Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

Science Translational Medicine

Volumn 7, Issue 274, 2015, Pages

  Venneti, Sriram ^a   Dunphy, Mark P ^b   Zhang, Hanwen ^b   Pitter, Kenneth L ^b   Zanzonico, Patrick ^b   Campos, Carl ^b   Carlin, Sean D ^b   La Rocca, Gaspare ^b   Lyashchenko, Serge ^b   Ploessl, Karl ^c   Rohle, Daniel ^b   Omuro, Antonio M ^b   Cross, Justin R ^b   Brennan, Cameron W ^b   Weber, Wolfgang A ^b   Holland, Eric C ^d   Mellinghoff, Ingo K ^b   Kung, Hank F ^c   Lewis, Jason S ^b   Thompson, Craig B ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; FLUOROGLUTAMINE F 18; RADIOPHARMACEUTICAL AGENT; TEMOZOLOMIDE; UNCLASSIFIED DRUG; FLUORINE; GLUTAMINE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN METABOLISM; CHEMORADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG UPTAKE; EX VIVO STUDY; FEMALE; GLIOBLASTOMA; GLIOMA; HUMAN; IN VIVO STUDY; MALE; MIDDLE AGED; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OLIGODENDROGLIOMA; PET-CT SCANNER; PRIORITY JOURNAL; SINGLE DRUG DOSE; TUMOR VOLUME; BRAIN TUMOR; DISEASE COURSE; METABOLISM; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY;

BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; DISEASE PROGRESSION; FLUORINE RADIOISOTOPES; GLIOMA; GLUTAMINE; HUMANS; POSITRON-EMISSION TOMOGRAPHY;

EID: 84926661140     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa1009     Document Type: Article

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