Molecular and functional imaging of internet addiction

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Zhu, Yunqi ^a,b,c   Zhang, Hong ^a,b,c   Tian, Mei ^a,b,c  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c Key Laboratory of Medical Molecular Imaging of Zhejiang Province   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE;

BEHAVIOR; BRAIN; BRAIN METABOLISM; COGNITION; DOPAMINERGIC SYSTEM; FRONTAL CORTEX; HUMAN; INTERNET ADDICTION; MOLECULAR IMAGING; NEUROBIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; BEHAVIOR, ADDICTIVE; INTERNET; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIOGRAPHY;

BEHAVIOR, ADDICTIVE; BRAIN; COGNITION; DOPAMINE; HUMANS; INTERNET; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84927139001     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/378675     Document Type: Review

References (86)

1. A. I. Leshner,"Addiction is a brain disease, and it matters," Science, vol. 278, no. 5335, pp. 45-47, 1997.
2. T. E. Robinson and K. C. Berridge,"Addiction," Annual Review of Psychology, vol. 54, pp. 25-53, 2003.
3. D. Sulzer,"How addictive drugs disrupt presynaptic dopamine neurotransmission," Neuron, vol. 69, no. 4, pp. 628-649, 2011.
4. N. M. Petry, F. Rehbein, D. A. Gentile et al.,"An international consensus for assessing internet gaming disorder using the new DSM-5 approach," Addiction, vol. 109, no. 9, pp. 1399-1406, 2014.
5. D. J. Kuss,"Internet gaming addiction: current perspectives," Psychology Research and Behavior Management, vol. 6, pp. 125-137, 2013.
6. D. E. Greydanus and M. M. Greydanus,"Internet use, misuse, and addiction in adolescents: current issues and challenges," International Journal of AdolescentMedicine and Health, vol. 24, no. 4, pp. 283-289, 2012.
7. K. Yuan, W. Qin, Y. Liu, and J. Tian,"Internet addiction: neuroimaging findings," Communicative and Integrative Biology, vol. 4, no. 6, pp. 637-639, 2011.
8. K. S. Young,"Internet addiction: the emergence of a new clinical disorder," Cyberpsychology and Behavior, vol. 1, no. 3, pp. 237-244, 1998.
9. K. W. Beard and E. M. Wolf,"Modification in the proposed diagnostic criteria for Internet addiction," Cyberpsychology and Behavior, vol. 4, no. 3, pp. 377-383, 2001.
10. K. S. Yong, Caught in the Net: How to Recognize the Signs of Internet Addiction and a Winning Strategy for Recovery, John Wiley & Sons, New York, NY, USA, 1998.
11. L. Widyanto and M. McMurran,"The psychometric properties of the internet addiction test," Cyberpsychology and Behavior, vol. 7, no. 4, pp. 443-450, 2004.
12. R. Tao, X. Huang, J. Wang, H. Zhang, Y. Zhang, and M. Li,"Proposed diagnostic criteria for internet addiction," Addiction, vol. 105, no. 3, pp. 556-564, 2010.
13. C.-H. Ko, J.-Y. Yen, S.-H. Chen, M.-J. Yang, H.-C. Lin, and C.-F. Yen,"Proposed diagnostic criteria and the screening and diagnosing tool of Internet addiction in college students," Comprehensive Psychiatry, vol. 50, no. 4, pp. 378-384, 2009.
14. N. A. Shapira, M. C. Lessig, T. D. Goldsmith et al.,"Problematic internet use: proposed classification and diagnostic criteria," Depression and Anxiety, vol. 17, no. 4, pp. 207-216, 2003.
15. C. H. Ko, J. Y. Yen, C. C. Chen, S. H. Chen, and C. F. Yen,"Proposed diagnostic criteria of internet addiction for adolescents," Journal of Nervous and Mental Disease, vol. 193, no. 11, pp. 728-733, 2005.
16. G.-J. Meerkerk, R. J. J. M. van Den Eijnden, A. A. Vermulst, and H. F. L. Garretsen,"The Compulsive Internet Use Scale (CIUS): some psychometric properties," Cyberpsychology and Behavior, vol. 12, no. 1, pp. 1-6, 2009.
