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Volumn 407, Issue 1, 2015, Pages 331-341

On-line stop-flow two-dimensional liquid chromatography-mass spectrometry method for the separation and identification of triterpenoid saponins from ginseng extract

Author keywords

Chromatography; Ginseng; Stop flow; Triterpenoid saponins; Two dimensional liquid

Indexed keywords

CHROMATOGRAPHY; ELECTRODEPOSITION; ELECTROSPRAY IONIZATION; HYDROPHILICITY; IONIZATION OF LIQUIDS; LIQUID SUGAR; LIQUIDS; MASS SPECTROMETRY; METABOLITES; SPECTROMETRY;

EID: 84926653152     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-8219-4     Document Type: Article
Times cited : (43)

References (24)
  • 2
    • 33847104559 scopus 로고    scopus 로고
    • In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng
    • Wang W, Zhao YQ, Rayburn ER, Hill DL, Wang H, Zhang RW (2007) In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. Cancer Chemother Pharmacol 59(5):589-601
    • (2007) Cancer Chemother Pharmacol , vol.59 , Issue.5 , pp. 589-601
    • Wang, W.1    Zhao, Y.Q.2    Rayburn, E.R.3    Hill, D.L.4    Wang, H.5    Zhang, R.W.6
  • 3
    • 33745447386 scopus 로고    scopus 로고
    • Antimicrobial activity of saponins from Medicago sp.: Structure-activity relationship
    • Avato P, Bucci R, Tava A, Vitali C, Rosato A, Bialy Z, Jurzysta M (2006) Antimicrobial activity of saponins from Medicago sp.: structure-activity relationship. Phytother Res 20(6):454-457
    • (2006) Phytother Res , vol.20 , Issue.6 , pp. 454-457
    • Avato, P.1    Bucci, R.2    Tava, A.3    Vitali, C.4    Rosato, A.5    Bialy, Z.6    Jurzysta, M.7
  • 4
    • 69249148258 scopus 로고    scopus 로고
    • Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis
    • Zhu D,Wu L, Li CR,WangXW,Ma YJ, Zhong ZY, Zhao HB, Cui J, Xun SF, Huang XL, Zhou Z, Wang SQ (2009) Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis. J Cell Biochem 108(1):117-124
    • (2009) J Cell Biochem , vol.108 , Issue.1 , pp. 117-124
    • Zhu Dwu, L.1    Li Crwangxwma, Y.J.2    Zhong, Z.Y.3    Zhao, H.B.4    Cui, J.5    Xun, S.F.6    Huang, X.L.7    Zhou, Z.8    Wang, S.Q.9
  • 5
    • 0033979495 scopus 로고    scopus 로고
    • Highperformance thin-layer chromatographic determination of six major ginsenosides in Panax ginseng
    • Vanhaelen-Fastré RJ, Faes ML, Vanhaelen MH (2000) Highperformance thin-layer chromatographic determination of six major ginsenosides in Panax ginseng. J Chromatogr A 868(2):269-276
    • (2000) J Chromatogr A , vol.868 , Issue.2 , pp. 269-276
    • Vanhaelen-Fastré, R.J.1    Faes, M.L.2    Vanhaelen, M.H.3
  • 6
    • 77953658743 scopus 로고    scopus 로고
    • Rapid determination of ginsenoside Rg1, Re and Rb1 in ginseng samples by capillary electrophoresis
    • Tian Y, Lu Y, Xie J, Cheng Y, Qi R, Wu Y, Zhang S (2009) Rapid determination of ginsenoside Rg1, Re and Rb1 in ginseng samples by capillary electrophoresis. Anal Methods 1(3):203-207
    • (2009) Anal Methods , vol.1 , Issue.3 , pp. 203-207
    • Tian, Y.1    Lu, Y.2    Xie, J.3    Cheng, Y.4    Qi, R.5    Wu, Y.6    Zhang, S.7
  • 7
    • 0031581905 scopus 로고    scopus 로고
    • Gas chromatographic-mass spectrometric determination of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol for study on human urinary excretion of ginsenosides after ingestion of ginseng preparations
    • Cui J-F, Björkhem I, Eneroth P (1997) Gas chromatographic-mass spectrometric determination of 20(S)-protopanaxadiol and 20(S)-protopanaxatriol for study on human urinary excretion of ginsenosides after ingestion of ginseng preparations. J Chromatogr B 689(2):349-355
    • (1997) J Chromatogr B , vol.689 , Issue.2 , pp. 349-355
    • Cui, J.-F.1    Björkhem, I.2    Eneroth, P.3
  • 8
    • 84891834826 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography for selective separation of isomeric saponins
    • Guo X, Zhang X, Guo Z, Liu Y, Shen A, Jin G, Liang X (2014) Hydrophilic interaction chromatography for selective separation of isomeric saponins. J Chromatogr A 1325:121-128
    • (2014) J Chromatogr A , vol.1325 , pp. 121-128
    • Guo, X.1    Zhang, X.2    Guo, Z.3    Liu, Y.4    Shen, A.5    Jin, G.6    Liang, X.7
  • 9
