Assessment of the three-dimensional structure of recombinant protein therapeutics by NMR fingerprinting: Demonstration on recombinant human granulocyte macrophage-colony stimulation factor

Analytical Chemistry

Volumn 80, Issue 7, 2008, Pages 2623-2627

  Aubin, Yves ^a,b,c,d   Gingras, Geneviève ^a   Sauvé, Simon ^a  

^a HEALTH CANADA   (Canada)

^b CARLETON UNIVERSITY   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; MACROPHAGES; NUCLEAR MAGNETIC RESONANCE; SENSITIVITY ANALYSIS;

RECOMBINANT PROTEIN THERAPEUTICS; THREE-DIMENSIONAL STRUCTURE;

PROTEINS;

RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ARTICLE; CORRELATION ANALYSIS; ESCHERICHIA COLI; HETERONUCLEAR SINGLE QUANTUM COHERENCE; NUCLEAR MAGNETIC RESONANCE; PROTEIN CONFORMATION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; STREPTOMYCES LIVIDANS; STRUCTURE ANALYSIS;

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMAGING, THREE-DIMENSIONAL; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STREPTOMYCES LIVIDANS;

EID: 41849131847     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac7026222     Document Type: Article

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