메뉴 건너뛰기




Volumn 6, Issue FEB, 2015, Pages

Label-free SRM-based relative quantification of antibiotic resistance mechanisms in Pseudomonas aeruginosa clinical isolates

Author keywords

AmpC cephalosporinase; Carbapenem resistance; Cephalosporin resistance; Multidrug efflux system; OprD porin; Pseudomonas aeruginosa; RT qPCR; SRM

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BACTERIAL RNA; BETA LACTAMASE AMPC; CARBAPENEM; CEFEPIME; CEFTAZIDIME; CEPHALOSPORIN; CEPHALOSPORINASE; COMPLEMENTARY DNA; EFFLUX PUMP; EXTENDED SPECTRUM BETA LACTAMASE; IMIPENEM; MEROPENEM; MESSENGER RNA; MEXAB OPRM PUMP; MEXCD OPRJ PUMP; MEXEF OPRN PUMP; MEXXY PUMP; OPRD PORIN; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; UNCLASSIFIED DRUG;

EID: 84927520071     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00081     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0345466364 scopus 로고    scopus 로고
    • Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides
    • Aires, J. R., Köhler, T., Nikaido, H., and Plesiat, P. (1999). Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides. Antimicrob. Agents Chemother. 43, 2624-2628.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 2624-2628
    • Aires, J.R.1    Köhler, T.2    Nikaido, H.3    Plesiat, P.4
  • 3
    • 0024009542 scopus 로고
    • Pseudomonas aeruginosa bacteremia: univariate and multivariate analyses of factors influencing the prognosis in 133 episodes
    • Bisbe, J., Gatell, J. M., Puig, J., Mallolas, J., Martinez, J. A., Jimenez de Anta, M. T., et al. (1988). Pseudomonas aeruginosa bacteremia: univariate and multivariate analyses of factors influencing the prognosis in 133 episodes. Rev. Infect. Dis. 10, 629-635. doi: 10.1093/clinids/10.3.629.
    • (1988) Rev. Infect. Dis , vol.10 , pp. 629-635
    • Bisbe, J.1    Gatell, J.M.2    Puig, J.3    Mallolas, J.4    Martinez, J.A.5    Jimenez de Anta, M.T.6
  • 4
    • 79955530880 scopus 로고    scopus 로고
    • Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter study
    • Cabot, G., Ocampo-Sosa, A. A., Tubau, F., Macia, M. D., Rodriguez, C., Moya, B., et al. (2011). Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter study. Antimicrob. Agents Chemother. 55, 1906-1911. doi: 10.1128/AAC.01645-10.
    • (2011) Antimicrob. Agents Chemother , vol.55 , pp. 1906-1911
    • Cabot, G.1    Ocampo-Sosa, A.A.2    Tubau, F.3    Macia, M.D.4    Rodriguez, C.5    Moya, B.6
  • 5
    • 77954523086 scopus 로고    scopus 로고
    • Options and considerations when selecting a quantitative proteomics strategy
    • Domon, B., and Aebersold, R. (2010). Options and considerations when selecting a quantitative proteomics strategy. Nat. Biotechnol. 28, 710-721. doi: 10.1038/nbt.1661.
    • (2010) Nat. Biotechnol , vol.28 , pp. 710-721
    • Domon, B.1    Aebersold, R.2
  • 6
    • 33644862846 scopus 로고    scopus 로고
    • Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR
    • Dumas, J. L., van Delden, C., Perron, K., and Köhler, T. (2006). Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR. FEMS Microbiol. Lett. 254, 217-225. doi: 10.1111/j.1574-6968.2005.00008.x.
    • (2006) FEMS Microbiol. Lett , vol.254 , pp. 217-225
    • Dumas, J.L.1    van Delden, C.2    Perron, K.3    Köhler, T.4
  • 7
    • 77954513767 scopus 로고    scopus 로고
    • The pros and cons of peptide-centric proteomics
    • Duncan, M. W., Aebersold, R., and Caprioli, R. M. (2010). The pros and cons of peptide-centric proteomics. Nat. Biotechnol. 28, 659-664. doi: 10.1038/nbt0710-659.
