Degradation of gamma secretase activating protein by the ubiquitin-proteasome pathway

Journal of Neurochemistry

Volumn 133, Issue 3, 2015, Pages 432-439

  Chu, Jin ^a   Li, Jian Guo ^a   Hoffman, Nicholas E ^b   Madesh, Muniswamy ^b   Praticò, Domenico ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEMPLE UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; amyloid ; APP; protein degradation; secretase activating protein

Indexed keywords

AMYLOID BETA PROTEIN; CALPASTATIN; GAMMA SECRETASE; GAMMA SECRETASE ACTIVATING PROTEIN; LYSOSOME INHIBITOR; PEPTIDES AND PROTEINS; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN; UNCLASSIFIED DRUG; GAMMA-SECRETASE ACTIVATING PROTEIN, HUMAN; PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME METABOLISM; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MICROSCOPY; NERVE CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; STEADY STATE; UBIQUITINATION; WESTERN BLOTTING; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CELL LINE, TUMOR; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84927137056     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13011     Document Type: Article

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