The placental protein syncytin-1 impairs antiviral responses and exaggerates inflammatory responses to influenza

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Tolosa, Jorge M ^a   Parsons, Kristy S ^b   Hansbro, Philip M ^b   Smith, Roger ^a   Wark, Peter B ^b,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c JOHN HUNTER HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; PLACENTA PROTEIN; SYNCYTIN 1; UNCLASSIFIED DRUG; CYTOKINE; SYNCYTIN; VIRUS ENVELOPE PROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL POPULATION; CELL VIABILITY; CYTOKINE RELEASE; CYTOKINE RESPONSE; CYTOTOXICITY; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; NONHUMAN; OLIGOMERIZATION; PANDEMIC INFLUENZA; PREGNANT WOMAN; PROTEIN EXPRESSION; VIRUS STRAIN; ADOLESCENT; ADULT; DISEASE PREDISPOSITION; DRUG EFFECTS; GENE EXPRESSION REGULATION; HELPER CELL; IMMUNOLOGY; INFLAMMATION; INFLUENZA A VIRUS (H1N1); METABOLISM; MONOCYTE; PHYSIOLOGY; PLACENTA; PREGNANCY; SECRETION (PROCESS); VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; CYTOKINES; DENDRITIC CELLS; DISEASE SUSCEPTIBILITY; FEMALE; GENE EXPRESSION REGULATION; GENE PRODUCTS, ENV; HUMANS; INFLAMMATION; INFLUENZA A VIRUS, H1N1 SUBTYPE; MONOCYTES; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; T-LYMPHOCYTES, HELPER-INDUCER; YOUNG ADULT;

EID: 84927534581     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118629     Document Type: Article

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