17. M. L. James and S. S. Gambhir,"A molecular imaging primer: modalities, imaging agents, and applications," Physiological Reviews, vol. 92, no. 2, pp. 897-965, 2012.
18. R. Weissleder and U. Mahmood,"Molecular imaging," Radiology, vol. 219, no. 2, pp. 316-333, 2001.
19. A. M. Blamire,"The technology of MRI-the next 10 years?" British Journal of Radiology, vol. 81, no. 968, pp. 601-617, 2008.
20. N. K. Logothetis,"The neural basis of the blood-oxygen-level-dependent functional magnetic resonance imaging signal," Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 357, no. 1424, pp. 1003-1037, 2002.
21. N. K. Logothetis and B. A. Wandell,"Interpreting the BOLD signal," Annual Review of Physiology, vol. 66, pp. 735-769, 2004.
22. C. M. MacLeod and P. A. MacDonald,"Interdimensional interference in the Stroop effect: uncovering the cognitive and neural anatomy of attention," Trends in Cognitive Sciences, vol. 4, no. 10, pp. 383-391, 2000.
23. K. Yuan, P. Cheng, T. Dong et al.,"Cortical thickness abnormalities in late adolescence with online gaming addiction," PLoS ONE, vol. 8, no. 1, Article ID e53055, 2013.
24. S.-B. Hong, J.-W. Kim, E.-J. Choi et al.,"Reduced orbitofrontal cortical thickness in male adolescents with internet addiction," Behavioral and Brain Functions, vol. 9, no. 1, article 11, 2013.
25. B. J. Everitt, D. M. Hutcheson, K. D. Ersche, Y. Pelloux, J. W. Dalley, and T. W. Robbins,"The orbital prefrontal cortex and drug addiction in laboratory animals and humans," Annals of the New York Academy of Sciences, vol. 1121, pp. 576-597, 2007.
26. F. Lucantonio, T. A. Stalnaker, Y. Shaham, Y. Niv, and G. Schoenbaum,"The impact of orbitofrontal dysfunction on cocaine addiction," Nature Neuroscience, vol. 15, no. 3, pp. 358-366, 2012.
27. A. E. Cavanna and M. R. Trimble,"The precuneus: a review of its functional anatomy and behavioural correlates," Brain, vol. 129, no. 3, pp. 564-583, 2006.
28. S. Grant, E. D. London, D. B. Newlin et al.,"Activation of memory circuits during cue-elicited cocaine craving," Proceedings of the National Academy of Sciences of the United States of America, vol. 93, no. 21, pp. 12040-12045, 1996.
29. C. D. Kilts, J. B. Schweitzer, C. K. Quinn et al.,"Neural activity related to drug craving in cocaine addiction," Archives of General Psychiatry, vol. 58, no. 4, pp. 334-341, 2001.
30. J. Ashburner and K. J. Friston,"Voxel-based morphometry-the methods," NeuroImage, vol. 11, no. 6 I, pp. 805-821, 2000.
31. J. L. Whitwell,"Voxel-based morphometry: an automated technique for assessing structural changes in the brain," Journal of Neuroscience, vol. 29, no. 31, pp. 9661-9664, 2009.
32. Y. Zhou, F.-C. Lin, Y.-S. Du et al.,"Gray matter abnormalities in internet addiction: a voxel-based morphometry study," European Journal of Radiology, vol. 79, no. 1, pp. 92-95, 2011.
33. K. Yuan, W. Qin, G. Wang et al.,"Microstructure abnormalities in adolescents with internet addiction disorder," PLoS ONE, vol. 6, no. 6, Article ID e20708, 2011.
34. C.-B. Weng, R.-B. Qian, X.-M. Fu et al.,"Gray matter and white matter abnormalities in online game addiction," European Journal of Radiology, vol. 82, no. 8, pp. 1308-1312, 2013.
35. E. K. Miller and J. D. Cohen,"An integrative theory of prefrontal cortex function," Annual Review of Neuroscience, vol. 24, pp. 167-202, 2001.