    • (2010) Nat. Biotechnol , vol.28 , pp. 659-664
    • Duncan, M.W.1    Aebersold, R.2    Caprioli, R.M.3
  • 8
    • 40849119746 scopus 로고    scopus 로고
    • Current therapies for pseudomonas aeruginosa
    • Giamarellou, H., and Kanellakopoulou, K. (2008). Current therapies for pseudomonas aeruginosa. Crit. Care Clin. 24, 261-278. doi: 10.1016/j.ccc.2007.12.004.
    • (2008) Crit. Care Clin , vol.24 , pp. 261-278
    • Giamarellou, H.1    Kanellakopoulou, K.2
  • 9
    • 34948828022 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections
    • Hocquet, D., Berthelot, P., Roussel-Delvallez, M., Favre, R., Jeannot, K., Bajolet, O., et al. (2007a). Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections. Antimicrob. Agents Chemother. 51, 3531-3536. doi: 10.1128/AAC.00503-07.
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 3531-3536
    • Hocquet, D.1    Berthelot, P.2    Roussel-Delvallez, M.3    Favre, R.4    Jeannot, K.5    Bajolet, O.6
  • 10
    • 34247140270 scopus 로고    scopus 로고
    • MexAB-OprM-and MexXY-overproducing mutants are very prevalent among clinical strains of Pseudomonas aeruginosa with reduced susceptibility to ticarcillin
    • Hocquet, D., Roussel-Delvallez, M., Cavallo, J. D., and Plesiat, P. (2007b). MexAB-OprM-and MexXY-overproducing mutants are very prevalent among clinical strains of Pseudomonas aeruginosa with reduced susceptibility to ticarcillin. Antimicrob. Agents Chemother. 51, 1582-1583. doi: 10.1128/AAC.01334-06.
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 1582-1583
    • Hocquet, D.1    Roussel-Delvallez, M.2    Cavallo, J.D.3    Plesiat, P.4
  • 11
    • 0029154443 scopus 로고
    • Purification of a 54-kilodalton protein (OprJ) produced in NfxB mutants of Pseudomonas aeruginosa and production of a monoclonal antibody specific to OprJ
    • Hosaka, M., Gotoh, N., and Nishino, T. (1995). Purification of a 54-kilodalton protein (OprJ) produced in NfxB mutants of Pseudomonas aeruginosa and production of a monoclonal antibody specific to OprJ. Antimicrob. Agents Chemother. 39, 1731-1735. doi: 10.1128/AAC.39.8.1731.
    • (1995) Antimicrob. Agents Chemother , vol.39 , pp. 1731-1735
    • Hosaka, M.1    Gotoh, N.2    Nishino, T.3
  • 12
    • 0033999155 scopus 로고    scopus 로고
    • Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients
    • Jalal, S., Ciofu, O., Hoiby, N., Gotoh, N., and Wretlind, B. (2000). Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrob. Agents Chemother. 44, 710-712. doi: 10.1128/AAC.44.3.710-712.2000.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 710-712
    • Jalal, S.1    Ciofu, O.2    Hoiby, N.3    Gotoh, N.4    Wretlind, B.5
  • 13
    • 0344131941 scopus 로고    scopus 로고
    • Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa
    • Köhler, T., Epp, S. F., Curty, L. K., and Pechere, J. C. (1999). Characterization of MexT, the regulator of the MexE-MexF-OprN multidrug efflux system of Pseudomonas aeruginosa. J. Bacteriol. 181, 6300-6305.
