-
1
-
-
74249092481
-
Biomarkers of angiogenesis and their role in the development of VEGF inhibitors
-
Murukesh, N., Dive, C. & Jayson, G.C. Biomarkers of angiogenesis and their role in the development of VEGF inhibitors. Br. J. Cancer 102, 8-18 (2010).
-
(2010)
Br. J. Cancer
, vol.102
, pp. 8-18
-
-
Murukesh, N.1
Dive, C.2
Jayson, G.C.3
-
2
-
-
46949084994
-
Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: Tools or decorations?
-
Sessa, C., Guibal, A., Del Conte, G. & Rüegg, C. Biomarkers of angiogenesis for the development of antiangiogenic therapies in oncology: tools or decorations? Nat. Clin. Pract. Oncol. 5, 378-391 (2008).
-
(2008)
Nat. Clin. Pract. Oncol.
, vol.5
, pp. 378-391
-
-
Sessa, C.1
Guibal, A.2
Del Conte, G.3
Rüegg, C.4
-
3
-
-
82155203054
-
Biomarkers predicting tumor response and evasion to anti-angiogenic therapy
-
Jahangiri, A. & Aghi, M.K. Biomarkers predicting tumor response and evasion to anti-angiogenic therapy. Biochim. Biophys. Acta 1825, 86-100 (2012).
-
Biochim. Biophys. Acta
, pp. 86-100
-
-
Jahangiri, A.1
Aghi, M.K.2
-
4
-
-
67650380136
-
Biomarkers of response and resistance to antiangiogenic therapy
-
Jain, R.K. et al. Biomarkers of response and resistance to antiangiogenic therapy. Nat. Rev. Clin. Oncol. 6, 327-338 (2009).
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 327-338
-
-
Jain, R.K.1
-
5
-
-
84878878984
-
Can we identify predictive biomarkers for antiangiogenic therapy of cancer using mathematical modeling?
-
Duda, D.G., Munn, L.L. & Jain, R.K. Can we identify predictive biomarkers for antiangiogenic therapy of cancer using mathematical modeling? J. Natl. Cancer Inst. 105, 762-765 (2013).
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 762-765
-
-
Duda, D.G.1
Munn, L.L.2
Jain, R.K.3
-
6
-
-
36749052895
-
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor effcacy
-
Copyright (2007) National Academy of Sciences, U.S.A
-
Ebos, J.M., Lee, C.R., Christensen, J.G., Mutsaers, A.J. & Kerbel, R.S. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor effcacy. Proc. Natl. Acad. Sci. U.S.A. 104, 17069-17074 (2007). Copyright (2007) National Academy of Sciences, U.S.A.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 17069-17074
-
-
Ebos, J.M.1
Lee, C.R.2
Christensen, J.G.3
Mutsaers, A.J.4
Kerbel, R.S.5
-
7
-
-
77951499421
-
Pharmacokinetic/pharmacodynamic modeling of biomarker response to sunitinib in healthy volunteers
-
Lindauer, A. et al. Pharmacokinetic/pharmacodynamic modeling of biomarker response to sunitinib in healthy volunteers. Clin. Pharmacol. Ther. 87, 601-608 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, pp. 601-608
-
-
Lindauer, A.1
-
8
-
-
84876567464
-
Systems pharmacology for drug discovery and development: Paradigm shift or fash in the pan?
-
Vicini, P. & van der Graaf, P.H. Systems pharmacology for drug discovery and development: paradigm shift or fash in the pan? Clin. Pharmacol. Ther. 93, 379-381 (2013).
-
(2013)
Clin. Pharmacol. Ther.
, vol.93
, pp. 379-381
-
-
Vicini, P.1
Van Der Graaf, P.H.2
-
9
-
-
79959900575
-
Systems pharmacology: Bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development
-
van der Graaf, P.H. & Benson, N. Systems pharmacology: bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development. Pharm. Res. 28, 1460-1464 (2011).
-
(2011)
Pharm. Res.
