Enhanced Melanogenesis Induced by Tyrosinase Gene-Transfer Increases Boron-Uptake and Killing Effect of Boron Neutron Capture Therapy for Amelanotic Melanoma

Pigment Cell Research

Volumn 11, Issue 5, 1998, Pages 275-282

  Tsuboi, Tatsuya ^a   Kondoh, Hirofumi ^a   Hiratsuka, Junichi ^b   Mishima, Yutaka ^a  

^a Mishima Institute for Dermatological Research   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

10B BPA; Amelanotic melanoma; BNCT; Gene transfer; Melanin monomers

Indexed keywords

4 BORONOPHENYLALANINE; 4-BORONOPHENYLALANINE; BORON DERIVATIVE; DOPACHROME; DRUG DERIVATIVE; INDOLE DERIVATIVE; MELANIN; MONOPHENOL MONOOXYGENASE; PHENYLALANINE; QUINONE DERIVATIVE;

AMELANOTIC MELANOMA; ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; GENE EXPRESSION; GENE TRANSFER; GENETICS; KINETICS; METABOLISM; METHODOLOGY; MOUSE; NEUTRON CAPTURE THERAPY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; CELLS, CULTURED; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; INDOLEQUINONES; INDOLES; KINETICS; MELANINS; MELANOMA, AMELANOTIC; MICE; MONOPHENOL MONOOXYGENASE; PHENYLALANINE; QUINONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0032174790     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0749.1998.tb00736.x     Document Type: Article

References (38)