    • 0029015583 scopus 로고
    • Sample dimensionality: A predictor of order-disorder in component peak distribution in multidimensional separation
    • Giddings JC (1995) Sample dimensionality: a predictor of order-disorder in component peak distribution in multidimensional separation. J Chromatogr A 703:3-15
    • (1995) J Chromatogr A , vol.703 , pp. 3-15
    • Giddings, J.C.1
  • 10
    • 45249120387 scopus 로고    scopus 로고
    • Metabonomics study on the effects of the ginsenoside Rg3 in a beta-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach
    • Wang Y,Wang J, Yao M, Zhao X, Fritsche J, Schmitt-Kopplin P, Cai Z,Wan D, Lu X, Yang S, Gu J, Haring HU, Schleicher ED, Lehmann R, Xu G (2008) Metabonomics study on the effects of the ginsenoside Rg3 in a beta-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach. Anal Chem 80(12):4680-4688
    • (2008) Anal Chem , vol.80 , Issue.12 , pp. 4680-4688
    • Wang Ywang, J.1    Yao, M.2    Zhao, X.3    Fritsche, J.4    Schmitt-Kopplin, P.5    Cai Zwan, D.6    Lu, X.7    Yang, S.8    Gu, J.9    Haring, H.U.10    Schleicher, E.D.11    Lehmann, R.12    Xu, G.13
  • 12
    • 84865354880 scopus 로고    scopus 로고
    • Comprehensive hydrophilic interaction and ion-pair reversed-phase liquid chromatography for analysis of di- to deca-oligonucleotides
    • Li Q, Lynen F,Wang J, Li H, Xu G, Sandra P (2012) Comprehensive hydrophilic interaction and ion-pair reversed-phase liquid chromatography for analysis of di- to deca-oligonucleotides. J Chromatogr A 1255:237-243
    • (2012) J Chromatogr A , vol.1255 , pp. 237-243
    • Li, Q.1    Lynen Fwang, J.2    Li, H.3    Xu, G.4    Sandra, P.5
  • 13
    • 84884995368 scopus 로고    scopus 로고
    • Toward unraveling grape tannin composition: Application of online hydrophilic interaction chromatography × reversed-phase liquid chromatography-time-of-flight mass spectrometry for grape seed analysis
    • Kalili KM, Vestner J, Stander MA, de Villiers A (2013) Toward unraveling grape tannin composition: application of online hydrophilic interaction chromatography × reversed-phase liquid chromatography-time-of-flight mass spectrometry for grape seed analysis. Anal Chem 85(19):9107-9115
    • (2013) Anal Chem , vol.85 , Issue.19 , pp. 9107-9115
    • Kalili, K.M.1    Vestner, J.2    Stander, M.A.3    De Villiers, A.4
  • 14
    • 49549097348 scopus 로고    scopus 로고
    • Novel, fully automatic hydrophilic interaction/reversed-phase column-switching high-performance liquid chromatographic system for the complementary analysis of polar and apolar compounds in complex samples
    • Wang Y, Lehmann R, Lu X, Zhao X, Xu G (2008) Novel, fully automatic hydrophilic interaction/reversed-phase column-switching high-performance liquid chromatographic system for the complementary analysis of polar and apolar compounds in complex samples. J Chromatogr A 1204(1):28-34
    • (2008) J Chromatogr A , vol.1204 , Issue.1 , pp. 28-34
    • Wang, Y.1    Lehmann, R.2    Lu, X.3    Zhao, X.4    Xu, G.5
  • 15
    • 74349085109 scopus 로고    scopus 로고
    • Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: Application to Quillaja saponins
    • Bankefors J, Nord LI, Kenne L (2010)Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: application to Quillaja saponins. J Chromatogr B 878(3-4):471-476
    • (2010) J Chromatogr B , vol.878 , Issue.3-4 , pp. 471-476
    • Bankefors, J.1    Nord, L.I.2    Kenne, L.3
  • 16
    • 84859343126 scopus 로고    scopus 로고
    • Comprehensive HILIC × RPLC with mass spectrometry detection for the analysis of saponins in Panax notoginseng
    • Xing Q, Liang T, Shen G, Wang X, Jin Y, Liang X (2012) Comprehensive HILIC × RPLC with mass spectrometry detection for the analysis of saponins in Panax notoginseng. Analyst 137(9): 2239-2249
    • (2012) Analyst , vol.137 , Issue.9 , pp. 2239-2249
    • Xing, Q.1    Liang, T.2    Shen, G.3    Wang, X.4    Jin, Y.5    Liang, X.6
  • 17
    • 77953535023 scopus 로고    scopus 로고
    • Development and optimization of a method for the separation of platycosides in Platycodi radix by comprehensive two-dimensional liquid chromatography with mass spectrometric detection
