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Volumn 34, Issue 1, 2015, Pages

MiR-223 promotes the cisplatin resistance of human gastric cancer cells via regulating cell cycle by targeting FBXW7

Author keywords

Cisplatin resistance; FBXW7; Gastric cancer; miR 223

Indexed keywords

CISPLATIN; FBXW7 PROTEIN; MICRORNA 223; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; MESSENGER RNA; MICRORNA; MIRN223 MICRORNA, HUMAN; UBIQUITIN PROTEIN LIGASE;

EID: 84926457197     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-015-0145-6     Document Type: Article
Times cited : (104)

References (38)
  • 2
    • 84885382705 scopus 로고    scopus 로고
    • Socioeconomic position and incidence of gastric cancer: A systematic review and meta-analysis
    • 23929615
    • Uthman OA, Jadidi E, Moradi T. Socioeconomic position and incidence of gastric cancer: a systematic review and meta-analysis. J Epidemiol Community Health. 2013;67:854-60.
    • (2013) J Epidemiol Community Health , vol.67 , pp. 854-860
    • Uthman, O.A.1    Jadidi, E.2    Moradi, T.3
  • 3
    • 84879417823 scopus 로고    scopus 로고
    • Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance
    • 1:CAS:528:DC%2BC38XhtFCrt7nM 22869148
    • Chell V, Balmanno K, Little AS, Wilson M, Andrews S, Blockley L, et al. Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance. Oncogene. 2013;32:3059-70.
    • (2013) Oncogene , vol.32 , pp. 3059-3070
    • Chell, V.1    Balmanno, K.2    Little, A.S.3    Wilson, M.4    Andrews, S.5    Blockley, L.6
  • 4
    • 79551559942 scopus 로고    scopus 로고
    • Multiple mutations and bypass mechanisms can contribute to development of acquired resistance to MET inhibitors
    • 3208270 1:CAS:528:DC%2BC3MXhsVCisr0%3D 21266357
    • Qi J, McTigue MA, Rogers A, Lifshits E, Christensen JG, Jänne PA, et al. Multiple mutations and bypass mechanisms can contribute to development of acquired resistance to MET inhibitors. Cancer Res. 2011;71:1081-91.
    • (2011) Cancer Res , vol.71 , pp. 1081-1091
    • Qi, J.1    McTigue, M.A.2    Rogers, A.3    Lifshits, E.4    Christensen, J.G.5    Jänne, P.A.6
  • 5
    • 38849171927 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers
    • 1:CAS:528:DC%2BD1cXhsFOms74%3D 18172554
    • Zudaire E, Cuesta N, Murty V, Woodson K, Adams L, Gonzalez N, et al. The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers. J Clin Invest. 2008;118:640-50.
    • (2008) J Clin Invest , vol.118 , pp. 640-650
    • Zudaire, E.1    Cuesta, N.2    Murty, V.3    Woodson, K.4    Adams, L.5    Gonzalez, N.6
  • 6
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • 3794896 1:CAS:528:DC%2BD1MXhs1Kiuro%3D 19167326
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136:215-33.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 7
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • 3351105 1:CAS:528:DC%2BC38Xmt1Grtb0%3D 22541426
    • Ebert MS, Sharp PA. Roles for microRNAs in conferring robustness to biological processes. Cell. 2012;149:515-24.
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 8
    • 84897128298 scopus 로고    scopus 로고
    • The noncoding RNA revolution-trashing old rules to forge new ones
    • 1:CAS:528:DC%2BC2cXmtVCktLo%3D 24679528
    • Cech TR, Steitz JA. The noncoding RNA revolution-trashing old rules to forge new ones. Cell. 2014;157:77-94.
    • (2014) Cell , vol.157 , pp. 77-94
    • Cech, T.R.1    Steitz, J.A.2
  • 9
    • 84879457821 scopus 로고    scopus 로고
    • Let-7b expression determines response to chemotherapy through the regulation of cyclin D1 in glioblastoma
    • 3716992 23806108
    • Guo Y, Yan K, Fang J, Qu Q, Zhou M, Chen F. Let-7b expression determines response to chemotherapy through the regulation of cyclin D1 in glioblastoma. J Exp Clin Cancer Res. 2013;32:41.
