Mapping Monoclonal Antibody Structure by 2D 13C NMR at Natural Abundance

Analytical Chemistry

Volumn 87, Issue 7, 2015, Pages 3556-3561

  Arbogast, Luke W ^a   Brinson, Robert G ^a   Marino, John P ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; ESCHERICHIA COLI; ISOTOPES; MAPPING; MONOCLONAL ANTIBODIES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CHINESE HAMSTER OVARY; FINGERPRINT METHOD; FINGERPRINT SPECTRA; ISOTOPIC ABUNDANCES; MONOCLONAL ANTIBODIES (MABS); NONUNIFORM SAMPLING; PRECISE MEASUREMENTS; STRUCTURAL MAPPING;

ANTIBODIES;

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN FC FRAGMENT; MONOCLONAL ANTIBODY;

ANIMAL; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL LINE; CRICETULUS; HAMSTER; NUCLEAR MAGNETIC RESONANCE; PROTEIN CONFORMATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; CHO CELLS; CRICETINAE; CRICETULUS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN FC FRAGMENTS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION;

EID: 84926638538     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac504804m     Document Type: Article

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