    • (1999) J. Bacteriol , vol.181 , pp. 6300-6305
    • Köhler, T.1    Epp, S.F.2    Curty, L.K.3    Pechere, J.C.4
  • 14
    • 0031016991 scopus 로고    scopus 로고
    • Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa
    • Köhler, T., Michea-Hamzehpour, M., Henze, U., Gotoh, N., Curty, L. K., and Pechere, J. C. (1997). Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa. Mol. Microbiol. 23, 345-354. doi: 10.1046/j.1365-2958.1997.2281594.x.
    • (1997) Mol. Microbiol , vol.23 , pp. 345-354
    • Köhler, T.1    Michea-Hamzehpour, M.2    Henze, U.3    Gotoh, N.4    Curty, L.K.5    Pechere, J.C.6
  • 15
    • 54049090766 scopus 로고    scopus 로고
    • Selected reaction monitoring for quantitative proteomics: a tutorial
    • Lange, V., Picotti, P., Domon, B., and Aebersold, R. (2008). Selected reaction monitoring for quantitative proteomics: a tutorial. Mol. Syst. Biol. 4, 222. doi: 10.1038/msb.2008.61.
    • (2008) Mol. Syst. Biol , vol.4 , pp. 222
    • Lange, V.1    Picotti, P.2    Domon, B.3    Aebersold, R.4
  • 16
    • 70449124604 scopus 로고    scopus 로고
    • Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms
    • Lister, P. D., Wolter, D. J., and Hanson, N. D. (2009). Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin. Microbiol. Rev. 22, 582-610. doi: 10.1128/CMR.00040-09.
    • (2009) Clin. Microbiol. Rev , vol.22 , pp. 582-610
    • Lister, P.D.1    Wolter, D.J.2    Hanson, N.D.3
  • 17
    • 0028883511 scopus 로고
    • beta-Lactamases in laboratory and clinical resistance
    • Livermore, D. M. (1995). beta-Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8, 557-584.
    • (1995) Clin. Microbiol. Rev , vol.8 , pp. 557-584
    • Livermore, D.M.1
  • 18
    • 0036498656 scopus 로고    scopus 로고
    • Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?
    • Livermore, D. M. (2002). Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin. Infect. Dis. 34, 634-640. doi: 10.1086/338782.
    • (2002) Clin. Infect. Dis , vol.34 , pp. 634-640
    • Livermore, D.M.1
  • 19
    • 0033847562 scopus 로고    scopus 로고
    • Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist
    • Lyczak, J. B., Cannon, C. L., and Pier, G. B. (2000). Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes. Infect. 2, 1051-1060. doi: 10.1016/S1286-4579(00)01259-4.
    • (2000) Microbes. Infect , vol.2 , pp. 1051-1060
    • Lyczak, J.B.1    Cannon, C.L.2    Pier, G.B.3
  • 20
    • 77951965920 scopus 로고    scopus 로고
    • Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
    • Maclean, B., Tomazela, D. M., Shulman, N., Chambers, M., Finney, G. L., Frewen, B., et al. (2010). Skyline: an open source document editor for creating and analyzing targeted proteomics experiments. Bioinformatics 26, 966-968. doi: 10.1093/bioinformatics/btq054.
    • (2010) Bioinformatics , vol.26 , pp. 966-968
    • Maclean, B.1    Tomazela, D.M.2    Shulman, N.3    Chambers, M.4    Finney, G.L.5    Frewen, B.6
  • 21
    • 84896987890 scopus 로고    scopus 로고
    • Overexpression of MexCD-OprJ reduces Pseudomonas aeruginosa virulence by increasing its susceptibility to complement-mediated killing
    • Martinez-Ramos, I., Mulet, X., Moya, B., Barbier, M., Oliver, A., and Alberti, S. (2014). Overexpression of MexCD-OprJ reduces Pseudomonas aeruginosa virulence by increasing its susceptibility to complement-mediated killing. Antimicrob. Agents Chemother. 58, 2426-2429. doi: 10.1128/AAC.02012-13.