1. Ando, O., Y. Mishima, S. Hanada, Y. Suemoto, J. Atobe, and M. Kurimoto (1993) Analyses of mixed melanogenesis in tyrosinase cDNA-transfected human amelanotic melanoma cells. J. Invest. Dermatol. 101:864-870.
2. Barber, J.I., A.W. Townsend, D.P. Olds, and R.A. King (1984) Dopachrome oxidoreductase: A new enzyme in the pigment pathway. J. Invest. Dermatol. 83:145-149.
3. Bouchard, B., B.B. Fuller, S. Vijayasaradhi, and A.N. Houghton (1989) Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA. J. Exp. Med. 169:2029-2042.
4. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
5. Brossart, P., U. Keiholz, M. Willhauck, C. Seheibenbogen, T. Möhler, and W Hunstein (1993) Hematogenous spread of malignant melanoma cells in different stages of disease. J. Invest. Dermatol. 101:887-889.
6. Coderre, J.A., J.D. Glass, S. Packer, P. Micca, and D. Greenberg (1990) Experimental boron neutron capture therapy for melanoma: systemic delivery of boron to melanotic and amelanotic melanoma. Pigment Cell Res. 3:310-318.
7. Coderre, J.A., G.M. Morris, P.L. Micca, M.M. Nawrocky, C.D. Fisher, A.Bywaters, and J.W Hopewell (1996) The therapeutic ratio in BNCT: Assessment using the rat 9L gliosarcoma brain tumor and spinal cord models. In: Cancer neutron capture therapy. Y. Mishima, ed. Plenum Press, New York, pp. 757-762.
8. Cristiano, R.J., and J.A. Roth (1995) Molecular conjugates: A targeted gene delivery vector for molecular medicine. J. Mol. Med. 73:479-486.
9. Eberle, J., C. Garbe, N. Wang, and C.E. Orfanos (1995) Incomplete expression of the tyrosinase gene family (tyrosinase, TRP-1, and TRP-2) in human malignant melanoma cells in vitro. Pigment Cell Res. 8:307-313.
10. Elowitz, E.H., M. Chadha, J. Iwai, J.A. Coderre, D.D. Joel, D.N. Slatkin, and A.D. Chanana (1997) A phase I/II trial of BNCT for glioblastoma multiforme using intravenouse boronophenylalanine-fructose complex and epithermal neutrons: Early clinical results.In: Advances in neutron capture therapy. B. Larsson, J. Crawford, and R. Weinreich, eds. Elsevier Science, Amsterdam, pp. 56-59.
11. Fairchild, R.G., and L.J. Goodman (1966) Development and dosimetry of an "epithermal" neutron beam for possible use in neutron capture therapy. Phys. Med. Biol. 2:15-30.
12. Hatanaka, H., and Y. Nakagawa (1994) Clinical results of long-surviving brain tumor patients who underwent boron neutron capture therapy. Int. J. Radiat. Oncol. Biol. Phys. 28:1061-1066.
13. Hatta, S., M. Mishima, M. Ichihashi, and S. Ito (1988) Melanin monomers within coated vesicles and premelanosomes in melanin synthesizing cells. J. Invest. Dermatol. 91:181-184.
14. 10B-neutron capture therapy for early skin reaction in the hamster. Radiat. Res. 128:186-191.
15. Ito, S., K. Wakamatsu, and H. Ozeki (1993) Spectrophotometric assay of eumelanin in tissue samples. Anal. Biochem. 215:273-277.
16. Karasuyama, H., N. Tohyama, and T. Tada (1989) Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene. J. Exp. Med. 169:13-25.
17. Kondoh, H., A. Wilczek, S. Shibahara, and Y. Mishima (1994) The role of DOPAchrome tautomerase in eumelanogenesis: Analyses of TRP-2 cDNA-transfected human melanoma. Pigment Cell Res. 7:372 (abstract).
18. Kondoh, H., A. Wilczek, S. Narimizu, and Y. Mishima (1996) Mouse fibroblast expressing human tyrosinase with DHICA-oxidase activity produces predominantly pheomelanin deposit in lysosome. Zoological Sci. 13:825-831.
19. 10B-chlorpromazine compound. In: Mechanisms in pigmentation. V. J. McGovern and P. Russel, eds. Karger, Basel, Vol. 1, pp. 215-221.
20. 10B/melanogenesis interaction to in vitro/in vivo radiobiological analysis to preclinical studies. In: Proceedings of the 1st International Symposium on neutron capture therapy. R.G. Fairchild, and G.L. Brownel, eds. US Government Printing Office, New York, pp. 355-364.
21. Mishima, Y., and G. Imokawa (1985) Role of glycosylation in initial melanogenesis: Post-inhibition dynamics. In: Biological, molecular and clinical aspects of pigmentation. J. Bagnara, S.N. Klaus, E. Paul, and M. Schartl, eds. University of Tokyo Press, Tokyo, pp. 17-30.
22. 10B molecule-melanoma cell interaction from in vitro to first clinical trial. Pigment Cell Res. 2:226-234.
23. Mishima, Y. (1994) Molecular and biological control of melanogenesis through tyrosinase genes, and intrinsic and extrinsic regulatory factors. Pigment Cell Res. 7:376-387.
24. Mishima, Y. (1996) Selective thermal neutron capture therapy of cancer cells using their specific metabolic activities-melanoma as prototype.In: Cancer neutron capture therapy. Y. Mishima, ed. Plenum Press, New York, pp. 1-26.
25. Mishima, Y. (1997) Melanoma and non-melanoma neutron capture therapy using gene therapy: Overview. In: Advances in neutron capture therapy. B. Larsson, J. Crawford, and R. Weinreich, eds. Elsevier Science, Amsterdam, pp. 10-25.
26. Mishima, Y., H. Kondoh, T. Tsuboi, C. Honda, J. Hiratsuka, and K. Yoshino (1997) Novel melanogenic gene transfer-applied boron neutron capture therapy. Pigment Cell Res. 10:330 (abstract).
27. Pawelek, J.M., K.B. Low, and D. Bermudes (1997) Tumor-targeted salmonela as a novel anticancer vector. Cancer Res. 57:4537-4544.
28. Reinhold, U., H.C. Lüdtke-Handjery, S. Schnautz, H.W. Kreysel, and H. Abken (1997) The analysis of tyrosinase-specific mRNA in blood samples of melanoma patients by RT-PCR is not a useful test for metastatic tumor progression. J. Invest. Dermatol. 108:166-169.
29. 1-paraboronophenylalanine for malignant melanoma. J. Kobe Univ. School of Medicine. 53:35-41.
30. Smith, B., P. Selby, J. Southgate, K. Pittman, C. Bradley, and G.E. Blair (1991) Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet. 338:1227-1229.
31. Takeda, A., Y. Tomita, S. Okinaga, H. Tagami, and S. Shibahara (1989) Functional analysis of the cDNA encoding human tyrosinase pre-cursor. Biochem. Biophys. Res. Commun. 162:984-990.
32. Van Woert, M.H., and S.H. Palmer (1969) Inhibition of the growth of mouse melanoma by chlorpromazine. Cancer Res. 29:1952-1955.
33. Winder, A.J. (1991) Expression of a mouse tyrosinase cDNA in 3T3 Swiss mouse fibroblasts. Biochem. Biophys. Res. Commun. 178:739-745.
34. 1-p-Boronophenylalanine-HC1 by chemical determination of trace boron in biological materials. In: Kyoto Univ. Res. Reactor Inst. Technical Report 260:233-245.
35. Yoshino, K., M. Okamoto, H. Kakihana, and Y. Mori (1986) Chemical assay of boron and its distribution in melanoma-bearing subjects. In: Neutron capture therapy. H. Hatanaka, ed. Nishimura, Niigata, pp. 291-302.
36. Yoshino, K., Y. Mishima, M. Kimura, J. Hiratsuka, Y. Mori, S. Ito, and H. Kakihana (1997) Capture of p-boronophenylalanine in malignant melanoma cells by complex formation with melanin monomers, DOPA, DHI and DHICA. In: Advances in neutron capture therapy. B. Larsson, J. Crawford, and R. Weinreich, eds. Elsevier Science, Amsterdam, pp. 234-238.
37. Zhao, H., D.J. Eling, E.E. Medrano, and R.E. Boissy (1996) Retroviral infection with human tyrosinase-related protein (TRP-1) cDNA upregulates tyrosinase activity and melanin synthesis in a TRP-1-deficient melanoma cell line. J. Invest. Dermatol. 106:744-752.
38. Zhu, N., D. Liggitt, Y. Liu, and R. Debs (1993) Systemic gene expression after intravenous DNA delivery into adult mice. Science. 261:209-211.