    • Jeong EK, Cha HJ, Ha YW, Kim YS, Ha IJ, Na YC (2010) Development and optimization of a method for the separation of platycosides in Platycodi radix by comprehensive two-dimensional liquid chromatography with mass spectrometric detection. J Chromatogr A 1217(26):4375-4382
    • (2010) J Chromatogr A , vol.1217 , Issue.26 , pp. 4375-4382
    • Jeong, E.K.1    Cha, H.J.2    Ha, Y.W.3    Kim, Y.S.4    Ha, I.J.5    Na, Y.C.6
  • 18
    • 38649091974 scopus 로고    scopus 로고
    • Development of a comprehensive twodimensional hydrophilic interaction chromatography/quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria
    • Wang Y, Lu X, Xu G (2008) Development of a comprehensive twodimensional hydrophilic interaction chromatography/quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria. J Chromatogr A 1181(1-2):51-59
    • (2008) J Chromatogr A , vol.1181 , Issue.1-2 , pp. 51-59
    • Wang, Y.1    Lu, X.2    Xu, G.3
  • 19
    • 84888039352 scopus 로고    scopus 로고
    • A novel stop-flow two-dimensional liquid chromatography-mass spectrometry method for lipid analysis
    • Wang S, Li J, Shi X, Qiao L, Lu X, Xu G (2013) A novel stop-flow two-dimensional liquid chromatography-mass spectrometry method for lipid analysis. J Chromatogr A 1321:65-72
    • (2013) J Chromatogr A , vol.1321 , pp. 65-72
    • Wang, S.1    Li, J.2    Shi, X.3    Qiao, L.4    Lu, X.5    Xu, G.6
  • 20
    • 84878907058 scopus 로고    scopus 로고
    • Effect of mobile phase additives on qualitative and quantitative analysis of ginsenosides by liquid chromatography hybrid quadrupole-time of flight mass spectrometry
    • Liang Y, Guan T, Zhou Y, Liu Y, Xing L, Zheng X, Dai C, Du P, Rao T, Zhou L, Yu X, Hao K, Xie L, Wang G (2013) Effect of mobile phase additives on qualitative and quantitative analysis of ginsenosides by liquid chromatography hybrid quadrupole-time of flight mass spectrometry. J Chromatogr A 1297:29-36
    • (2013) J Chromatogr A , vol.1297 , pp. 29-36
    • Liang, Y.1    Guan, T.2    Zhou, Y.3    Liu, Y.4    Xing, L.5    Zheng, X.6    Dai, C.7    Du, P.8    Rao, T.9    Zhou, L.10    Yu, X.11    Hao, K.12    Xie, L.13    Wang, G.14
  • 21
    • 26444539668 scopus 로고    scopus 로고
    • Orthogonality of separation in two-dimensional liquid chromatography
    • Gilar M, Olivova P, Daly AE, Gebler JC (2005) Orthogonality of separation in two-dimensional liquid chromatography. Anal Chem 77(19):6426-6434
    • (2005) Anal Chem , vol.77 , Issue.19 , pp. 6426-6434
    • Gilar, M.1    Olivova, P.2    Daly, A.E.3    Gebler, J.C.4
  • 22
    • 53049094346 scopus 로고    scopus 로고
    • Novel twodimensional reversed-phase liquid chromatography/hydrophilic interaction chromatography, an excellent orthogonal system for practical analysis
    • Liu Y, Xue X, Guo Z, Xu Q, Zhang F, Liang X (2008) Novel twodimensional reversed-phase liquid chromatography/hydrophilic interaction chromatography, an excellent orthogonal system for practical analysis. J Chromatogr A 1208(1-2):133-140
    • (2008) J Chromatogr A , vol.1208 , Issue.1-2 , pp. 133-140
    • Liu, Y.1    Xue, X.2    Guo, Z.3    Xu, Q.4    Zhang, F.5    Liang, X.6
  • 23
    • 84989028068 scopus 로고
    • Liquid secondary ionization, tandem and matrix-assisted laser desorption/ionization time-of-flight mass spectrometric characterization of glycosphingolipid derivatives
    • Perreault H, Costello CE (1994) Liquid secondary ionization, tandem and matrix-assisted laser desorption/ionization time-of-flight mass spectrometric characterization of glycosphingolipid derivatives. Org Mass Spectrom 29(12):720-735
    • (1994) Org Mass Spectrom , vol.29 , Issue.12 , pp. 720-735
    • Perreault, H.1    Costello, C.E.2
  • 24
    • 0037254722 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry of malonyl-ginsenosides in the authentication of ginseng
    • Kite GC, Howes MJ, Leon CJ, Simmonds MS (2003) Liquid chromatography/mass spectrometry of malonyl-ginsenosides in the authentication of ginseng. Rapid Commun Mass Spectrom 17(3): 238-244
    • (2003) Rapid Commun Mass Spectrom , vol.17 , Issue.3 , pp. 238-244
    • Kite, G.C.1    Howes, M.J.2    Leon, C.J.3    Simmonds, M.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.