ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer

Oncotarget

Volumn 6, Issue 9, 2015, Pages 6959-6976

  Chen, Ke ^a   Yu, Gan ^a   Gumireddy, Kiranmai ^b   Li, Anping ^b   Yao, Weimin ^a   Gao, Lu ^a   Chen, Shuliang ^c   Hao, Jun ^c   Wang, Ji ^d   Huang, Qihong ^b   Xu, Hua ^a   Ye, Zhangqun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WISTAR INSTITUTE   (United States)

^c WUHAN UNIVERSITY   (China)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

p300; Renal cancer; Tumor suppressor; VHL; ZBRK1

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; HYPOXIA INDUCIBLE FACTOR; SHORT HAIRPIN RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN; ZBRK1 PROTEIN; EP300 PROTEIN, HUMAN; PROTEIN BINDING; REPRESSOR PROTEIN; VHL PROTEIN, HUMAN; ZNF350 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER GROWTH; CARCINOGENESIS; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CANCER; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VON HIPPEL LINDAU GENE; ANIMAL; CELL MOTION; DISEASE COURSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; KIDNEY CARCINOMA; KIDNEY TUMOR; METABOLISM; NUDE MOUSE; PROGNOSIS; TUMOR INVASION; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOMA, RENAL CELL; CELL MOVEMENT; DISEASE PROGRESSION; E1A-ASSOCIATED P300 PROTEIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; KIDNEY NEOPLASMS; MICE, NUDE; NEOPLASM INVASIVENESS; PROGNOSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84927142812     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3134     Document Type: Article

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