Neutrophils play a critical role in the pathogenesis of experimental cerebral malaria

Clinical and Experimental Immunology

Volumn 120, Issue 1, 2000, Pages 125-133

  Chen, L ^a   Zhang, Z H ^a   Sendo, F ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Cerebral malaria; Cytokines; Neutrophils; Plasmodium berghei ANKA; Th1

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MALARIA; CONTROLLED STUDY; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PLASMODIUM BERGHEI; PRIORITY JOURNAL;

EID: 0034024232     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01196.x     Document Type: Article

References (46)

1. Grau GE, Piguet PF, Engers HD, Louis JA, Vassalli P, Lambert PH. L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol 1986; 137:2348-54.
2. Grau GE, Piguet PF, Vassalli P, Lambert PH. Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol Rev 1989; 112:49-70.
3. Grau GE, Taylor TE, Molyneux ME et al. Tumor necrosis factor and disease severity in children with falciparum malaria. New Engl J Med 1989; 320:1586-91.
4. Kern P, Van Hemmer CJDJ, Gruss HJ, Dietrich M. Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. Am J Med 1989; 87:139-43.
5. Kwiatkowski D, Hill AV, Sambou I et al. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 1990; 336:1201-4.
6. Grau GE, Fajardo LF, Piguet PF, Allet B, Lambert PH, Vassalli P. Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 1987; 237:1210-2.
7. Yanez DM, Manning DD, Cooley AJ et al. Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J Immunol 1996; 157:1620-4.
8. Hermsen C, Van de Wiel T, Mommers E, Depletion of CD4+ or CD8+ T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease. Parasitology 1997; 114:7-12.
9. Kudo C, Yamashita T, Araki A et al. Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. I. Inhibition by RP-3 treatment of the priming and effector phases of delayed type hypersensitivity to sheep red blood cells in rats. J Immunol 1993; 150:3728-38.
10. Kudo C, Yamashita T, Terashita M, Sendo F. Modulation of in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. II. Inhibition by RP-3 treatment of mononuclear leukocyte recruitment in delayed-type hypersensitivity to sheep red blood cells in rats. J Immunol 1993; 150:3739-46.
11. Tamura M, Sekiya S, Terashita M, Sendo F. Modulation of the in vivo immune response by selective depletion of neutrophils using a monoclonal antibody, RP-3. III. Enhancement by RP-3 treatment of the anti-sheep red blood cell plaque-forming cell response in rats. J Immunol 1994; 153:1301-8.
12. Terashita M, Kudo C, Yamashita T, Gresser I, Sendo F. Enhancement of delayed-type hypersensitivity to sheep red blood cells in mice by granulocyte colony-stimulating factor administration at the elicitation phase. J Immunol 1996; 156:4638-43.
13. Lloyd AR, Oppenheim JJ. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response. Immunol Today 1992; 13:169-72.
14. Cassatella MA. The production of cytokines by polymorphonuclear neutrophils. Immunol Today 1995; 16:21-26.
15. Cassatella MA, Meda L, Gasperini S, D'Andrea A, Ma X, Trinchieri G. Interleukin-12 production by human polymorphonuclear leukocytes. Eur J Immunol 1995; 25:1-5.
16. Romani L, Mencacci A, Cenci E et al. Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice. J Immunol 1997; 158:5349-56.
17. Conlan JW, North RJ. Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody. J Exp Med 1994; 179:259-68.
18. Czuprynski CJ, Brown JF, Maroushek N, Wagner RD, Steinberg H. Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection. J Immunol 1994; 152:1836-46.
19. Czuprynski CJ, Brown JF, Wagner RD, Steinberg H. Administration of antigranulocyte monoclonal antibody RB6-8C5 prevents expression of acquired resistance to Listeria monocytogenes infection in previously immunized mice. Infect Immun 1994; 62:5161-3.
20. Rogers HW, Unanue ER. Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice. Infect Immun 1993; 61:5090-6.
