Inhibition of Forkhead box protein M1 by thiostrepton increases chemosensitivity to doxorubicin in T-cell acute lymphoblastic leukemia

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 1457-1464

  Wang, Jian Yong ^a   Jia, Xiu Hong ^a   Xing, Hai Yan ^b   Li, You Jie ^a   Fan, Wen Wen ^c   Li, Na ^a   Xie, Shu Yang ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b BINZHOU PEOPLE S HOSPITAL   (China)

^c Qingdao Women and Children Health Care Centers   (China)

Author keywords

Doxorubicin; Forkhead box protein M1; T cell acute lymphoblastic leukemia; Thiostrepton

Indexed keywords

CASPASE 3; DOXORUBICIN; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTOR; MESSENGER RNA; RNA; THIOSTREPTON; UNCLASSIFIED DRUG; FOXM1 PROTEIN, HUMAN; GLUTATHIONE TRANSFERASE P1; GSTP1 PROTEIN, HUMAN;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CELL VIABILITY ASSAY; CHEMOSENSITIVITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ACCUMULATION; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC50; JURKAT CELL LINE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; T CELL ACUTE LYMPHOBLASTIC LEUKEMIA; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

APOPTOSIS; CELL PROLIFERATION; DOXORUBICIN; FORKHEAD TRANSCRIPTION FACTORS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE S-TRANSFERASE PI; HUMANS; JURKAT CELLS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RNA, MESSENGER; THIOSTREPTON;

EID: 84926686672     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3469     Document Type: Article

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