Enantioselective desymmetrization of prochiral cyclohexanones by organocatalytic intramolecular michael additions to α,β-unsaturated esters

Angewandte Chemie - International Edition

Volumn 54, Issue 16, 2015, Pages 4899-4903

  Gammack Yamagata, Adam D ^a   Datta, Swarup ^a   Jackson, Kelvin E ^a   Stegbauer, Linus ^a   Paton, Robert S ^a   Dixon, Darren J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

desymmetrization; enamine catalysis; Michael addition; organocatalysis; quantum chemical calculations

Indexed keywords

ADDITION REACTIONS; CATALYSIS; CATALYST SELECTIVITY; CATALYSTS; CHEMICAL BONDS; ESTERIFICATION; ESTERS; QUANTUM CHEMISTRY; REACTION KINETICS; SYNTHESIS (CHEMICAL);

DESYM-METRIZATION; ENAMINES; MICHAEL ADDITIONS; ORGANOCATALYSIS; QUANTUM CHEMICAL CALCULATIONS;

ENANTIOSELECTIVITY;

AMINE; BICYCLO(3.3.1)NONANE; BRIDGED BICYCLO COMPOUNDS; CYCLOHEXANONE; CYCLOHEXANONE DERIVATIVE; ESTER; HETEROCYCLIC COMPOUND;

CATALYSIS; CHEMISTRY; CONFORMATION; CYCLIZATION; QUANTUM THEORY; STEREOISOMERISM; SYNTHESIS; THERMODYNAMICS;

AMINES; AZA COMPOUNDS; BRIDGED BICYCLO COMPOUNDS; CATALYSIS; CYCLIZATION; CYCLOHEXANONES; ESTERS; MOLECULAR CONFORMATION; QUANTUM THEORY; STEREOISOMERISM; THERMODYNAMICS;

EID: 84926500098     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201411924     Document Type: Article

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