    • (2013) J Exp Clin Cancer Res , vol.32 , pp. 41
    • Guo, Y.1    Yan, K.2    Fang, J.3    Qu, Q.4    Zhou, M.5    Chen, F.6
  • 10
    • 84883488449 scopus 로고    scopus 로고
    • MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3
    • 1:CAS:528:DC%2BC3sXht12is7vP 23932924
    • Zhang Y, Lu Q, Cai X. MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3. FEBS Lett. 2013;587:3069-75.
    • (2013) FEBS Lett , vol.587 , pp. 3069-3075
    • Zhang, Y.1    Lu, Q.2    Cai, X.3
  • 11
    • 84908022850 scopus 로고    scopus 로고
    • MiR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1
    • 1:CAS:528:DC%2BC3sXhtFOrs7%2FM 23893241
    • Shang Y, Zhang Z, Liu Z, Feng B, Ren G, Li K, et al. miR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1. Oncogene. 2014;33:3267-76.
    • (2014) Oncogene , vol.33 , pp. 3267-3276
    • Shang, Y.1    Zhang, Z.2    Liu, Z.3    Feng, B.4    Ren, G.5    Li, K.6
  • 12
    • 84897971554 scopus 로고    scopus 로고
    • MiR-33a is up-regulated in chemoresistant osteosarcoma and promotes osteosarcoma cell resistance to cisplatin by down-regulating TWIST
    • 3974149 1:CAS:528:DC%2BC2MXhslSrtLc%3D 24468065
    • Zhou Y, Huang Z, Wu S, Zang X, Liu M, Shi J. miR-33a is up-regulated in chemoresistant osteosarcoma and promotes osteosarcoma cell resistance to cisplatin by down-regulating TWIST. J Exp Clin Cancer Res. 2014;33:12.
    • (2014) J Exp Clin Cancer Res , vol.33 , pp. 12
    • Zhou, Y.1    Huang, Z.2    Wu, S.3    Zang, X.4    Liu, M.5    Shi, J.6
  • 13
    • 84920935939 scopus 로고    scopus 로고
    • The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway
    • doi:10.1002/ijc.29168
    • Eto K, Iwatsuki M, Watanabe M, Ishimoto T, Ida S, Imamura Y, et al.: The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway. Int J Cancer 2014, doi:10.1002/ijc.29168.
    • (2014) Int J Cancer
    • Eto, K.1    Iwatsuki, M.2    Watanabe, M.3    Ishimoto, T.4    Ida, S.5    Imamura, Y.6
  • 14
    • 44949249814 scopus 로고    scopus 로고
    • MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • 1:CAS:528:DC%2BD1cXnsF2jtrw%3D 18449891
    • Xia L, Zhang D, Du R, Pan Y, Zhao L, Sun S, et al. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer. 2008;123:372-9.
    • (2008) Int J Cancer , vol.123 , pp. 372-379
    • Xia, L.1    Zhang, D.2    Du, R.3    Pan, Y.4    Zhao, L.5    Sun, S.6
  • 15
    • 84906254304 scopus 로고    scopus 로고
    • F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a
    • 25115392
    • Zhang X, Kong Y, Xu X, Xing H, Zhang Y, Han F, et al. F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a. Oncotarget. 2014;5:6178-90.
    • (2014) Oncotarget , vol.5 , pp. 6178-6190
    • Zhang, X.1    Kong, Y.2    Xu, X.3    Xing, H.4    Zhang, Y.5    Han, F.6
  • 16
    • 84887020278 scopus 로고    scopus 로고
    • Identification of serum miRNAs as novel non-invasive biomarkers for detection of high risk for early gastric cancer
    • 3817334 1:CAS:528:DC%2BC3sXhsFymsLzI 24104965
    • Shiotani A, Murao T, Kimura Y, Matsumoto H, Kamada T, Kusunoki H, et al. Identification of serum miRNAs as novel non-invasive biomarkers for detection of high risk for early gastric cancer. Br J Cancer. 2013;109:2323-30.