, vol.28
, pp. 1460-1464
-
-
Van Der Graaf, P.H.1
Benson, N.2
-
10
-
-
63849092341
-
Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: Clinical outcomes and plasma angiogenesis markers
-
Kontovinis, L.F., Papazisis, K.T., Touplikioti, P. , Andreadis, C., Mouratidou, D. & Kortsaris, A.H. Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers. BMC Cancer 9, 82 (2009).
-
(2009)
BMC Cancer
, vol.9
, pp. 82
-
-
Kontovinis, L.F.1
Papazisis, K.T.2
Touplikioti, P.3
Andreadis, C.4
Mouratidou, D.5
Kortsaris, A.H.6
-
11
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers, G. & Hanahan, D. Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8, 592-603 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
12
-
-
77954668887
-
Angiogenesis inhibitors: Current strategies and future prospects
-
Cook, K.M. & Figg, W.D. Angiogenesis inhibitors: current strategies and future prospects. CA. Cancer J. Clin. 60, 222-243 (2010).
-
(2010)
CA. Cancer J. Clin.
, vol.60
, pp. 222-243
-
-
Cook, K.M.1
Figg, W.D.2
-
13
-
-
84880886028
-
Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks
-
Wagner, J.P. et al. Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks. Sci. Signal. 6, ra58 (2013).
-
(2013)
Sci. Signal.
, vol.6
, pp. ra58
-
-
Wagner, J.P.1
-
14
-
-
84884162850
-
Computational modeling of ERBB2-amplifed breast cancer identifes combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors
-
Kirouac, D.C. et al. Computational modeling of ERBB2-amplifed breast cancer identifes combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors. Sci. Signal. 6, ra68 (2013).
-
(2013)
Sci. Signal.
, vol.6
, pp. ra68
-
-
Kirouac, D.C.1
-
15
-
-
36749040908
-
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting effcacious angiogenic blockade
-
Rudge, J.S. et al. VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting effcacious angiogenic blockade. Proc. Natl. Acad. Sci. U.S.A. 104, 18363-18370 (2007).
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 18363-18370
-
-
Rudge, J.S.1
-
16
-
-
33750286135
-
The multifaceted circulating endothelial cell in cancer: Towards marker and target identifcation
-
Bertolini, F. , Shaked, Y. , Mancuso, P. & Kerbel, R.S. The multifaceted circulating endothelial cell in cancer: towards marker and target identifcation. Nat. Rev. Cancer 6, 835-845 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 835-845
-
-
Bertolini, F.1
Shaked, Y.2
Mancuso, P.3
Kerbel, R.S.4
-
17
-
-
20044373242
-
Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy
-
Manenti, L. et al. Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy. Mol. Cancer Ther. 4, 715-725 (2005).
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 715-725
-
-
Manenti, L.1
-
18
-
-
80054993340
-
Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cell cancer
-
Yuasa, T. , Takahashi, S., Hatake, K., Yonese, J. & Fukui, I. Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cell cancer. Cancer Sci. 102, 1949-1957 (2011).
-
(2011)
Cancer Sci.
, vol.102
, pp. 1949-1957
-
-
Yuasa, T.1
Takahashi, S.2
Hatake, K.3
Yonese, J.4
Fukui, I.5
-
19
-
-
81455150067
-
Mathematical model identifes blood biomarker-based early cancer detection strategies and limitations
-
Hori, S.S. & Gambhir, S.S. Mathematical model identifes blood biomarker-based early cancer detection strategies and limitations. Sci. Transl. Med. 3, 109ra116 (2011).
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 109ra116
-
-
Hori, S.S.1
Gambhir, S.S.2
-
20
-
-
79953077853
-
Moving towards dose individualization of tyrosine kinase inhibitors
-
Klümpen, H.J., Samer, C.F., Mathijssen, R.H., Schellens, J.H. & Gurney, H. Moving towards dose individualization of tyrosine kinase inhibitors. Cancer Treat. Rev. 37, 251-260 (2011).
