Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS

European Journal of Immunology

Volumn 40, Issue 12, 2010, Pages 3489-3498

  Lélu, Karine ^a,b   Delpy, Laurent ^c   Robert, Virginie ^a   Foulon, Eliane ^a   Laffont, Sophie ^a   Pelletier, Lucette ^a,b   Engelhardt, Britta ^d   Guéry, Jean Charles ^a,b,e  

^a INSERM   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c CNRS   (France)

^d UNIVERSITY OF BERN   (Switzerland)

^e TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

EAE MS; Estrogen; Estrogen receptor; Inflammation; Th1 Th17 cells

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEMATOPOIETIC TISSUE; IMMUNE RESPONSE; INFLAMMATION; INFLAMMATORY CELL; LYMPHOCYTE HOMING; MOUSE; MULTIPLE SCLEROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TH17 CELL;

ADOPTIVE TRANSFER; ANIMALS; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CELLS, CULTURED; CYTOPROTECTION; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; HUMANS; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; MYELIN-ASSOCIATED GLYCOPROTEIN; OVARIECTOMY;

EID: 78649542915     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040678     Document Type: Article

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