Organocatalyzed asymmetric synthesis of morphans

Organic Letters

Volumn 15, Issue 10, 2013, Pages 2458-2461

  Bradshaw, Ben ^a   Parra, Claudio ^a   Bonjoch, Josep ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCYCLIC COMPOUND;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS;

AZA COMPOUNDS; CATALYSIS; CYCLIZATION; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 84877917632     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol400926p     Document Type: Article

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28. Keto esters 3 were prepared by coupling the correpsponding carboxylic acid with Meldrum's acid using DCC, followed by refluxing in t -BuOH. For an early use of this methdology, see: Li, B.; Franck, R. W: Bioorg. Med. Chem. Lett. 1999, 9, 2629-2634
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