.C.2    Preston, R.A.3
  • 16
    • 0030813082 scopus 로고    scopus 로고
    • Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis
    • Gorry MC, Gabbaizedeh D, Furey W et al. Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology 1997; 113: 1063-1068.
    • (1997) Gastroenterology , vol.113 , pp. 1063-1068
    • Gorry, M.C.1    Gabbaizedeh, D.2    Furey, W.3
  • 17
    • 0030890255 scopus 로고    scopus 로고
    • A clinically based classification system for alcoholic chronic pancreatitis: Summary of an international workshop on chronic pancreatitis [see comments]
    • Ammann RW. A clinically based classification system for alcoholic chronic pancreatitis: summary of an international workshop on chronic pancreatitis [see comments]. Pancreas 1997; 14: 215-221.
    • (1997) Pancreas , vol.14 , pp. 215-221
    • Ammann, R.W.1
  • 18
    • 72049105349 scopus 로고    scopus 로고
    • Natural history of acute pancreatitis: A long-term population-based study
    • quiz 2806
    • Lankisch PG, Breuer N, Bruns A et al. Natural history of acute pancreatitis: a long-term population-based study. Am J Gastroenterol 2009; 104: 2797-2805 quiz 2806.
    • (2009) Am J Gastroenterol , vol.104 , pp. 2797-2805
    • Lankisch, P.G.1    Breuer, N.2    Bruns, A.3
  • 19
    • 84863724208 scopus 로고    scopus 로고
    • Natural history following the first attack of acute pancreatitis
    • Yadav D, O'Connell M, Papachristou GI. Natural history following the first attack of acute pancreatitis. Am J Gastroenterol 2012; 107: 1096-1103.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1096-1103
    • Yadav, D.1    O'Connell, M.2    Papachristou, G.I.3
  • 20
    • 10744233747 scopus 로고    scopus 로고
    • Clinical and genetic characteristics of hereditary pancreatitis in Europe
    • Howes N, Lerch MM, Greenhalf W et al. Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol 2004; 2: 252-261.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 252-261
    • Howes, N.1    Lerch, M.M.2    Greenhalf, W.3
  • 21
    • 0032775422 scopus 로고    scopus 로고
    • Hereditary pancreatitis: New insights into acute and chronic pancreatitis
    • Whitcomb DC. Hereditary pancreatitis: new insights into acute and chronic pancreatitis. Gut 1999; 45: 317-322.
    • (1999) Gut , vol.45 , pp. 317-322
    • Whitcomb, D.C.1
  • 22
  • 23
    • 84876813879 scopus 로고    scopus 로고
    • Genetic risk factors for pancreatic disorders
    • Whitcomb DC. Genetic risk factors for pancreatic disorders. Gastroenterology 2013; 144: 1292-1302.
    • (2013) Gastroenterology , vol.144 , pp. 1292-1302
    • Whitcomb, D.C.1
  • 24
    • 79951726916 scopus 로고    scopus 로고
    • Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis
    • Cote GA, Yadav D, Slivka A et al. Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis. Clin Gastroenterol Hepatol 2010; 9: 266-273.
    • (2010) Clin Gastroenterol Hepatol , vol.9 , pp. 266-273
    • Cote, G.A.1    Yadav, D.2    Slivka, A.3
  • 25
    • 78349259644 scopus 로고    scopus 로고
    • Italian consensus guidelines for chronic pancreatitis
    • Frulloni L, Falconi M, Gabbrielli A et al. Italian consensus guidelines for chronic pancreatitis. Dig Liver Dis 2010; 42 ((Suppl 6)): S381-S406.
    • (2010) Dig Liver Dis , vol.42 , pp. S381-S406
    • Frulloni, L.1    Falconi, M.2    Gabbrielli, A.3
  • 26
    • 85027934895 scopus 로고    scopus 로고
    • The Spanish Pancreatic Club recommendations for the diagnosis and treatment of chronic pancreatitis: Part 1 (diagnosis)
    • Martinez J, Abad-Gonzalez A, Aparicio JR et al. The Spanish Pancreatic Club recommendations for the diagnosis and treatment of chronic pancreatitis: part 1 (diagnosis). Pancreatology 2013; 13: 8-17.
