Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: Application to Quillaja saponins

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 3-4, 2010, Pages 471-476

  Bankefors, Johan ^a   Nord, Lars I ^a,b   Kenne, Lennart ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b Q Med AB   (Sweden)

Author keywords

Chromatographic profiling; Metabolic analysis; Multiple stage mass spectrometry; Quillaja saponins; Two dimensional chromatography

Indexed keywords

2D-HPLC; BARK EXTRACTS; CHROMATOGRAPHIC CONDITIONS; CHROMATOGRAPHIC PROFILING; COMPLEX MIXTURE; ELECTROSPRAYS; FRAGMENT IONS; GRAPHICAL REPRESENTATIONS; ION TRAPS; IONISATION; MASS SPECTROMETRIC DETECTION; METABOLIC ANALYSIS; MINOR COMPONENTS; NATURAL PRODUCTS; NUMBER OF COMPONENTS; PROOF OF CONCEPT; QUILLAJA SAPONARIA; RETENTION TIME; STRUCTURAL INFORMATION; TWO-DIMENSIONAL CHROMATOGRAPHY; TWO-STAGE SEPARATION;

CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; GRAPHIC METHODS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; MIXTURES; SEPARATION; TWO DIMENSIONAL;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

NATURAL PRODUCT; PLANT EXTRACT; QUILLAJA SAPONARIA EXTRACT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BARK; DRUG DETERMINATION; DRUG MIXTURE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

BIOLOGICAL PRODUCTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPLEX MIXTURES; METABOLOME; QUILLAJA; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

QUILLAJA; QUILLAJA SAPONARIA;

EID: 74349085109     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.034     Document Type: Article

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