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Volumn 93, Issue 5, 2013, Pages 379-381

Systems pharmacology for drug discovery and development: Paradigm shift or flash in the pan?

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DEVELOPMENT; HUMAN; INFORMATION PROCESSING; PRIORITY JOURNAL; PROCEDURES; QUANTITATIVE ANALYSIS; REVIEW; SIMULATION; SYSTEMS PHARMACOLOGY;

EID: 84876567464     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2013.40     Document Type: Review
Times cited : (96)

References (11)
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    • A mechanistic, model-based approach to safety assessment in clinical development
    • Lippert, J. et al. A mechanistic, model-based approach to safety assessment in clinical development. CPT: Pharmacomet. Syst. Pharmacol. 1, e13 (2012).
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    • Lippert, J.1
  • 7
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    • Has the time come for predictive computer modeling in CNS drug discovery and development?
    • Geerts, H., Spiros, A., Roberts, P. & Carr, R. Has the time come for predictive computer modeling in CNS drug discovery and development? CPT: Pharmacomet. Syst. Pharmacol. 1, e16 (2012).
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  • 8
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    • Multiscale kinetic modeling of liposomal doxorubicin delivery quantifies the role of tumor and drug-specific parameters in local delivery to tumors
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    • (2012) CPT: Pharmacomet. Syst. Pharmacol. , vol.1
    • Hendriks, B.S.1
  • 9
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    • Predicting nonlinear changes in bone mineral density over time using a multiscale systems pharmacology model
    • Peterson, M.C. & Riggs, M.M. Predicting nonlinear changes in bone mineral density over time using a multiscale systems pharmacology model. CPT: Pharmacomet. Syst. Pharmacol. 1, e14 (2012).
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  • 10
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    • Integrated pharmacometrics and systems pharmacology model-based analyses to guide GnRH receptor modulator development for management of endometriosis
    • Riggs, M.M., Bennetts, M., van der Graaf, P.H. & Martin, S.W. Integrated pharmacometrics and systems pharmacology model-based analyses to guide GnRH receptor modulator development for management of endometriosis. CPT: Pharmacomet. Syst. Pharmacol. 1, e11 (2012).
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    • Morgan, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.