    • (2014) Antimicrob. Agents Chemother , vol.58 , pp. 2426-2429
    • Martinez-Ramos, I.1    Mulet, X.2    Moya, B.3    Barbier, M.4    Oliver, A.5    Alberti, S.6
  • 22
    • 0034426126 scopus 로고    scopus 로고
    • Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa
    • Masuda, N., Sakagawa, E., Ohya, S., Gotoh, N., Tsujimoto, H., and Nishino, T. (2000). Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 44, 3322-3327. doi: 10.1128/AAC.44.12.3322-3327.2000.
    • (2000) Antimicrob. Agents Chemother , vol.44 , pp. 3322-3327
    • Masuda, N.1    Sakagawa, E.2    Ohya, S.3    Gotoh, N.4    Tsujimoto, H.5    Nishino, T.6
  • 23
    • 84865718193 scopus 로고    scopus 로고
    • Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses
    • McAlister, G. C., Huttlin, E. L., Haas, W., Ting, L., Jedrychowski, M. P., Rogers, J. C., et al. (2012). Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. Anal. Chem. 84, 7469-7478. doi: 10.1021/ac301572t.
    • (2012) Anal. Chem , vol.84 , pp. 7469-7478
    • McAlister, G.C.1    Huttlin, E.L.2    Haas, W.3    Ting, L.4    Jedrychowski, M.P.5    Rogers, J.C.6
  • 24
    • 16244414846 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa bloodstream infection: importance of appropriate initial antimicrobial treatment
    • Micek, S. T., Lloyd, A. E., Ritchie, D. J., Reichley, R. M., Fraser, V. J., and Kollef, M. H. (2005). Pseudomonas aeruginosa bloodstream infection: importance of appropriate initial antimicrobial treatment. Antimicrob. Agents Chemother. 49, 1306-1311. doi: 10.1128/AAC.49.4.1306-1311.2005.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 1306-1311
    • Micek, S.T.1    Lloyd, A.E.2    Ritchie, D.J.3    Reichley, R.M.4    Fraser, V.J.5    Kollef, M.H.6
  • 25
    • 0032994954 scopus 로고    scopus 로고
    • Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa
    • Mine, T., Morita, Y., Kataoka, A., Mizushima, T., and Tsuchiya, T. (1999). Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 43, 415-417.
    • (1999) Antimicrob. Agents Chemother , vol.43 , pp. 415-417
    • Mine, T.1    Morita, Y.2    Kataoka, A.3    Mizushima, T.4    Tsuchiya, T.5
  • 26
    • 84875898775 scopus 로고    scopus 로고
    • MexXY multidrug efflux system of Pseudomonas aeruginosa
    • Morita, Y., Tomida, J., and Kawamura, Y. (2012). MexXY multidrug efflux system of Pseudomonas aeruginosa. Front. Microbiol. 3:408. doi: 10.3389/fmicb.2012.00408.
    • (2012) Front. Microbiol , vol.3 , pp. 408
    • Morita, Y.1    Tomida, J.2    Kawamura, Y.3
  • 27
    • 2142761564 scopus 로고    scopus 로고
    • The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia
    • Mueller-Ortiz, S. L., Drouin, S. M., and Wetsel, R. A. (2004). The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia. Infect. Immun. 72, 2899-2906. doi: 10.1128/IAI.72.5.2899-2906.2004.
    • (2004) Infect. Immun , vol.72 , pp. 2899-2906
    • Mueller-Ortiz, S.L.1    Drouin, S.M.2    Wetsel, R.A.3
  • 28
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl, M. W., Horgan, G. W., and Dempfle, L. (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30:e36. doi: 10.1093/nar/30.9.e36.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 29
    • 68749094119 scopus 로고    scopus 로고
    • Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics
    • Picotti, P., Bodenmiller, B., Mueller, L. N., Domon, B., and Aebersold, R. (2009). Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell 138, 795-806. doi: 10.1016/j.cell.2009.05.051.