36. R. Z. Goldstein and N. D. Volkow,"Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications," Nature Reviews Neuroscience, vol. 12, no. 11, pp. 652-669, 2011.
37. G. Schoenbaum, M. R. Roesch, and T. A. Stalnaker,"Orbitofrontal cortex, decision-making and drug addiction," Trends in Neurosciences, vol. 29, no. 2, pp. 116-124, 2006.
38. A. W. MacDonald III, J. D. Cohen, V. A. Stenger, and C. S. Carter,"Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control," Science, vol. 288, no. 5472, pp. 1835-1838, 2000.
39. D. C. Krawczyk,"Contributions of the prefrontal cortex to the neural basis of human decision making," Neuroscience and Biobehavioral Reviews, vol. 26, no. 6, pp. 631-664, 2002.
40. N. H. Naqvi and A. Bechara,"The hidden island of addiction: the insula," Trends in Neurosciences, vol. 32, no. 1, pp. 56-67, 2009.
41. N. H. Naqvi, D. Rudrauf, H. Damasio, and A. Bechara,"Damage to the insula disrupts addiction to cigarette smoking," Science, vol. 315, no. 5811, pp. 531-534, 2007.
42. M. Contreras, F. Ceric, and F. Torrealba,"Inactivation of the interoceptive insula disrupts drug craving and malaise induced by lithium," Science, vol. 318, no. 5850, pp. 655-658, 2007.
43. D. Le Bihan, J.-F. Mangin, C. Poupon et al.,"Diffusion tensor imaging: concepts and applications," Journal of Magnetic Resonance Imaging, vol. 13, no. 4, pp. 534-546, 2001.
44. D. S. Tuch, T. G. Reese, M. R. Wiegell, and V. J. Wedeen,"Diffusion MRI of complex neural architecture," Neuron, vol. 40, no. 5, pp. 885-895, 2003.
45. G. Dong, E. DeVito, J. Huang, and X. Du,"Diffusion tensor imaging reveals thalamus and posterior cingulate cortex abnormalities in internet gaming addicts," Journal of Psychiatric Research, vol. 46, no. 9, pp. 1212-1216, 2012.
46. F. Lin, Y. Zhou, Y. Du et al.,"Abnormal white matter integrity in adolescents with internet addiction disorder: a tract-based spatial statistics study," PLoS ONE, vol. 7, no. 1, Article ID e30253, 2012.
47. Q. Feng, X. Chen, J. Sun et al.,"Voxel-level comparison of arterial spin-labeled perfusion magnetic resonance imaging in adolescents with internet gaming addiction," Behavioral and Brain Functions, vol. 9, no. 1, article 33, 2013.
48. N. D. Volkow, G.-J. Wang, J. S. Fowler, D. Tomasi, F. Telang, and R. Baler,"Addiction: decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit," BioEssays, vol. 32, no. 9, pp. 748-755, 2010.
49. C. P. O'Brien, A. R. Childress, R. Ehrman, and S. J. Robbins,"Conditioning factors in drug abuse: can they explain compulsion?" Journal of Psychopharmacology, vol. 12, no. 1, pp. 15-22, 1998.
50. W.-N. Ding, J.-H. Sun, Y.-W. Sun et al.,"Altered default network resting-state functional connectivity in adolescents with internet gaming addiction," PLoS ONE, vol. 8, no. 3, Article ID e59902, 2013.
51. S.-B. Hong, A. Zalesky, L. Cocchi et al.,"Decreased functional brain connectivity in adolescents with internet addiction," PLoS ONE, vol. 8, no. 2, Article ID e57831, 2013.
52. H. W. Lee, J.-S. Choi, Y.-C. Shin, J.-Y. Lee, H. Y. Jung, and J. S. Kwon,"Impulsivity in internet addiction: a comparison with pathological gambling," Cyberpsychology, Behavior, and Social Networking, vol. 15, no. 7, pp. 373-377, 2012.
53. A. R. Aron, D. Shohamy, J. Clark, C. Myers, M. A. Gluck, and R. A. Poldrack,"Human midbrain sensitivity to cognitive feedback and uncertainty during classification learning," Journal of Neurophysiology, vol. 92, no. 2, pp. 1144-1152, 2004.
