Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier

European Journal of Immunology

Volumn 45, Issue 4, 2015, Pages 1043-1058

  Abadier, Michael ^a,b   Haghayegh Jahromi, Neda ^a,b   Cardoso Alves, Ludmila ^a   Boscacci, Rémy ^a   Vestweber, Dietmar ^c   Barnum, Scott ^d   Deutsch, Urban ^a   Engelhardt, Britta ^a   Lyck, Ruth ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^d University of Alabama at Birmingham   (United States)

Author keywords

Blood brain barrier; CD4+ effector memory T (TEM) cells; Diapedesis; EAE; ICAM 1

Indexed keywords

CD31 ANTIGEN; FORSKOLIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; INTERLEUKIN 1BETA; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; RECOMBINANT INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN; CELL ADHESION MOLECULE; ICAM-2 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL ISOLATION; CELL JUNCTION; CELL STIMULATION; CELL SURFACE; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; DIAPEDESIS; DISEASE SEVERITY; ELECTRIC RESISTANCE; ENDOTHELIUM; ENDOTHELIUM CELL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; T CELL DIAPEDESIS; T LYMPHOCYTE; UPREGULATION; ANIMAL; C57BL MOUSE; CELL ADHESION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MULTIPLE SCLEROSIS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

ANIMALS; ANTIGENS, CD; BLOOD-BRAIN BARRIER; CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CELL ADHESION MOLECULES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIAL CELLS; FEMALE; IMMUNOLOGIC MEMORY; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84926998042     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445125     Document Type: Article

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