    • (2013) Pancreatology , vol.13 , pp. 8-17
    • Martinez, J.1    Abad-Gonzalez, A.2    Aparicio, J.R.3
  • 27
    • 84921815717 scopus 로고    scopus 로고
    • Chronic pancreatitis-definition, etiology, investigation and treatment
    • Mayerle J, Hoffmeister A, Werner J et al. Chronic pancreatitis-definition, etiology, investigation and treatment. Dtsch Arztebl Int 2013; 110: 387-393.
    • (2013) Dtsch Arztebl Int , vol.110 , pp. 387-393
    • Mayerle, J.1    Hoffmeister, A.2    Werner, J.3
  • 28
    • 84901854117 scopus 로고    scopus 로고
    • Belgian consensus on chronic pancreatitis in adults and children: Statements on diagnosis and nutritional, medical, and surgical treatment
    • Delhaye M, Van Steenbergen W, Cesmeli E et al. Belgian consensus on chronic pancreatitis in adults and children: statements on diagnosis and nutritional, medical, and surgical treatment. Acta Gastroenterol Belg 2014; 77: 47-65.
    • (2014) Acta Gastroenterol Belg , vol.77 , pp. 47-65
    • Delhaye, M.1    Van Steenbergen, W.2    Cesmeli, E.3
  • 29
    • 0021638331 scopus 로고
    • Classification of pancreatitis
    • Sarner M, Cotton PB. Classification of pancreatitis. Gut 1984; 25: 756-759.
    • (1984) Gut , vol.25 , pp. 756-759
    • Sarner, M.1    Cotton, P.B.2
  • 30
    • 11144237484 scopus 로고    scopus 로고
    • Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats
    • Deng X, Wang L, Elm MS et al. Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats. Am J Pathol 2005; 166: 93-106.
    • (2005) Am J Pathol , vol.166 , pp. 93-106
    • Deng, X.1    Wang, L.2    Elm, M.S.3
  • 31
    • 38349118284 scopus 로고    scopus 로고
    • A rat model reproducing key pathological responses of alcoholic chronic pancreatitis
    • Gukovsky I, Lugea A, Shahsahebi M et al. A rat model reproducing key pathological responses of alcoholic chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 2008; 294: G68-G79.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G68-G79
    • Gukovsky, I.1    Lugea, A.2    Shahsahebi, M.3
  • 32
    • 79955850900 scopus 로고    scopus 로고
    • Recent advances in the epidemiology of alcoholic pancreatitis
    • Yadav D. Recent advances in the epidemiology of alcoholic pancreatitis. Curr Gastroenterol Rep 2011; 13: 157-165.
    • (2011) Curr Gastroenterol Rep , vol.13 , pp. 157-165
    • Yadav, D.1
  • 33
    • 0032480346 scopus 로고    scopus 로고
    • Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis
    • Cohn JA, Friedman KJ, Noone PG et al. Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 1998; 339: 653-658.
    • (1998) N Engl J Med , vol.339 , pp. 653-658
    • Cohn, J.A.1    Friedman, K.J.2    Noone, P.G.3
  • 34
    • 0032480253 scopus 로고    scopus 로고
    • Mutations of the cystic fibrosis gene in patients with chronic pancreatitis
    • Sharer N, Schwarz M, Malone G et al. Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med 1998; 339: 645-652.
    • (1998) N Engl J Med , vol.339 , pp. 645-652
    • Sharer, N.1    Schwarz, M.2    Malone, G.3
  • 35
    • 0034039578 scopus 로고    scopus 로고
    • Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis
    • Witt H, Luck W, Hennies HC et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000; 25: 213-216.
    • (2000) Nat Genet , vol.25 , pp. 213-216
    • Witt, H.1    Luck, W.2    Hennies, H.C.3
  • 36
    • 0033857452 scopus 로고    scopus 로고
    • SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis
    • Pfutzer RH, Barmada MM, Brunskill AP et al. SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis. Gastroenterology 2000; 119: 615-623.
    • (2000) Gastroenterology , vol.119 , pp. 615-623
    • Pfutzer, R.H.1    Barmada, M.M.2    Brunskill, A.P.3
  • 37
    • 2442657876 scopus 로고    scopus 로고
    • A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations
    • Felderbauer P, Hoffmann P, Einwachter H et al. A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations. BMC Gastroenterol 2003; 3: 34.
    • (2003) BMC Gastroenterol , vol.3 , pp. 34
    • Felderbauer, P.1    Hoffmann, P.2    Einwachter, H.3
  • 38
    • 58049113219 scopus 로고    scopus 로고
    • Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population: Role of serine protease inhibitor Kazal 1type and alcohol
    • Muddana V, Lamb J, Greer JB et al. Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population: Role of serine protease inhibitor Kazal 1type and alcohol. World J Gastroenterol 2008; 14: 4486-4491.
