Adenosine derived from ecto-nucleotidases in calcific aortic valve disease promotes mineralization through A2a adenosine receptor

Cardiovascular Research

Volumn 106, Issue 1, 2015, Pages 109-120

  Mahmut, Ablajan ^a   Boulanger, Marie Chloe ^a   Bouchareb, Rihab ^a   Hadji, Fayez ^a   Mathieu, Patrick ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

5 nucleotidase; A2a receptor; Adenosine; Aortic stenosis; Biomineralization; Calcific aortic valve disease; Calcific aortic valve stenosis; CD73; CREB; Ectopic mineralization; ENPP1; NPP1; NT5E; PKA

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR STIMULATING AGENT; ADENOSINE TRIPHOSPHATE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ECTONUCLEOTIDASE; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; G PROTEIN COUPLED RECEPTOR; NUCLEOTIDASE; PROTEIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; ECTOATPASE; INORGANIC PYROPHOSPHATASE; PHOSPHODIESTERASE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA VALVE DISEASE; AORTA VALVE STENOSIS; ARTICLE; BIOMINERALIZATION; BLOOD VESSEL CALCIFICATION; CALCIFIC AORTIC VALVE DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE SILENCING; GENETIC TRANSFECTION; HEART VALVE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEYDIG CELL; MALE; MIDDLE AGED; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; VERY ELDERLY; ANIMAL; AORTA VALVE; CALCINOSIS; COMPARATIVE STUDY; CONGENITAL HEART MALFORMATION; DEFICIENCY; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VALVULAR HEART DISEASE;

5'-NUCLEOTIDASE; ADENOSINE; ADENOSINE TRIPHOSPHATASES; AGED; ANIMALS; AORTIC VALVE; AORTIC VALVE STENOSIS; CALCINOSIS; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DISEASE MODELS, ANIMAL; FEMALE; HEART DEFECTS, CONGENITAL; HEART VALVE DISEASES; HUMANS; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RECEPTOR, ADENOSINE A2A; SIGNAL TRANSDUCTION;

EID: 84926639299     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvv027     Document Type: Article

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