PGSE, OGSE, and sensitivity to axon diameter in diffusion MRI: Insight from a simulation study

Magnetic Resonance in Medicine

Volumn 75, Issue 2, 2016, Pages 688-700

  Drobnjak, Ivana ^a   Zhang, Hui ^a   Ianuş, Andrada ^a   Kaden, Enrico ^a   Alexander, Daniel C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

axon diameter; diffusion gradients; diffusion imaging; oscillating gradient spin echo; pulsed gradient spin echo

Indexed keywords

DIFFUSION; MAGNETIC RESONANCE IMAGING; SCANNING; SPIN POLARIZATION; SPINNING (FIBERS);

AXON DIAMETERS; DIFFUSION GRADIENTS; DIFFUSION IMAGING; OSCILLATING-GRADIENT SPIN ECHOS; PULSED GRADIENT SPIN ECHOS;

SIGNAL TO NOISE RATIO;

ARTICLE; COMPARTMENT MODEL; DIFFUSION WEIGHTED IMAGING; NERVE FIBER; NUCLEAR MAGNETIC RESONANCE SCANNER; OSCILLATING GRADIENT SPIN ECHO; PULSED GRADIENT SPIN ECHO; RADIOFREQUENCY; SIGNAL NOISE RATIO; SIMULATION; WAVEFORM; WHITE MATTER; ANATOMY AND HISTOLOGY; AXON; COMPUTER SIMULATION; HUMAN; IMAGE PROCESSING; IMAGING PHANTOM; PROCEDURES; SENSITIVITY AND SPECIFICITY; ULTRASTRUCTURE;

AXONS; COMPUTER SIMULATION; DIFFUSION MAGNETIC RESONANCE IMAGING; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PHANTOMS, IMAGING; SENSITIVITY AND SPECIFICITY; WHITE MATTER;

EID: 84926643566     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25631     Document Type: Article

References (52)