    • (2009) Cell , vol.138 , pp. 795-806
    • Picotti, P.1    Bodenmiller, B.2    Mueller, L.N.3    Domon, B.4    Aebersold, R.5
  • 30
    • 0036943824 scopus 로고    scopus 로고
    • Analysis of the Pseudomonas aeruginosa oprD gene from clinical and environmental isolates
    • Pirnay, J. P., De Vos, D., Mossialos, D., Vanderkelen, A., Cornelis, P., and Zizi, M. (2002). Analysis of the Pseudomonas aeruginosa oprD gene from clinical and environmental isolates. Environ. Microbiol. 4, 872-882. doi: 10.1046/j.1462-2920.2002.00281.x.
    • (2002) Environ. Microbiol , vol.4 , pp. 872-882
    • Pirnay, J.P.1    De Vos, D.2    Mossialos, D.3    Vanderkelen, A.4    Cornelis, P.5    Zizi, M.6
  • 31
    • 84857660045 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa: resistance to the max
    • Poole, K. (2011). Pseudomonas aeruginosa: resistance to the max. Front. Microbiol. 2:65. doi: 10.3389/fmicb.2011.00065.
    • (2011) Front. Microbiol , vol.2 , pp. 65
    • Poole, K.1
  • 32
    • 0242648332 scopus 로고    scopus 로고
    • Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa
    • Poole, K., Gotoh, N., Tsujimoto, H., Zhao, Q., Wada, A., Yamasaki, T., et al. (1996). Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa. Mol. Microbiol. 21, 713-724. doi: 10.1046/j.1365-2958.1996.281397.x.
    • (1996) Mol. Microbiol , vol.21 , pp. 713-724
    • Poole, K.1    Gotoh, N.2    Tsujimoto, H.3    Zhao, Q.4    Wada, A.5    Yamasaki, T.6
  • 33
    • 0027494050 scopus 로고
    • Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon
    • Poole, K., Krebes, K., McNally, C., and Neshat, S. (1993). Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon. J. Bacteriol. 175, 7363-7372.
    • (1993) J. Bacteriol , vol.175 , pp. 7363-7372
    • Poole, K.1    Krebes, K.2    McNally, C.3    Neshat, S.4
  • 34
    • 77954645140 scopus 로고    scopus 로고
    • Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts
    • Rau, M. H., Hansen, S. K., Johansen, H. K., Thomsen, L. E., Workman, C. T., Nielsen, K. F., et al. (2010). Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts. Environ. Microbiol. 12, 1643-1658.
    • (2010) Environ. Microbiol , vol.12 , pp. 1643-1658
    • Rau, M.H.1    Hansen, S.K.2    Johansen, H.K.3    Thomsen, L.E.4    Workman, C.T.5    Nielsen, K.F.6
  • 35
    • 64549150047 scopus 로고    scopus 로고
    • Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data
    • Ruijter, J. M., Ramakers, C., Hoogaars, W. M., Karlen, Y., Bakker, O., van den Hoff, M. J., et al. (2009). Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data. Nucleic Acids Res. 37:e45. doi: 10.1093/nar/gkp045.
    • (2009) Nucleic Acids Res , vol.37
    • Ruijter, J.M.1    Ramakers, C.2    Hoogaars, W.M.3    Karlen, Y.4    Bakker, O.5    van den Hoff, M.J.6
  • 36
    • 34848889259 scopus 로고    scopus 로고
    • The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra
    • Shilov, I. V., Seymour, S. L., Patel, A. A., Loboda, A., Tang, W. H., Keating, S. P., et al. (2007). The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra. Mol. Cell Proteomics 6, 1638-1655. doi: 10.1074/mcp.T600050-MCP200.
    • (2007) Mol. Cell Proteomics , vol.6 , pp. 1638-1655
    • Shilov, I.V.1    Seymour, S.L.2    Patel, A.A.3    Loboda, A.4    Tang, W.H.5    Keating, S.P.6
  • 37
    • 76149142168 scopus 로고    scopus 로고
    • Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry
    • Tabb, D. L., Vega-Montoto, L., Rudnick, P. A., Variyath, A. M., Ham, A. J., Bunk, D. M., et al. (2010). Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry. J. Proteome. Res. 9, 761-776. doi: 10.1021/pr9006365.