    • (2013) Br J Cancer , vol.109 , pp. 2323-2330
    • Shiotani, A.1    Murao, T.2    Kimura, Y.3    Matsumoto, H.4    Kamada, T.5    Kusunoki, H.6
  • 17
    • 84928584012 scopus 로고    scopus 로고
    • MicroRNA-92 promotes gastric cancer cell proliferation and invasion through targeting FXR
    • 1:CAS:528:DC%2BC2cXhtlarsrbO 25095974
    • Duan JH, Fang L. MicroRNA-92 promotes gastric cancer cell proliferation and invasion through targeting FXR. Tumour Biol. 2014;35:11013-9.
    • (2014) Tumour Biol , vol.35 , pp. 11013-11019
    • Duan, J.H.1    Fang, L.2
  • 18
    • 84898812837 scopus 로고    scopus 로고
    • Prognostic role of microRNA-100 in various carcinomas: Evidence from six studies
    • 1:CAS:528:DC%2BC2cXmtlWgsbk%3D 24258109
    • Chen J, Zheng B, Wang C, Chen Y, Du C, Zhao G, et al. Prognostic role of microRNA-100 in various carcinomas: evidence from six studies. Tumour Biol. 2014;35:3067-71.
    • (2014) Tumour Biol , vol.35 , pp. 3067-3071
    • Chen, J.1    Zheng, B.2    Wang, C.3    Chen, Y.4    Du, C.5    Zhao, G.6
  • 19
    • 84896707001 scopus 로고    scopus 로고
    • Upregulation of microRNA-107 induces proliferation in human gastric cancer cells by targeting the transcription factor FOXO1
    • 1:CAS:528:DC%2BC2cXhtFSnurw%3D 24374340
    • Li F, Liu B, Gao Y, Liu Y, Xu Y, Tong W, et al. Upregulation of microRNA-107 induces proliferation in human gastric cancer cells by targeting the transcription factor FOXO1. FEBS Lett. 2014;588:538-44.
    • (2014) FEBS Lett , vol.588 , pp. 538-544
    • Li, F.1    Liu, B.2    Gao, Y.3    Liu, Y.4    Xu, Y.5    Tong, W.6
  • 20
    • 77955619456 scopus 로고    scopus 로고
    • MiR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
    • 1:CAS:528:DC%2BC3cXhsVGhtrfI 20162574
    • Zhu W, Shan X, Wang T, Shu Y, Liu P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int J Cancer. 2010;127:2520-9.
    • (2010) Int J Cancer , vol.127 , pp. 2520-2529
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 21
    • 84884708989 scopus 로고    scopus 로고
    • Prognostic role of microRNA polymorphisms in advanced gastric cancer: A translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)
    • 1:STN:280:DC%2BC3sbktVCltg%3D%3D 23975664
    • Stenholm L, Stoehlmacher-Williams J, Al-Batran SE, Heussen N, Akin S, Pauligk C, et al. Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). Ann Oncol. 2013;24:2581-8.
    • (2013) Ann Oncol , vol.24 , pp. 2581-2588
    • Stenholm, L.1    Stoehlmacher-Williams, J.2    Al-Batran, S.E.3    Heussen, N.4    Akin, S.5    Pauligk, C.6
  • 22
    • 84899082767 scopus 로고    scopus 로고
    • Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho
    • 3994330 24655788
    • He XJ, Ma YY, Yu S, Jiang XT, Lu YD, Tao L, et al. Up-regulated miR-199a-5p in gastric cancer functions as an oncogene and targets klotho. BMC Cancer. 2014;14:218.
    • (2014) BMC Cancer , vol.14 , pp. 218
    • He, X.J.1    Ma, Y.Y.2    Yu, S.3    Jiang, X.T.4    Lu, Y.D.5    Tao, L.6
  • 23
    • 84898786570 scopus 로고    scopus 로고
    • Optimal chemotherapy for advanced gastric cancer: Is there a global consensus?
