Inhibition of ectonucleotidase with ARL67156 prevents the development of calcific aortic valve disease in warfarin-treated rats

European Journal of Pharmacology

Volumn 689, Issue 1-3, 2012, Pages 139-146

  Côté, Nancy ^a   El Husseini, Diala ^a   Pépin, Andrée ^a   Bouvet, Céline ^c   Gilbert, Liz Ann ^c   Audet, Audrey ^a   Fournier, Dominique ^a   Pibarot, Philippe ^b   Moreau, Pierre ^c   Mathieu, Patrick ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Akt; ARL67156; Calcific aortic valve disease; Ectonucleotidase; ENPP1; Mineralization; Warfarin

Indexed keywords

BETA,GAMMA DIBROMOMETHYLENE 6 N,N DIETHYLADENOSINE TRIPHOSPHATE; ECTONUCLEOTIDASE; ECTONUCLEOTIDE PYROPHOSPHATASE; NUCLEOTIDASE; NUCLEOTIDE PYROPHOSPHATASE; PHOSPHODIESTERASE I; PROTEIN KINASE B; UNCLASSIFIED DRUG; WARFARIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA STENOSIS; AORTA VALVE DISEASE; AORTIC VALVE CALCIFICATION; APOPTOSIS; ARTICLE; BLOOD VESSEL CALCIFICATION; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; DRUG TARGETING; ENZYME INHIBITION; EX VIVO STUDY; EXPERIMENTAL RAT; GENE EXPRESSION PROFILING; MALE; MINERALIZATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; STAINING; SURVIVAL RATE; VON KOSSA STAINING;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; AORTIC VALVE STENOSIS; CALCINOSIS; MALE; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RATS; RATS, WISTAR; TREATMENT OUTCOME; WARFARIN;

EID: 84864284460     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.016     Document Type: Article

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