    • (2008) World J Gastroenterol , vol.14 , pp. 4486-4491
    • Muddana, V.1    Lamb, J.2    Greer, J.B.3
  • 39
    • 84880074579 scopus 로고    scopus 로고
    • Variation in the gamma-glutamyltransferase 1 gene and risk of chronic pancreatitis
    • Brand H, Diergaarde B, O'Connell MR et al. Variation in the gamma-glutamyltransferase 1 gene and risk of chronic pancreatitis. Pancreas 2013; 42: 836-840.
    • (2013) Pancreas , vol.42 , pp. 836-840
    • Brand, H.1    Diergaarde, B.2    O'Connell, M.R.3
  • 40
    • 37549072225 scopus 로고    scopus 로고
    • Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis
    • Rosendahl J, Witt H, Szmola R et al. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet 2008; 40: 78-82.
    • (2008) Nat Genet , vol.40 , pp. 78-82
    • Rosendahl, J.1    Witt, H.2    Szmola, R.3
  • 41
    • 38949132672 scopus 로고    scopus 로고
    • Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis
    • Masson E, Chen JM, Scotet V et al. Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis. Hum Genet 2008; 123: 83-91.
    • (2008) Hum Genet , vol.123 , pp. 83-91
    • Masson, E.1    Chen, J.M.2    Scotet, V.3
  • 42
    • 84861092264 scopus 로고    scopus 로고
    • Genetics of pancreatitis: An update for clinicians and genetic counselors
    • Solomon S, Whitcomb DC. Genetics of pancreatitis: an update for clinicians and genetic counselors. Curr Gastroenterol Rep 2012; 14: 112-117.
    • (2012) Curr Gastroenterol Rep , vol.14 , pp. 112-117
    • Solomon, S.1    Whitcomb, D.C.2
  • 43
    • 84865518991 scopus 로고    scopus 로고
    • Genetics of alcoholic and nonalcoholic pancreatitis
    • Whitcomb DC. Genetics of alcoholic and nonalcoholic pancreatitis. Curr Opin Gastroenterol 2012; 28: 501-506.
    • (2012) Curr Opin Gastroenterol , vol.28 , pp. 501-506
    • Whitcomb, D.C.1
  • 44
    • 84865955920 scopus 로고    scopus 로고
    • Genetics and pathogenesis of chronic pancreatitis: The 2012 update
    • Chen JM, Ferec C. Genetics and pathogenesis of chronic pancreatitis: the 2012 update. Clin Res Hepatol Gastroenterol 2012; 36: 334-340.
    • (2012) Clin Res Hepatol Gastroenterol , vol.36 , pp. 334-340
    • Chen, J.M.1    Ferec, C.2
  • 45
    • 84870511045 scopus 로고    scopus 로고
    • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
    • Whitcomb DC, Larusch J, Krasinskas AM et al. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet 2012; 44: 1349-1354.
    • (2012) Nat Genet , vol.44 , pp. 1349-1354
    • Whitcomb, D.C.1    Larusch, J.2    Krasinskas, A.M.3
  • 46
    • 84885019350 scopus 로고    scopus 로고
    • Variants in CPA1 are strongly associated with early onset chronic pancreatitis
    • Witt H, Beer S, Rosendahl J et al. Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nat Genet 2013; 45: 1216-1220.
    • (2013) Nat Genet , vol.45 , pp. 1216-1220
    • Witt, H.1    Beer, S.2    Rosendahl, J.3
  • 47
    • 65449140633 scopus 로고    scopus 로고
    • Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan
    • Chang MC, Chang YT, Wei SC et al. Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan. Pancreatology 2009; 9: 287-292.
    • (2009) Pancreatology , vol.9 , pp. 287-292
    • Chang, M.C.1    Chang, Y.T.2    Wei, S.C.3
  • 48
    • 67651036609 scopus 로고    scopus 로고
    • Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants
    • Derikx MH, Szmola R, te Morsche RH et al. Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants. Eur J Gastroenterol Hepatol 2009; 21: 889-894.