54. C.-H. Ko, T.-J. Hsieh, C.-Y. Chen et al.,"Altered brain activation during response inhibition and error processing in subjects with Internet gaming disorder: a functional magnetic imaging study," European Archives of Psychiatry and Clinical Neuroscience, 2014.
55. S. L. Fryer, S. F. Tapert, S. N. Mattson, M. P. Paulus, A. D. Spadoni, and E. P. Riley,"Prenatal alcohol exposure affects frontal-striatal BOLD response during inhibitory control," Alcoholism: Clinical and Experimental Research, vol. 31, no. 8, pp. 1415-1424, 2007.
56. G. Dong, E. E. DeVito, X. Du, and Z. Cui,"Impaired inhibitory control in "internet addiction disorder": a functional magnetic resonance imaging study," Psychiatry Research-Neuroimaging, vol. 203, no. 2-3, pp. 153-158, 2012.
57. M. M. Botvinick, J. D. Cohen, and C. S. Carter,"Conflict monitoring and anterior cingulate cortex: an update," Trends in Cognitive Sciences, vol. 8, no. 12, pp. 539-546, 2004.
58. C. S. Carter and V. Van Veen,"Anterior cingulate cortex and conflict detection: an update of theory and data," Cognitive, Affective and Behavioral Neuroscience, vol. 7, no. 4, pp. 367-379, 2007.
59. R. Leech and D. J. Sharp,"The role of the posterior cingulate cortex in cognition and disease," Brain, vol. 137, no. 1, pp. 12-32, 2014.
60. Y. Zang, T. Jiang, Y. Lu, Y. He, and L. Tian,"Regional homogeneity approach to fMRI data analysis," NeuroImage, vol. 22, no. 1, pp. 394-400, 2004.
61. G. Dong, J. Huang, and X. Du,"Alterations in regional homogeneity of resting-state brain activity in internet gaming addicts," Behavioral and Brain Functions, vol. 8, article 41, 2012.
62. C.-H. Ko, G.-C. Liu, S. Hsiao et al.,"Brain activities associated with gaming urge of online gaming addiction," Journal of Psychiatric Research, vol. 43, no. 7, pp. 739-747, 2009.
63. Y. Sun, H. Ying, R. M. Seetohul et al.,"Brain fMRI study of crave induced by cue pictures in online game addicts (male adolescents)," Behavioural Brain Research, vol. 233, no. 2, pp. 563-576, 2012.
64. C.-H. Ko, G.-C. Liu, J.-Y. Yen, C.-F. Yen, C.-S. Chen, and W.-C. Lin,"The brain activations for both cue-induced gaming urge and smoking craving among subjects comorbid with Internet gaming addiction and nicotine dependence," Journal of Psychiatric Research, vol. 47, no. 4, pp. 486-493, 2013.
65. D. H. Han, Y. S. Kim, Y. S. Lee, K. J. Min, and P. F. Renshaw,"Changes in cue-induced, prefrontal cortex activity with videogame play," Cyberpsychology, Behavior, and Social Networking, vol. 13, no. 6, pp. 655-661, 2010.
66. N. D. Volkow, G.-J. Wang, J. S. Fowler, and D. Tomasi,"Addiction circuitry in the human brain," Annual Review of Pharmacology and Toxicology, vol. 52, pp. 321-336, 2012.
67. C.-H. Ko, G.-C. Liu, J.-Y. Yen, C.-Y. Chen, C.-F. Yen, and C.-S. Chen,"Brain correlates of craving for online gaming under cue exposure in subjects with Internet gaming addiction and in remitted subjects," Addiction Biology, vol. 18, no. 3, pp. 559-569, 2013.
68. D. H. Han, J. W. Hwang, and P. F. Renshaw,"Bupropion sustained release treatment decreases craving for video games and cue-induced brain activity in patients with internet video game addiction," Experimental and Clinical Psychopharmacology, vol. 18, no. 4, pp. 297-304, 2010.