    • 1:CAS:528:DC%2BC2cXls12ju74%3D 24048758
    • Lordick F, Lorenzen S, Yamada Y, Ilson D. Optimal chemotherapy for advanced gastric cancer: is there a global consensus? Gastric Cancer. 2014;17:213-25.
    • (2014) Gastric Cancer , vol.17 , pp. 213-225
    • Lordick, F.1    Lorenzen, S.2    Yamada, Y.3    Ilson, D.4
  • 24
    • 77949808915 scopus 로고    scopus 로고
    • The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin
    • 1:CAS:528:DC%2BC3cXjsFegurw%3D 20163198
    • Brozovic A, Ambriović-Ristov A, Osmak M. The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin. Crit Rev Toxicol. 2010;40:347-59.
    • (2010) Crit Rev Toxicol , vol.40 , pp. 347-359
    • Brozovic, A.1    Ambriović-Ristov, A.2    Osmak, M.3
  • 25
    • 84862813484 scopus 로고    scopus 로고
    • MicroRNA-223 regulates FOXO1 expression and cell proliferation
    • 1:CAS:528:DC%2BC38XktFGisLk%3D 22569260
    • Wu L, Li H, Jia CY, Cheng W, Yu M, Peng M, et al. MicroRNA-223 regulates FOXO1 expression and cell proliferation. FEBS Lett. 2012;586:1038-43.
    • (2012) FEBS Lett , vol.586 , pp. 1038-1043
    • Wu, L.1    Li, H.2    Jia, C.Y.3    Cheng, W.4    Yu, M.5    Peng, M.6
  • 26
    • 84879486215 scopus 로고    scopus 로고
    • MiR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2
    • 24137330
    • Nian W, Ao X, Wu Y, Huang Y, Shao J, Wang Y, et al. miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2. Oncol Lett. 2013;6:359-66.
    • (2013) Oncol Lett , vol.6 , pp. 359-366
    • Nian, W.1    Ao, X.2    Wu, Y.3    Huang, Y.4    Shao, J.5    Wang, Y.6
  • 27
    • 84864492302 scopus 로고    scopus 로고
    • Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection
    • 3408505 1:CAS:528:DC%2BC38XhtFCnsbrL 22860003
    • Li BS, Zhao YL, Guo G, Li W, Zhu ED, Luo X, et al. Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection. PLoS One. 2012;7:e41629.
    • (2012) PLoS One , vol.7 , pp. 41629
    • Li, B.S.1    Zhao, Y.L.2    Guo, G.3    Li, W.4    Zhu, E.D.5    Luo, X.6
  • 28
    • 79960670757 scopus 로고    scopus 로고
    • MiRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3
    • 1:CAS:528:DC%2BC3MXptVOktrc%3D 21628394
    • Li X, Zhang Y, Zhang H, Liu X, Gong T, Li M, et al. miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3. Mol Cancer Res. 2011;9:824-33.
    • (2011) Mol Cancer Res , vol.9 , pp. 824-833
    • Li, X.1    Zhang, Y.2    Zhang, H.3    Liu, X.4    Gong, T.5    Li, M.6
  • 29
    • 84961288227 scopus 로고    scopus 로고
    • F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner
    • doi:10.1172/JCI78782
    • Yumimoto K, Akiyoshi S, Ueo H, Sagara Y, Onoyama I, Ueo H, et al.: F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner. J Clin Invest 2015, doi:10.1172/JCI78782.
    • (2015) J Clin Invest
    • Yumimoto, K.1    Akiyoshi, S.2    Ueo, H.3    Sagara, Y.4    Onoyama, I.5    Ueo, H.6
  • 30
    • 65949107856 scopus 로고    scopus 로고
    • P53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases
    • 1:CAS:528:DC%2BD1MXltFOks7o%3D 19366810
    • Yokobori T, Mimori K, Iwatsuki M, Ishii H, Onoyama I, Fukagawa T, et al. p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases. Cancer Res. 2009;69:3788-94.
