Quantitative proteomics reveals a novel role of karyopherin alpha 2 in cell migration through the regulation of vimentin-perk protein complex levels in lung Cancer

Journal of Proteome Research

Volumn 14, Issue 4, 2015, Pages 1739-1751

  Wang, Chun I ^a   Wang, Chih Liang ^b   Wu, Yi Cheng ^c   Feng, Hsiang Pu ^a   Liu, Pei Jun ^a   Chang, Yu Sun ^a   Yu, Jau Song ^a   Yu, Chia Jung ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b Department of Thoracic Medicine   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Invasiveness; KPNA2; Lung cancer; pErk; Vimentin

Indexed keywords

ACTIN; BETA TUBULIN; CYTOKERATIN 18; CYTOKERATIN 8; HETERODIMER; KARYOPHERIN ALPHA; KARYOPHERIN ALPHA 2; MITOGEN ACTIVATED PROTEIN KINASE; PLECTIN; TUBULIN; UNCLASSIFIED DRUG; VIMENTIN; KPNA2 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX;

ADENOCARCINOMA CELL LINE; ADULT; AGED; ANALYTIC METHOD; ARTICLE; CANCER GROWTH; CANCER TISSUE; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSKELETON; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; LUNG ADENOCARCINOMA; LUNG CANCER; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEOMICS; QUANTITATIVE ANALYSIS; STABLE ISOTOPE LABELING WITH AMINO ACID IN CELL CULTURE; TUMOR INVASION; UPREGULATION; VERY ELDERLY; CELL MOTION; GENETICS; LUNG TUMOR; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

ALPHA KARYOPHERINS; CELL MOVEMENT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LUNG NEOPLASMS; MULTIPROTEIN COMPLEXES; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION; VIMENTIN;

EID: 84926490613     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr501097a     Document Type: Article

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