Anti-tumor efficacy of lidamycin in combination with chemotherapeutic drugs

Chinese Journal of New Drugs

Volumn 18, Issue 21, 2009, Pages 2075-2080

  Shang, Bo Yang ^a   Wu, Shu Ying ^a   Shang, Yue ^a   Li, Dian Dong ^a   Zhen, Yong Su ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

Anti tumor; Enediyne; Lidamycin; Synergetic effect

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; FLUOROURACIL; LIDAMYCIN; NAVELBINE; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CLONOGENIC ASSAY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN;

EID: 79952835149     PISSN: 10033734     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. ZHEN YS, MING XY, YU B, et al. A new macromoleculer antitumor antibiotic, C-1027 III. Antitumor activity[J]. J Antibiot, 1989,42(8):1294-1298.
2. Xu YJ, Li DD, Zhen YS. Mode of action of C-1027, a new macromolecular antitumor antibiotic with highly potent cytotoxicity, on human hepatoma BE-7402 cells[J]. Cancer Chemother Pharmacol, 1990,27(1):41-46.
3. GASPARINI G. Metronomic scheduling: the future of chemotherapy[J]. Lancet Oncol, 2001,2(12):733-740.
4. TURCHI JJ, HENKELS K. Human Ku autoantigen binds cisplatin-damaged DNA but fails to stimulate human DNA-activated protein kinase[J]. J Biol Chem, 1996,271(23):13861-13867.
5. HENKELS KM, TURCHI JJ. Induction of apoptosis in cisplatin-sensitive and - resistant human ovarian cancer cell lines[J]. Cancer Res, 1997,57(20):4488- 4492.
6. CHEN LH, JIANG JM, CHENG CL, et al. P53 dependent and independent apoptosis induced by lidamycin in human colorectal cancer cells[J]. Cancer Biol Ther, 2007,6(6):965-973.