21. Rakhmilevich AL. Neutrophils are essential for resolution of primary and secondary infection with Listeria monocytogenes. J Leuk Biol 1995; 57:827-31.
22. Benavides GR, Hubby B, Grosse WM, McGraw RA, Tarleton RL. Construction and use of a multi-competitor gene for quantitative RT-PCR using existing primer sets. J Immunol Methods 1995; 181:145-56.
23. Kopf M, Brombacher F, Kohler G et al. IL-4-deficient Balb/c mice resist infection with Leishmania major. J Exp Med 1996; 184:1127-36.
24. de Kossodo S, Grau GE. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J Immunol 1993; 151:4811-20.
25. Rudin W, Eugster HP, Bordmann G et al. Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response. Am J Pathol 1997; 150:257-66.
26. Rudin W, Favre N, Bordmann G, Ryffel B. Interferon-gamma is essential for the development of cerebral malaria. Eur J Immunol 1997; 27:810-5.
27. Jennings VM, Actor JK, Lal AA, Hunter RL. Cytokine profile suggesting that murine cerebral malaria is an encephalitis. Infect Immun 1997; 65:4883-7.
28. Senaldi G, Vesin C, Chang R, Grau GE, Piguet PF. Role of polymorphonuclear neutrophil leukocytes and their integrin CD1 la (LFA-1) in the pathogenesis of severe murine malaria. Infect Immun 1994; 62:1144-9.
29. Kasama T, Strieter RM, Standiford TJ, Burdick MD, Kunkel SL. Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1 alpha. J Exp Med 1993; 178:63-72.
30. Kasama T, Strieter RM, Lukacs NW, Burdick MD, Kunkel SL. Regulation of neutrophil-derived chemokine expression by IL-10. J Immunol 1994; 152:3559-69.
31. Bliss SK, Marshall AJ, Zhang Y, Denkers EC. Human polymorphonuclear leukocytes produce IL-12, TNF-α, and the chemokines macrophage-inflammatory protein-1α and -1β in response to Toxoplasma gondii antigens. J Immunol 1999; 162:7369-75.
32. Gasperini S, Marchi M, Calzetti F et al. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (1-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J Immunol 1999; 162:4928-37.
33. Loetscher P, Uguccioni M, Bordoli L et al. CCR5 is characteristic of Th1 lymphocytes. Nature 1998; 391:344-5.
34. Qin S, Rottman JB, Myers P et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest 1998; 101:746-54.
35. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998; 187:875-83.
36. Siveke JT, Hamann A. T helper 1 and T helper 2 cells respond differentially to chemokines. J Immunol 1998; 160:550-4.
37. Bonecchi R, Bianchi G, Bordignon PP et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med 1998; 187:129-34.
38. Medana IM, Hunt NH, Chaudhri G. Tumor necrosis factor-alpha expression in the brain during fatal murine cerebral malaria: evidence for production by microglia and astrocytes. Am J Pathol 1997; 150:1473-86.
39. Medana IM, Hunt NH, Chan LT. Early activation of microglia in the pathogenesis of fatal murine cerebral malaria. Glia 1997; 19:91-103.
40. Clark IA, Ilschner S, MacMicking JD, Cowden WB. TNF and Plasmodium berghei ANKA-induced cerebral malaria. Immunol Letters 1990; 25:195-8.
41. Shaffer N, Grau GE, Hedberg K et al. Tumor necrosis factor and severe malaria. J Infect Dis 1991; 163:96-101.
42. Lou J, Gasche Y, Zheng L et al. Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria. Eur J Immunol 1998; 28:3989-4000.
43. Borst P, Bitter W, Van McCulloch RLF, Rudenko G. Antigenic variation in malaria. Cell 1995; 82:1-4.
44. Sato T, Midorikawa Y, Yamashita T, Araki A, Sendo F. The neutrophil as an information transmitter in tumor inhibition by a streptococcal biological response modifier, OK-432. Cancer Immunol Immunother 1996; 43:77-86.
45. Amodu OK, Adeyemo AA, Olumese PE, Gbadegesin RA. Intraleucocytic malaria pigment and clinical severity of malaria in children. Trans R Soc Trop Med Hyg 1998; 92:54-56.
46. Pukrittayakamee S, Clemens R, Pramoolsinsap C et al. Polymorphonuclear leucocyte elastase in Plasmodium falciparum malaria. Trans R Soc Trop Med Hyg 1992; 86:598-601.