-
(2011)
Cancer Treat. Rev.
, vol.37
, pp. 251-260
-
-
Klümpen, H.J.1
Samer, C.F.2
Mathijssen, R.H.3
Schellens, J.H.4
Gurney, H.5
-
21
-
-
84891785804
-
PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST
-
Hansson, E.K. et al. PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST. CPT. Pharmacometrics Syst. Pharmacol. 2, e84 (2013).
-
(2013)
CPT. Pharmacometrics Syst. Pharmacol.
, vol.2
, pp. e84
-
-
Hansson, E.K.1
-
22
-
-
0347363488
-
Angiogenic growth factor response to acute systemic exercise in human skeletal muscle
-
Gavin, T.P., Robinson, C.B., Yeager, R.C., England, J.A., Nifong, L.W. & Hickner, R.C. Angiogenic growth factor response to acute systemic exercise in human skeletal muscle. J. Appl. Physiol. 96, 19-24 (2004).
-
(2004)
J. Appl. Physiol.
, vol.96
, pp. 19-24
-
-
Gavin, T.P.1
Robinson, C.B.2
Yeager, R.C.3
England, J.A.4
Nifong, L.W.5
Hickner, R.C.6
-
23
-
-
65049090261
-
Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: Correlation with clinical parameters and outcome
-
Mouawad, R., Spano, J.P., Comperat, E., Capron, F. & Khayat, D. Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcome. Eur. J. Cancer 45, 1407-1414 (2009).
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 1407-1414
-
-
Mouawad, R.1
Spano, J.P.2
Comperat, E.3
Capron, F.4
Khayat, D.5
-
24
-
-
79960590467
-
Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib
-
Harmon, C.S. et al. Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J. Transl. Med. 9, 120 (2011).
-
(2011)
J. Transl. Med.
, vol.9
, pp. 120
-
-
Harmon, C.S.1
-
25
-
-
34547779489
-
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: Modulation of VEGF and VEGF-related proteins
-
Deprimo, S.E. et al. Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins. J. Transl. Med. 5, 32 (2007).
-
(2007)
J. Transl. Med.
, vol.5
, pp. 32
-
-
Deprimo, S.E.1
-
26
-
-
84859880607
-
Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma
-
Llovet, J.M., Peña, C.E., Lathia, C.D., Shan, M., Meinhardt, G. & Bruix, J.; SHARP Investigators Study Group. Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin. Cancer Res. 18, 2290-2300 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 2290-2300
-
-
Llovet, J.M.1
Peña, C.E.2
Lathia, C.D.3
Shan, M.4
Meinhardt, G.5
Bruix, J.6
-
27
-
-
70249097380
-
Sorafenib for treatment of renal cell carcinoma: Final effcacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
-
Escudier, B. et al. Sorafenib for treatment of renal cell carcinoma: Final effcacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J. Clin. Oncol. 27, 3312-3318 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3312-3318
-
-
Escudier, B.1
-
28
-
-
84876417691
-
Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy
-
Jürgensmeier, J.M. et al. Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy. Br. J. Cancer 108, 1316-1323 (2013).
-
(2013)
Br. J. Cancer
, vol.108
, pp. 1316-1323
-
-
Jürgensmeier, J.M.1
-
29
-
-
49249087039
-
Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma
-
Rini, B.I. et al. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J. Clin. Oncol. 26, 3743-3748 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 3743-3748
-
-
Rini, B.I.1
-
30
-
-
84886675563
-
Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease
-
Goel, S., Wong, A.H. & Jain, R.K. Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease. Cold Spring Harb. Perspect. Med. 2, a006486 (2012).
-
(2012)
Cold Spring Harb. Perspect. Med.
, vol.2
, pp. a006486
-
-
Goel, S.1
Wong, A.H.2
Jain, R.K.3
-
31
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain, R.K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307, 58-62 (2005).