    • (2009) Cancer Res , vol.69 , pp. 3788-3794
    • Yokobori, T.1    Mimori, K.2    Iwatsuki, M.3    Ishii, H.4    Onoyama, I.5    Fukagawa, T.6
  • 31
    • 84902511908 scopus 로고    scopus 로고
    • Fbw7-dependent cyclin e regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism
    • 3939062 1:CAS:528:DC%2BC3sXhtFCjurbP 23873023
    • Xu Y, Swartz KL, Siu KT, Bhattacharyya M, Minella AC. Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism. Oncogene. 2014;33:3161-71.
    • (2014) Oncogene , vol.33 , pp. 3161-3171
    • Xu, Y.1    Swartz, K.L.2    Siu, K.T.3    Bhattacharyya, M.4    Minella, A.C.5
  • 32
    • 38549086019 scopus 로고    scopus 로고
    • FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
    • 1:CAS:528:DC%2BD1cXhtVGhs7Y%3D 18094723
    • Welcker M, Clurman BE. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer. 2008;8:83-93.
    • (2008) Nat Rev Cancer , vol.8 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 33
    • 10644269326 scopus 로고    scopus 로고
    • Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene
    • 1:CAS:528:DC%2BD2cXhtVGmtb7L 15592418
    • Mao JH, Perez-Losada J, Wu D, Delrosario R, Tsunematsu R, Nakayama KI, et al. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature. 2004;432:775-9.
    • (2004) Nature , vol.432 , pp. 775-779
    • Mao, J.H.1    Perez-Losada, J.2    Wu, D.3    Delrosario, R.4    Tsunematsu, R.5    Nakayama, K.I.6
  • 34
    • 84910628229 scopus 로고    scopus 로고
    • Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma
    • 1:CAS:528:DC%2BC2cXhvFSqu7jE 25269767
    • Li L, Sarver AL, Khatri R, Hajeri PB, Kamenev I, French AJ, et al. Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma. J Pathol. 2014;234:488-501.
    • (2014) J Pathol , vol.234 , pp. 488-501
    • Li, L.1    Sarver, A.L.2    Khatri, R.3    Hajeri, P.B.4    Kamenev, I.5    French, A.J.6
  • 35
    • 84926471462 scopus 로고    scopus 로고
    • P53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma
    • 1:CAS:528:DC%2BC2MXks1yju7s%3D 25512615
    • Li Z, Sun Y, Chen X, Squires J, Nowroozizadeh B, Liang C, et al. p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma. Mol Cancer Res. 2015;13:584-91.
    • (2015) Mol Cancer Res. , vol.13 , pp. 584-591
    • Li, Z.1    Sun, Y.2    Chen, X.3    Squires, J.4    Nowroozizadeh, B.5    Liang, C.6
  • 36
    • 84925282873 scopus 로고    scopus 로고
    • Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC2cXotFeksb4%3D 24727676
    • Kumar V, Palermo R, Talora C, Campese AF, Checquolo S, Bellavia D, et al. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:2324-35.
    • (2014) Leukemia , vol.28 , pp. 2324-2335
    • Kumar, V.1    Palermo, R.2    Talora, C.3    Campese, A.F.4    Checquolo, S.5    Bellavia, D.6
  • 37
    • 79959923295 scopus 로고    scopus 로고
    • MiRNA-27a controls FBW7/hCDC4-dependent cyclin e degradation and cell cycle progression
    • 1:CAS:528:DC%2BC38Xktlemug%3D%3D 21597324
    • Lerner M, Lundgren J, Akhoondi S, Jahn A, Ng HF, Akbari Moqadam F, et al. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression. Cell Cycle. 2011;10:2172-83.
    • (2011) Cell Cycle , vol.10 , pp. 2172-2183
    • Lerner, M.1    Lundgren, J.2    Akhoondi, S.3    Jahn, A.4    Ng, H.F.5    Akbari Moqadam, F.6
  • 38
    • 84887881695 scopus 로고    scopus 로고
    • The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis
    • 3924345 24261825
    • Ren H, Koo J, Guan B, Yue P, Deng X, et al. The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis. Mol Cancer. 2013;12:146.
    • (2013) Mol Cancer , vol.12 , pp. 146
    • Ren, H.1    Koo, J.2    Guan, B.3    Yue, P.4    Deng, X.5


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