69. M. Tian, Q. Chen, Y. Zhang et al.,"PET imaging reveals brain functional changes in internet gaming disorder," European Journal of Nuclear Medicine and Molecular Imaging, vol. 41, no. 7, pp. 1388-1397, 2014.
70. T. Jones and E. A. Rabiner,"The development, past achievements, and future directions of brain PET," Journal of Cerebral Blood Flow and Metabolism, vol. 32, no. 7, pp. 1426-1454, 2012.
71. M. E. Phelps,"Positron emission tomography provides molecular imaging of biological processes," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 16, pp. 9226-9233, 2000.
72. M. Laruelle,"Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review," Journal of Cerebral Blood Flow and Metabolism, vol. 20, no. 3, pp. 423-451, 2000.
73. H. S. Park, S. H. Kim, S. A. Bang, E. J. Yoon, S. S. Cho, and S. E. Kim,"Altered regional cerebral glucose metabolism in internet game overusers: a 18F-fluorodeoxyglucose positron emission tomography study," CNS Spectrums, vol. 15, no. 3, pp. 159-166, 2010.
74. J. D. Berke and S. E. Hyman,"Addiction, dopamine, and the molecular mechanisms of memory," Neuron, vol. 25, no. 3, pp. 515-532, 2000.
75. N. D. Volkow, J. S. Fowler, G.-J. Wang, J. M. Swanson, and F. Telang,"Dopamine in drug abuse and addiction: results of imaging studies and treatment implications," Archives of Neurology, vol. 64, no. 11, pp. 1575-1579, 2007.
76. M. J. Koepp, R. N. Gunn, A. D. Lawrence et al.,"Evidence for striatal dopamine release during a video game," Nature, vol. 393, no. 6682, pp. 266-268, 1998.
77. S. H. Kim, S.-H. Baik, C. S. Park, S. J. Kim, S. W. Choi, and S. E. Kim,"Reduced striatal dopamine D2 receptors in people with Internet addiction," NeuroReport, vol. 22, no. 8, pp. 407-411, 2011.
78. D. H. Han, Y. S. Lee, K. C. Yang, E. Y. Kim, I. K. Lyoo, and P. F. Renshaw,"Dopamine genes and reward dependence in adolescents with excessive internet video game play," Journal of Addiction Medicine, vol. 1, no. 3, pp. 133-138, 2007.
79. R. A. Vaughan and J. D. Foster,"Mechanisms of dopamine transporter regulation in normal and disease states," Trends in Pharmacological Sciences, vol. 34, no. 9, pp. 489-496, 2013.
80. B. K. Gorentla and R. A. Vaughan,"Differential effects of dopamine and psychoactive drugs on dopamine transporter phosphorylation and regulation," Neuropharmacology, vol. 49, no. 6, pp. 759-768, 2005.
81. K. C. Schmitt and M. E. A. Reith,"Regulation of the dopamine transporter: aspects relevant to psychostimulant drugs of abuse," Annals of the New York Academy of Sciences, vol. 1187, pp. 316-340, 2010.
82. H. Hou, S. Jia, S. Hu et al.,"Reduced striatal dopamine transporters in people with internet addiction disorder," Journal of Biomedicine and Biotechnology, vol. 2012, Article ID 854524,5 pages, 2012.
83. A. Badiani, D. Belin, D. Epstein, D. Calu, and Y. Shaham,"Opiate versus psychostimulant addiction: the differences do matter," Nature Reviews Neuroscience, vol. 12, no. 11, pp. 685-700, 2011.
84. A. M. Przepiorka, A. Blachnio, B. Miziak, and S. J. Czuczwar,"Clinical approaches to treatment of Internet addiction," Pharmacological Reports, vol. 66, no. 2, pp. 187-191, 2014.
85. L. Dutra, G. Stathopoulou, S. L. Basden, T. M. Leyro, M. B. Powers, and M. W. Otto,"A meta-analytic review of psychosocial interventions for substance use disorders," The American Journal of Psychiatry, vol. 165, no. 2, pp. 179-187, 2008.
86. K. S. Young,"Cognitive behavior therapy with internet addicts: treatment outcomes and implications," Cyberpsychology and Behavior, vol. 10, no. 5, pp. 671-679, 2007.