Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

Cell Death and Disease

Volumn 6, Issue 2, 2015, Pages

  Lee, W ^a   Johnson, J ^a   Gough, D J ^a   Donoghue, J ^a   Cagnone, G L M ^a   Vaghjiani, V ^a   Brown, K A ^a   Johns, T G ^a   St John, J C ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; ASCORBIC ACID; AZACITIDINE; DNA POLYMERASE; DNA POLYMERASE GAMMA A; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOCHONDRIAL DNA; RNA POLYMERASE II; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; POLG PROTEIN, HUMAN;

ARTICLE; ASTROCYTE; CANCER CELL; CELL DIFFERENTIATION; DNA DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; EXON; GENE DOSAGE; GENE EXPRESSION REGULATION; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; NEURAL STEM CELL; PRIORITY JOURNAL; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; COPY NUMBER VARIATION; DRUG EFFECTS; GENETICS; IMMUNOPRECIPITATION; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

MUS;

ASCORBIC ACID; AZACITIDINE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; HUMANS; IMMUNOPRECIPITATION; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84927599830     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.34     Document Type: Article

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