    • (2009) Eur J Gastroenterol Hepatol , vol.21 , pp. 889-894
    • Derikx, M.H.1    Szmola, R.2    Te Morsche, R.H.3
  • 49
    • 34547437254 scopus 로고    scopus 로고
    • Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme y
    • Szmola R, Sahin-Toth M. Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y. Proc Natl Acad Sci USA 2007; 104: 11227-11232.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11227-11232
    • Szmola, R.1    Sahin-Toth, M.2
  • 50
    • 84885611335 scopus 로고    scopus 로고
    • Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk
    • Beer S, Zhou J, Szabo A et al. Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk. Gut 2012; 62: 1616-1624.
    • (2012) Gut , vol.62 , pp. 1616-1624
    • Beer, S.1    Zhou, J.2    Szabo, A.3
  • 51
    • 84870056923 scopus 로고    scopus 로고
    • Determinants of chymotrypsin C cleavage specificity in the calcium binding loop of human cationic trypsinogen
    • Szabo A, Sahin-Toth M. Determinants of chymotrypsin C cleavage specificity in the calcium binding loop of human cationic trypsinogen. FEBS J 2012; 279: 4283-4292.
    • (2012) FEBS J , vol.279 , pp. 4283-4292
    • Szabo, A.1    Sahin-Toth, M.2
  • 52
    • 67249158929 scopus 로고    scopus 로고
    • Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis
    • Yadav D, Hawes RH, Brand RE et al. Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis. Arch Intern Med 2009; 169: 1035-1045.
    • (2009) Arch Intern Med , vol.169 , pp. 1035-1045
    • Yadav, D.1    Hawes, R.H.2    Brand, R.E.3
  • 53
    • 58149394346 scopus 로고    scopus 로고
    • Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients
    • Kitahara K, Kawa S, Katsuyama Y et al. Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients. Dis Markers 2008; 25: 175-180.
    • (2008) Dis Markers , vol.25 , pp. 175-180
    • Kitahara, K.1    Kawa, S.2    Katsuyama, Y.3
  • 54
    • 84905483296 scopus 로고    scopus 로고
    • Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis
    • LaRusch J, Jung J, General IJ et al. Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis. PLoS Genet 2014; 10: e1004376.
    • (2014) PLoS Genet , vol.10 , pp. e1004376
    • Larusch, J.1    Jung, J.2    General, I.J.3
  • 55
    • 33644660022 scopus 로고    scopus 로고
    • Genetic polymorphisms in alcoholic pancreatitis
    • Whitcomb DC. Genetic polymorphisms in alcoholic pancreatitis. Dig Dis 2005; 23: 247-254.
    • (2005) Dig Dis , vol.23 , pp. 247-254
    • Whitcomb, D.C.1
  • 56
    • 84885676141 scopus 로고    scopus 로고
    • Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants
    • Paliwal S, Bhaskar S, Mani KR et al. Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants. Gut 2012; 62: 1602-1606.
    • (2012) Gut , vol.62 , pp. 1602-1606
    • Paliwal, S.1    Bhaskar, S.2    Mani, K.R.3
  • 57
    • 84874646479 scopus 로고    scopus 로고
    • Identification of novel missense CTRC variants in Japanese patients with chronic pancreatitis
    • Masamune A, Nakano E, Kume K et al. Identification of novel missense CTRC variants in Japanese patients with chronic pancreatitis. Gut 2013; 62: 653-654.
    • (2013) Gut , vol.62 , pp. 653-654
    • Masamune, A.1    Nakano, E.2    Kume, K.3
  • 58
    • 84874659320 scopus 로고    scopus 로고
    • CFTR SPINK1 CTRC and PRSS1 variants in chronic pancreatitis: Is the role of mutated CFTR overestimated?
    • Rosendahl J, Landt O, Bernadova J et al. CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? Gut 2013; 62: 582-592.
    • (2013) Gut , vol.62 , pp. 582-592
    • Rosendahl, J.1    Landt, O.2    Bernadova, J.3
  • 59
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
    • Database issue
    • Ward LD, Kellis M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res 2012; 40 (Database issue): D930-D934.
    • (2012) Nucleic Acids Res , vol.40 , pp. D930-D934
    • Ward, L.D.1    Kellis, M.2
  • 60
    • 77951934907 scopus 로고    scopus 로고
    • Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis
    • Sandoval J, Pereda J, Rodriguez JL et al. Ordered transcriptional factor recruitment and epigenetic regulation of tnf-alpha in necrotizing acute pancreatitis. Cell Mol Life Sci 2010; 67: 1687-1697.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1687-1697
    • Sandoval, J.1    Pereda, J.2    Rodriguez, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.