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
32
-
-
84878877091
-
Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: Systems biology predictions
-
Finley, S.D. & Popel, A.S. Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions. J. Natl. Cancer Inst. 105, 802-811 (2013).
-
(2013)
J. Natl. Cancer Inst.
, vol.105
, pp. 802-811
-
-
Finley, S.D.1
Popel, A.S.2
-
33
-
-
79957925832
-
Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer
-
Tugues, S., Koch, S., Gualandi, L., Li, X. & Claesson-Welsh, L. Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer. Mol. Aspects Med. 32, 88-111 (2011).
-
(2011)
Mol. Aspects Med.
, vol.32
, pp. 88-111
-
-
Tugues, S.1
Koch, S.2
Gualandi, L.3
Li, X.4
Claesson-Welsh, L.5
-
34
-
-
84884306439
-
Computational model of VEGFR2 pathway to ERK activation and modulation through receptor traffcking
-
Tan, W.H., Popel, A.S. & Mac Gabhann, F. Computational model of VEGFR2 pathway to ERK activation and modulation through receptor traffcking. Cell. Signal. 25, 2496-2510 (2013).
-
(2013)
Cell. Signal.
, vol.25
, pp. 2496-2510
-
-
Tan, W.H.1
Popel, A.S.2
Mac Gabhann, F.3
-
35
-
-
10644279947
-
Vascular endothelial growth factor and angiogenesis
-
Hoeben, A., Landuyt, B., Highley, M.S., Wildiers, H., Van Oosterom, A.T. & De Bruijn, E.A. Vascular endothelial growth factor and angiogenesis. Pharmacol. Rev. 56, 549-580 (2004).
-
(2004)
Pharmacol. Rev.
, vol.56
, pp. 549-580
-
-
Hoeben, A.1
Landuyt, B.2
Highley, M.S.3
Wildiers, H.4
Van Oosterom, A.T.5
De Bruijn, E.A.6
-
36
-
-
0036009760
-
VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
-
Soker, S., Miao, H.Q., Nomi, M., Takashima, S. & Klagsbrun, M. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J. Cell. Biochem. 85, 357-368 (2002).
-
(2002)
J. Cell. Biochem.
, vol.85
, pp. 357-368
-
-
Soker, S.1
Miao, H.Q.2
Nomi, M.3
Takashima, S.4
Klagsbrun, M.5
-
37
-
-
0030050025
-
Flt-1 but not KDR/ Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor
-
Sawano, A., Takahashi, T., Yamaguchi, S., Aonuma, M. & Shibuya, M. Flt-1 but not KDR/ Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor. Cell Growth Differ. 7, 213-221 (1996).
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 213-221
-
-
Sawano, A.1
Takahashi, T.2
Yamaguchi, S.3
Aonuma, M.4
Shibuya, M.5
-
38
-
-
84868618639
-
Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies
-
Shibuya, M. Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies. Genes Cancer 2, 1097-1105 (2011).
-
(2011)
Genes Cancer
, vol.2
, pp. 1097-1105
-
-
Shibuya, M.1
-
39
-
-
84865129521
-
Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
-
Papadopoulos, N. et al. Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab. Angiogenesis 15, 171-185 (2012).
-
(2012)
Angiogenesis
, vol.15
, pp. 171-185
-
-
Papadopoulos, N.1
-
40
-
-
84891090406
-
Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
-
Finley, S.D., Dhar, M. & Popel, A.S. Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice. Front. Oncol. 3, 196 (2013).
-
(2013)
Front. Oncol.
, vol.3
, Issue.196
-
-
Finley, S.D.1
Dhar, M.2
Popel, A.S.3
-
41
-
-
78649952814
-
Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model
-
Stefanini, M.O., Wu, F.T., Mac Gabhann, F. & Popel, A.S. Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model. Cancer Res. 70, 9886-9894 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 9886-9894
-
-
Stefanini, M.O.1
Wu, F.T.2
Mac Gabhann, F.3
Popel, A.S.4
-
42
-
-
84902530538
-
A General Network Pharmacodynamic ModelBased Design Pipeline for Customized Cancer Therapy Applied to the VEGFR Pathway
-
Zhang, X.Y., Birtwistle, M.R. & Gallo, J.M. A General Network Pharmacodynamic ModelBased Design Pipeline for Customized Cancer Therapy Applied to the VEGFR Pathway. CPT. Pharmacometrics Syst. Pharmacol. 3, e92 (2014).
