ADAM protease inhibitors reduce melanogenesis by regulating PMEL17 processing in human melanocytes

Journal of Dermatological Science

Volumn 78, Issue 2, 2015, Pages 133-142

  Kawaguchi, Masakazu ^a   Hozumi, Yutaka ^a   Suzuki, Tamio ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

ADAM protease; Melanocyte; Melanogenesis; Melanosome; PMEL17

Indexed keywords

ADAM PROTEASE INHIBITOR; ALPHA INTERMEDIN; BETA SECRETASE 2; GAMMA SECRETASE; MELANOCYTE PROTEIN PMEL 17; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PROTEINASE INHIBITOR; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG; ADAM PROTEIN; ASPARTIC PROTEINASE; BACE2 PROTEIN, HUMAN; DIPEPTIDE; INTERFERON; MELANIN; MITF PROTEIN, HUMAN; MONOPHENOL MONOOXYGENASE; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; PLACENTA PROTEIN; PMEL PROTEIN, HUMAN; SECRETASE; SMALL INTERFERING RNA; TROPHOBLAST PROTEIN 1;

ALAMARBLUE CELL PROLIFERATION ASSAY; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; MELANIN CONTENT ASSAY; MELANOCYTE; MELANOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; RNA INTERFERENCE; TYROSINASE ACTIVITY ASSAY; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; EXPERIMENTAL MELANOMA; GENETICS; MELANOSOME; METABOLISM; TUMOR CELL LINE; ULTRASTRUCTURE;

ADAM PROTEINS; ALPHA-MSH; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ACID ENDOPEPTIDASES; CELL LINE, TUMOR; DIPEPTIDES; GP100 MELANOMA ANTIGEN; HUMANS; INTERFERON TYPE I; MELANINS; MELANOCYTES; MELANOMA, EXPERIMENTAL; MELANOSOMES; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MICROSCOPY, ELECTRON; MONOPHENOL MONOOXYGENASE; PREGNANCY PROTEINS; PROTEASE INHIBITORS; RNA, SMALL INTERFERING;

EID: 84927094508     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2015.02.020     Document Type: Article

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