    • (2010) J. Proteome. Res , vol.9 , pp. 761-776
    • Tabb, D.L.1    Vega-Montoto, L.2    Rudnick, P.A.3    Variyath, A.M.4    Ham, A.J.5    Bunk, D.M.6
  • 38
    • 84949116813 scopus 로고    scopus 로고
    • Quantitative proteomics to study carbapenem resistance in Acinetobacter baumannii
    • Tiwari, V., and Tiwari, M. (2014). Quantitative proteomics to study carbapenem resistance in Acinetobacter baumannii. Front. Microbiol. 5:512. doi: 10.3389/fmicb.2014.00512.
    • (2014) Front. Microbiol , vol.5 , pp. 512
    • Tiwari, V.1    Tiwari, M.2
  • 39
    • 0025186624 scopus 로고
    • Outer membrane protein D2 catalyzes facilitated diffusion of carbapenems and penems through the outer membrane of Pseudomonas aeruginosa
    • Trias, J., and Nikaido, H. (1990a). Outer membrane protein D2 catalyzes facilitated diffusion of carbapenems and penems through the outer membrane of Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 34, 52-57.
    • (1990) Antimicrob. Agents Chemother , vol.34 , pp. 52-57
    • Trias, J.1    Nikaido, H.2
  • 40
    • 0025146217 scopus 로고
    • Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides
    • Trias, J., and Nikaido, H. (1990b). Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides. J. Biol. Chem. 265, 15680-15684.
    • (1990) J. Biol. Chem , vol.265 , pp. 15680-15684
    • Trias, J.1    Nikaido, H.2
  • 42
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele, J., De, P. K., Pattyn, F., Poppe, B., Van Roy, N., De, P. A., et al. (2002). Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3:34. doi: 10.1186/gb-2002-3-7-research0034.
    • (2002) Genome Biol , vol.3 , pp. 34
    • Vandesompele, J.1    De, P.K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De, P.A.6
  • 43
    • 2142697190 scopus 로고    scopus 로고
    • Role of the multidrug efflux system MexXY in the emergence of moderate resistance to aminoglycosides among Pseudomonas aeruginosa isolates from patients with cystic fibrosis
    • Vogne, C., Aires, J. R., Bailly, C., Hocquet, D., and Plesiat, P. (2004). Role of the multidrug efflux system MexXY in the emergence of moderate resistance to aminoglycosides among Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob. Agents Chemother. 48, 1676-1680. doi: 10.1128/AAC.48.5.1676-1680.2004.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 1676-1680
    • Vogne, C.1    Aires, J.R.2    Bailly, C.3    Hocquet, D.4    Plesiat, P.5
  • 44
    • 77949658199 scopus 로고    scopus 로고
    • Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals
    • Wang, J., Zhou, J. Y., Qu, T. T., Shen, P., Wei, Z. Q., Yu, Y. S., et al. (2010). Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Chinese hospitals. Int. J. Antimicrob. Agents 35, 486-491. doi: 10.1016/j.ijantimicag.2009.12.014.
    • (2010) Int. J. Antimicrob. Agents , vol.35 , pp. 486-491
    • Wang, J.1    Zhou, J.Y.2    Qu, T.T.3    Shen, P.4    Wei, Z.Q.5    Yu, Y.S.6
  • 45
    • 84921748614 scopus 로고    scopus 로고
    • Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome
    • Worboys, J. D., Sinclair, J., Yuan, Y., and Jorgensen, C. (2014). Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome. Nat. Methods 11, 1041-1044. doi: 10.1038/nmeth.3072.
    • (2014) Nat. Methods , vol.11 , pp. 1041-1044
    • Worboys, J.D.1    Sinclair, J.2    Yuan, Y.3    Jorgensen, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.