1. Ritchie JM,. On the relation between fibre diameter and conduction velocity in myelinated nerve fibres. Proc R Soc Lond B Biol Sci 1982; 217: 29-35.
2. Hursh JB,. Conduction velocity and diameter of nerve fibers. Am J Physiol 1939; 127: 140-153.
3. Piven J, Bailey J, Ranson BJ, Arndt S,. An MRI study of the corpus callosum in autism. Am J Psychiatry 1997; 154: 1051-1056.
4. Hughes JR,. Autism: the first firm finding = underconnectivity? Epilepsy Behav 2007; 11: 20-24.
5. Heads T, Pollock M, Robertson A, Sutherland WHF, Allpress S,. Sensory nerve pathology in amyotrophic lateral sclerosis. Acta Neuropatholo 1991; 82: 316-320.
6. Cluskey S, Ramsden DB,. Mechanisms of neurodegeneration in amyotrophic lateral sclerosis. Mol Pathol 2001; 54: 386.
7. Randall PL,. Schizophrenia, abnormal connection, and brain evolution. Med Hypotheses 1983; 10: 247-280.
8. Rice D, Barone S,. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 2000; 108 Suppl 3: 511-533.
9. Assaf Y, Blumenfeld-Katzir T, Yovel Y, Basser PJ,. AxCaliber: a method for measuring axon diameter distribution from diffusion MRI. Magn Reson Med 2008; 59: 1347-1354.
10. McNab JA, Edlow BL, Witzel T, et al., The human connectome project and beyond: initial applications of 300 mT/m gradients. Neuroimage 2013; 80: 234-245.
11. Alexander DC, Hubbard PL, Hall MG, Moore EA, Ptito M, Parker GJM, Dyrby TB,. Orientationally invariant indices of axon diameter and density from diffusion MRI. Neuroimage 2010; 52: 1374-1389.
12. Zhang H, Hubbard PL, Parker GJM, Alexander DC,. Axon diameter mapping in the presence of orientation dispersion with diffusion MRI. Neuroimage 2011; 56: 1301-1315.
13. Dyrby TB, Sgaard LV, Hall MG, Ptito M, Alexander DC,. Contrast and stability of the axon diameter index from microstructure imaging with diffusion MRI. Magn Reson Med 2013; 70: 711-721.
14. Avram AV, Özarslan E, Sarlls JE, Basser PJ,. In vivo detection of microscopic anisotropy using quadruple pulsed-field gradient (qPFG) diffusion MRI on a clinical scanner. Neuroimage 2013; 64: 229-239.
15. Komlosh ME, Özarslan E, Lizak MJ, Horkayne-Szakaly I, Freidlin RZ, Horkay F, Basser PJ,. Mapping average axon diameters in porcine spinal cord white matter and rat corpus callosum using d-PFG MRI. Neuroimage 2013; 78: 210-216.
16. Shemesh N, Özarslan E, Komlosh ME, Basser PJ, Cohen Y,. From single-pulsed field gradient to double-pulsed field gradient MR: gleaning new microstructural information and developing new forms of contrast in MRI. NMR Biomed 2010; 23: 757-780.
17. Ong HH, Wehrli FW,. Quantifying axon diameter and intra-cellular volume fraction in excised mouse spinal cord with q-space imaging. Neuroimage 2010; 51: 1360-1366.
18. Jespersen SN,. Equivalence of double and single wave vector diffusion contrast at low diffusion weighting. NMR Biomed 2012; 25: 813-818.
19. Gore JC, Xu J, Colvin DC, Yankeelov TE, Parsons EC, Does MD,. Characterization of tissue structure at varying length scales using temporal diffusion spectroscopy. NMR Biomed 2010; 23: 745-756.
20. Li H, Gore JC, Xu J,. Fast and robust measurement of microstructural dimensions using temporal diffusion spectroscopy. J Magn Reson 2014; 242: 4-9.
21. Drobnjak I, Siow B, Alexander DC,. Optimizing gradient waveforms for microstructure sensitivity in diffusion-weighted MR. J Magn Reson 2010; 206: 41-51.
22. Siow B, Drobnjak I, Chatterjee A, Lythgoe MF, Alexander DC,. Estimation of pore size in a microstructure phantom using the optimised gradient waveform diffusion weighted NMR sequence. J Magn Reson 2012; 214: 51-60.
23. Siow B, Drobnjak I, Ianus A, Christie IN, Lythgoe MF, Alexander DC,. Axon radius estimation with oscillating gradient spin echo (OGSE) diffusion MRI. Diffusion Fundam 2013; 18: 1-6.
24. Shemesh N, Álvarez GA, Frydman L,. Measuring small compartment dimensions by probing diffusion dynamics via non-uniform Oscillating-Gradient Spin-Echo (NOGSE) NMR. J Magn Reson 2013; 237: 49-62.
25. Callaghan PT,. Translational dynamics and magnetic resonance: principles of pulsed gradient spin echo NMR. Oxford University Press, Oxford; 2011.
26. Kakkar LS, Atkinson D, Chan RW, Drobnjak I,. Imaging microstructure: Application of oscillating gradient diffusion sequences on a 3T clinical MRI scanner. In: Proc Int Soc Magn Reson Med, Vol. 22, 2014, Abstract 4225 Milan.
