A shared genetic basis for self-limited delayed puberty and idiopathic hypogonadotropic hypogonadism

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 4, 2015, Pages E646-E654

  Zhu, Jia ^a   Choa, Ruth E Y ^a   Guo, Michael H ^b,c,d   Plummer, Lacey ^a   Buck, Cassandra ^a   Palmert, Mark R ^e,f   Hirschhorn, Joel N ^b,c,d   Seminara, Stephanie B ^a   Chan, Yee Ming ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DELAYED PUBERTY; FAMILY; FAMILY HISTORY; FEMALE; GENE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM; IL17RD GENE; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; PEDIGREE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TAC3 GENE; DNA MUTATIONAL ANALYSIS; GENETICS; HYPOGONADISM;

FGFR1 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; G PROTEIN COUPLED RECEPTOR; HEPARAN SULFATE 6-O-SULFOTRANSFERASE; KAL1 PROTEIN, HUMAN; NERVE PROTEIN; PROKR2 PROTEIN, HUMAN; RECEPTOR; SCLEROPROTEIN; SULFOTRANSFERASE; TACHYKININ; TACHYKININ RECEPTOR;

ADOLESCENT; DNA MUTATIONAL ANALYSIS; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; HYPOGONADISM; MALE; NERVE TISSUE PROTEINS; PEDIGREE; PUBERTY, DELAYED; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RECEPTORS, TACHYKININ; RETROSPECTIVE STUDIES; SULFOTRANSFERASES; TACHYKININS;

EID: 84927593500     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2015-1080     Document Type: Article

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