-
(2014)
CPT. Pharmacometrics Syst. Pharmacol.
, vol.3
, pp. e92
-
-
Zhang, X.Y.1
Birtwistle, M.R.2
Gallo, J.M.3
-
43
-
-
84896765551
-
Evaluating systems pharmacology models is different from evaluating standard pharmacokinetic-pharmacodynamic models
-
Agoram, B. Evaluating systems pharmacology models is different from evaluating standard pharmacokinetic-pharmacodynamic models. CPT. Pharmacometrics Syst. Pharmacol. 3, e101 (2014).
-
(2014)
CPT. Pharmacometrics Syst. Pharmacol.
, vol.3
, pp. e101
-
-
Agoram, B.1
-
44
-
-
0004062826
-
-
Biomedical Simulations Resource, Los Angeles
-
D'Argenio, D.Z., Schumitzky, A. & Wang, X. ADAPT 5 User's Guide: Pharmacokinetic/ Pharmacodynamic Systems Analysis Software (Biomedical Simulations Resource, Los Angeles, 2009).
-
(2009)
ADAPT 5 User's Guide: Pharmacokinetic/ Pharmacodynamic Systems Analysis Software
-
-
D'Argenio, D.Z.1
Schumitzky, A.2
Wang, X.3
-
45
-
-
84857399736
-
Pharmacokinetics, distribution, and metabolism of [14C]sunitinib in rats, monkeys, and humans
-
Speed, B. et al. Pharmacokinetics, distribution, and metabolism of [14C]sunitinib in rats, monkeys, and humans. Drug Metab. Dispos. 40, 539-555 (2012).
-
(2012)
Drug Metab. Dispos.
, vol.40
, pp. 539-555
-
-
Speed, B.1
-
46
-
-
65249087328
-
A population pharmacokinetic meta-analysis of sunitinib malate (SU11248) and its primary metabolite (SU12662) in healthy volunteers and oncology patients
-
Houk, B.E., Bello, C.L., Kang, D. & Amantea, M. A population pharmacokinetic meta-analysis of sunitinib malate (SU11248) and its primary metabolite (SU12662) in healthy volunteers and oncology patients. Clin. Cancer Res. 15, 2497-2506 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2497-2506
-
-
Houk, B.E.1
Bello, C.L.2
Kang, D.3
Amantea, M.4
-
47
-
-
0034832459
-
Pharmacodynamic modeling of time-dependent transduction systems
-
Mager, D.E. & Jusko, W.J. Pharmacodynamic modeling of time-dependent transduction systems. Clin. Pharmacol. Ther. 70, 210-216 (2001).
-
(2001)
Clin. Pharmacol. Ther.
, vol.70
, pp. 210-216
-
-
Mager, D.E.1
Jusko, W.J.2
-
48
-
-
84877926385
-
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth after administration of an anti-angiogenic agent, bevacizumab, as single-agent and combination therapy in tumor xenografts
-
Rocchetti, M. et al. Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth after administration of an anti-angiogenic agent, bevacizumab, as single-agent and combination therapy in tumor xenografts. Cancer Chemother. Pharmacol. 71, 1147-1157 (2013).
-
(2013)
Cancer Chemother. Pharmacol.
, vol.71
, pp. 1147-1157
-
-
Rocchetti, M.1
-
49
-
-
0842282616
-
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents
-
Simeoni, M. et al. Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents. Cancer Res. 64, 1094-1101 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 1094-1101
-
-
Simeoni, M.1
-
50
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer, E.A. et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur. J. Cancer 45, 228-247 (2009).
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
|