Ligustrazine derivate DLJ14 reduces multidrug resistance of K562/A02 cells by modulating GSTπ activity

Toxicology in Vitro

Volumn 25, Issue 4, 2011, Pages 937-943

  Song, Yu Ning ^a   Guo, Xiu Li ^a   Zheng, Bei Bei ^a   Liu, Xin Yong ^a   Dong, Xue ^a   Yu, Lu Gang ^b   Cheng, Yan Na ^a  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

C Jun NH2 terminal kinase (JNK); Glutathione S transferase (GST ); Ligustrazine derivate; Multidrug resistance (MDR)

Indexed keywords

2 (2,4 DIMETHOXYSTYRYL) 3,5,6 TRIMETHYLPYRAZINE; DLJ 14; DOXORUBICIN; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE P1; MESSENGER RNA; PYRAZINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VERAPAMIL;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL LEVEL; CELL STRAIN K 562; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EXPOSURE; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG SENSITIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MULTIDRUG RESISTANCE; MYELOID LEUKEMIA; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTIBIOTICS, ANTINEOPLASTIC; BLOTTING, WESTERN; CELL PROLIFERATION; DOWN-REGULATION; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE S-TRANSFERASE PI; HUMANS; K562 CELLS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; PYRAZINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VERAPAMIL;

EID: 79955479186     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.03.002     Document Type: Article

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