27. Drobnjak I, Alexander DC,. Optimising time-varying gradient orientation for microstructure sensitivity in diffusion-weighted MR. J Magn Reson 2011; 212: 344-354.
28. Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC,. NODDI: Practical in vivo neurite orientation dispersion and density imaging of the human brain. NeuroImage 2012; 61: 1000-1016.
29. Mikula S, Binding J, Denk W,. Staining and embedding the whole mouse brain for electron microscopy. Nat Methods 2012; 9: 1198-1201.
30. Axer H, Axer M, Krings T, Keyserlingk DG,. Quantitative estimation of 3-D fiber course in gross histological sections of the human brain using polarized light. J Neurosci Methods 2001; 105: 121-131.
31. Assaf Y, Basser PJ,. Composite hindered and restricted model of diffusion (CHARMED) MR imaging of the human brain. Neuroimage 2005; 27: 48-58.
32. Assaf Y, Freidlin R, Rohde G, Basser P,. New modeling and experimental framework to characterize hindered and restricted water diffusion in brain white matter. Magn Reson Med 2004; 52: 965-978.
33. Alexander DC,. A general framework for experiment design in diffusion MRI and its application in measuring direct tissue-microstructure features. Magn Reson Med 2008; 60: 439-448.
34. Murday JS, Cotts RM,. Selfdiffusion coefficient of liquid lithium. J Chem Phys 2003; 48: 4938-4945.
35. Ianus A, Siow B, Drobnjak I, Zhang H, Alexander DC,. Gaussian phase distribution approximations for oscillating gradient spin echo diffusion MRI. J Magn Reson 2013; 227: 25-34.
36. Basser PJ, Mattiello J, LeBihan D,. MR diffusion tensor spectroscopy and imaging. Biophys J 1994; 66: 259-267.
37. Szafer A, Zhong J, Gore JC,. Theoretical model for water diffusion in tissues. Magn Reson Med 1995; 33: 697-712.
38. Drobnjak I, Cruz G, Alexander DC,. Optimising oscillating waveform-shape for pore size sensitivity in diffusion-weighted MR. Microporous Mesoporous Mater 2013; 178: 11-14.
39. Baron CA, Beaulieu C,. Oscillating Gradient Spin-Echo (OGSE) diffusion tensor imaging of the human brain. Magn Reson Med 2014; 72: 726-736.
40. Aggarwal M, Jones MV, Calabresi PA, Mori S, Zhang J,. Probing mouse brain microstructure using oscillating gradient diffusion MRI. Magn Reson Med 2012; 67: 98-109.
41. Drobnjak I, Zhang H, Hall MG, Alexander DC,. The matrix formalism for generalised gradients with time-varying orientation in diffusion NMR. J Magn Reson 2011; 210: 151-157.
42. Price WS,. Pulsed-field gradient nuclear magnetic resonance as a tool for studying translational diffusion: part 1. Basic theory. Concepts Magn Reson 1997; 9: 299-336.
43. Bar-Shir A, Avram L, Ozarslan E, Basser P, Cohen Y,. The effect of the diffusion time and pulse gradient duration ratio on the diffraction pattern and the structural information estimated from q-space diffusion MR: experiments and simulations. J Magn Reson 2008; 194: 230-236.
44. Aboitiz F, Scheibel AB, Fisher RS, Zaidel E,. Fiber composition of the human corpus callosum. Brain Res 1992; 598: 143-153.
45. Shemesh N, Adiri T, Cohen Y,. Probing microscopic architecture of opaque heterogeneous systems using double-pulsed-field-gradient NMR. J Am Chem Soc 2011; 133: 6028-6035.
46. Novikov DS, Fieremans E, Jensen J, Helpern J,. Random walks with barriers. Nat Phys 2011; 7: 508-514.
47. Lam WW, Jbabdi S, Miller KL,. A model for extra-axonal diffusion spectra with frequency-dependent restriction. Magn Reson Med 2015; 73: 2306-2320.
48. 2, magnetization transfer, and quantitative histology in white matter tracts of rat spinal cord. Magn Reson Med 2010; 63: 902-909.
49. Callaghan PT, Coy A, MacGowan D, Packer K, Zelaya F,. Diffraction-like effects in NMR diffusion studies of fluids in porous solids. Nature 1991; 351: 467-469.
50. Topgaard D, Söderman O,. Experimental determination of pore shape and size using q-space NMR microscopy in the long diffusion-time limit. Magn Reson Imaging 2003; 21: 69-76.
51. Shemesh N, Westin CF, Cohen Y,. Magnetic resonance imaging by synergistic diffusion-diffraction patterns. Physical Review Letters 2012; 108: 058103.
52. Shemesh N, Özarslan E, Basser PJ, Cohen Y,. Detecting diffusion-diffraction patterns in size distribution phantoms using double-pulsed field gradient NMR: theory and experiments. J Chem Phys 2010; 132: 034703.