The role of gene defects underlying isolated hypogonadotropic hypogonadism in patients with constitutional delay of growth and puberty

Fertility and Sterility

Volumn 95, Issue 8, 2011, Pages 2756-2758

  Vaaralahti, Kirsi ^a,b   Wehkalampi, Karoliina ^b,c   Tommiska, Johanna ^a,b   Laitinen, Eeva Maria ^a,b   Dunkel, Leo ^d,e   Raivio, Taneli ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

constitutional delay of growth and puberty; FGFR1; GNRHR; TAC3; TACR3; timing of puberty

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; GONADORELIN RECEPTOR; NEUROKININ B; TACHYKININ; TACHYKININ RECEPTOR;

ADOLESCENT; ARTICLE; DELAYED PUBERTY; EXON; FEMALE; GENE DELETION; GENE MUTATION; GENETIC ASSOCIATION; HETEROZYGOSITY; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; INTRON; MAJOR CLINICAL STUDY; MALE; MICROPENIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; FINLAND; GENETIC PREDISPOSITION TO DISEASE; GROWTH DISORDERS; HUMANS; HYPOGONADISM; MALE; MUTATION; NEUROKININ B; PEDIGREE; PHENOTYPE; PUBERTY, DELAYED; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, LHRH; RECEPTORS, NEUROKININ-3; RISK ASSESSMENT; RISK FACTORS;

EID: 79959730664     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2010.12.059     Document Type: Article

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