Measurement of active site ionization equilibria in the 670 kDa proteasome core particle using methyl-TROSY NMR

Journal of the American Chemical Society

Volumn 135, Issue 25, 2013, Pages 9259-9262

  Velyvis, Algirdas ^a   Kay, Lewis E ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC NUCLEOPHILES; CELLULAR FUNCTION; CORE PARTICLES; DRUG TARGETS; HIGH-RESOLUTION STRUCTURES; MOLECULAR MACHINES; PEPTIDE BONDS; TERMINAL AMINO GROUPS;

PEPTIDES;

CHEMICAL BONDS;

PROTEASOME;

ARTICLE; CELL FUNCTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROGEN BOND; HYDROLYSIS; IONIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT;

CATALYTIC DOMAIN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 84879529913     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja403091c     Document Type: Article

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