Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals

Parasites and Vectors

Volumn 8, Issue 1, 2015, Pages

  Arndts, Kathrin ^a   Klarmann Schulz, Ute ^a   Batsa, Linda ^b   Debrah, Alexander Y ^b,c   Epp, Christian ^d   Fimmers, Rolf ^a   Specht, Sabine ^a   Layland, Laura E ^a   Hoerauf, Achim ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b KUMASI CENTRE FOR COLLABORATIVE RESEARCH IN TROPICAL MEDICINE   (Ghana)

^c KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Cytokine; Ivermectin; Microfilariae; MSP 1; Multivariable regression analysis; Onchocerca volvulus; Plasmodium

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 17ALPHA; INTERLEUKIN 5; INTERLEUKIN 6; IVERMECTIN; MEROZOITE SURFACE PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIPARASITIC AGENT; IL17A PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

ADULT; ANTIMICROBIAL THERAPY; ARTICLE; CELL ISOLATION; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; MICROFILARIA (NEMATODE LARVA); ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; PERIPHERAL BLOOD MONONUCLEAR CELL; REPEATED DRUG DOSE; SUPERNATANT; TH17 CELL; ADOLESCENT; ANIMAL; CELLULAR IMMUNITY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PARASITEMIA; PLASMODIUM; UPREGULATION; YOUNG ADULT;

ONCHOCERCA VOLVULUS;

ADOLESCENT; ADULT; ANIMALS; ANTIPARASITIC AGENTS; FEMALE; HUMANS; IMMUNITY, CELLULAR; INTERLEUKIN-17; INTERLEUKIN-6; IVERMECTIN; MALE; MEROZOITE SURFACE PROTEIN 1; MIDDLE AGED; MULTIVARIATE ANALYSIS; ONCHOCERCA VOLVULUS; PARASITEMIA; PLASMODIUM; TH17 CELLS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; YOUNG ADULT;

EID: 84926610240     PISSN: None     EISSN: 17563305     Source Type: Journal    
DOI: 10.1186/s13071-015-0786-5     Document Type: Article

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