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Volumn 11, Issue 3, 2015, Pages 1-20

HCV Induces the Expression of Rubicon and UVRAG to Temporally Regulate the Maturation of Autophagosomes and Viral Replication

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; RUBICON PROTEIN; UNCLASSIFIED DRUG; UVRAG PROTEIN; RUNDATAXIN PROTEIN, HUMAN; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN; UVRAG PROTEIN, HUMAN;

EID: 84926451754     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004764     Document Type: Article
Times cited : (103)

References (45)
  • 2
    • 0345188811 scopus 로고    scopus 로고
    • Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
    • Lohmann V, Korner F, Koch J, Herian U, Theilmann L, et al. (1999) Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285: 110–113. 10390360
    • (1999) Science , vol.285 , pp. 110-113
    • Lohmann, V.1    Korner, F.2    Koch, J.3    Herian, U.4    Theilmann, L.5
  • 3
    • 39749116856 scopus 로고    scopus 로고
    • Hepatitis C virus genotype 1a growth and induction of autophagy
    • Ait-Goughoulte M, Kanda T, Meyer K, Ryerse JS, Ray RB, et al. (2008) Hepatitis C virus genotype 1a growth and induction of autophagy. J Virol 82: 2241–2249. 18077704
    • (2008) J Virol , vol.82 , pp. 2241-2249
    • Ait-Goughoulte, M.1    Kanda, T.2    Meyer, K.3    Ryerse, J.S.4    Ray, R.B.5
  • 4
    • 69549135689 scopus 로고    scopus 로고
    • The autophagy machinery is required to initiate hepatitis C virus replication
    • Dreux M, Gastaminza P, Wieland SF, Chisari FV, (2009) The autophagy machinery is required to initiate hepatitis C virus replication. Proc Natl Acad Sci U S A 106: 14046–14051. doi: 10.1073/pnas.0907344106 19666601
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14046-14051
    • Dreux, M.1    Gastaminza, P.2    Wieland, S.F.3    Chisari, F.V.4
  • 5
    • 54449101892 scopus 로고    scopus 로고
    • Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response
    • Sir D, Chen WL, Choi J, Wakita T, Yen TS, et al. (2008) Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response. Hepatology 48: 1054–1061. doi: 10.1002/hep.22464 18688877
    • (2008) Hepatology , vol.48 , pp. 1054-1061
    • Sir, D.1    Chen, W.L.2    Choi, J.3    Wakita, T.4    Yen, T.S.5
  • 6
    • 84868125839 scopus 로고    scopus 로고
    • Hepatitis C virus-induced autophagy is independent of the unfolded protein response
    • Mohl BP, Tedbury PR, Griffin S, Harris M, (2012) Hepatitis C virus-induced autophagy is independent of the unfolded protein response. J Virol 86: 10724–10732. doi: 10.1128/JVI.01667-12 22837205
    • (2012) J Virol , vol.86 , pp. 10724-10732
    • Mohl, B.P.1    Tedbury, P.R.2    Griffin, S.3    Harris, M.4
  • 7
    • 78650961487 scopus 로고    scopus 로고
    • Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro
    • Ke PY, Chen SS, (2011) Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. J Clin Invest 121: 37–56. doi: 10.1172/JCI41474 21135505
    • (2011) J Clin Invest , vol.121 , pp. 37-56
    • Ke, P.Y.1    Chen, S.S.2
  • 8
    • 80054978956 scopus 로고    scopus 로고
    • Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy
    • Su WC, Chao TC, Huang YL, Weng SC, Jeng KS, et al. (2011) Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. J Virol 85: 10561–10571. doi: 10.1128/JVI.00173-11 21835792
    • (2011) J Virol , vol.85 , pp. 10561-10571
    • Su, W.C.1    Chao, T.C.2    Huang, Y.L.3    Weng, S.C.4    Jeng, K.S.5
  • 9
    • 84855827121 scopus 로고    scopus 로고
    • Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus
    • Taguwa S, Kambara H, Fujita N, Noda T, Yoshimori T, et al. (2011) Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. J Virol 85: 13185–13194. doi: 10.1128/JVI.06099-11 21994453
    • (2011) J Virol , vol.85 , pp. 13185-13194
    • Taguwa, S.1    Kambara, H.2    Fujita, N.3    Noda, T.4    Yoshimori, T.5
  • 10
    • 84865103087 scopus 로고    scopus 로고
    • Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling
    • Shrivastava S, Bhanja Chowdhury J, Steele R, Ray R, Ray RB, (2012) Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling. J Virol 86: 8705–8712. doi: 10.1128/JVI.00616-12 22674982
    • (2012) J Virol , vol.86 , pp. 8705-8712
    • Shrivastava, S.1    Bhanja, C.J.2    Steele, R.3    Ray, R.4    Ray, R.B.5
  • 11
    • 84873669841 scopus 로고    scopus 로고
    • Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy
    • Huang H, Kang R, Wang J, Luo G, Yang W, et al. (2013) Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy 9: 175–195. doi: 10.4161/auto.22791 23169238
    • (2013) Autophagy , vol.9 , pp. 175-195
    • Huang, H.1    Kang, R.2    Wang, J.3    Luo, G.4    Yang, W.5
  • 12
    • 84861556595 scopus 로고    scopus 로고
    • Replication of hepatitis C virus RNA on autophagosomal membranes
    • Sir D, Kuo CF, Tian Y, Liu HM, Huang EJ, et al. (2012) Replication of hepatitis C virus RNA on autophagosomal membranes. J Biol Chem 287: 18036–18043. doi: 10.1074/jbc.M111.320085 22496373
    • (2012) J Biol Chem , vol.287 , pp. 18036-18043
    • Sir, D.1    Kuo, C.F.2    Tian, Y.3    Liu, H.M.4    Huang, E.J.5
  • 13
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G, (2008) Autophagy in the pathogenesis of disease. Cell 132: 27–42. doi: 10.1016/j.cell.2007.12.018 18191218
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 14
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • Simonsen A, Tooze SA, (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 186: 773–782. doi: 10.1083/jcb.200907014 19797076
    • (2009) J Cell Biol , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 15
    • 67650305520 scopus 로고    scopus 로고
    • Regulation of Beclin 1 in autophagy
    • Sun Q, Fan W, Zhong Q, (2009) Regulation of Beclin 1 in autophagy. Autophagy 5: 713–716. 19372752
    • (2009) Autophagy , vol.5 , pp. 713-716
    • Sun, Q.1    Fan, W.2    Zhong, Q.3
  • 16
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura E, Kishi C, Inoue K, Mizushima N, (2008) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell 19: 5360–5372. doi: 10.1091/mbc.E08-01-0080 18843052
    • (2008) Mol Biol Cell , vol.19 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 17
    • 58049192897 scopus 로고    scopus 로고
    • Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
    • Sun Q, Fan W, Chen K, Ding X, Chen S, et al. (2008) Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A 105: 19211–19216. doi: 10.1073/pnas.0810452105 19050071
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19211-19216
    • Sun, Q.1    Fan, W.2    Chen, K.3    Ding, X.4    Chen, S.5
  • 18
    • 33745751085 scopus 로고    scopus 로고
    • Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
    • Liang C, Feng P, Ku B, Dotan I, Canaani D, et al. (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8: 688–699. 16799551
    • (2006) Nat Cell Biol , vol.8 , pp. 688-699
    • Liang, C.1    Feng, P.2    Ku, B.3    Dotan, I.4    Canaani, D.5
  • 19
    • 84884819157 scopus 로고    scopus 로고
    • Autophagosome formation—the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage
    • Wirth M, Joachim J, Tooze SA, (2013) Autophagosome formation—the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage. Semin Cancer Biol 23: 301–309. doi: 10.1016/j.semcancer.2013.05.007 23727157
    • (2013) Semin Cancer Biol , vol.23 , pp. 301-309
    • Wirth, M.1    Joachim, J.2    Tooze, S.A.3
  • 20
    • 46449120732 scopus 로고    scopus 로고
    • Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
    • Liang C, Lee JS, Inn KS, Gack MU, Li Q, et al. (2008) Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nat Cell Biol 10: 776–787. doi: 10.1038/ncb1740 18552835
    • (2008) Nat Cell Biol , vol.10 , pp. 776-787
    • Liang, C.1    Lee, J.S.2    Inn, K.S.3    Gack, M.U.4    Li, Q.5
  • 21
    • 64049086758 scopus 로고    scopus 로고
    • Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
    • Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, et al. (2009) Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol 11: 385–396. doi: 10.1038/ncb1846 19270696
    • (2009) Nat Cell Biol , vol.11 , pp. 385-396
    • Matsunaga, K.1    Saitoh, T.2    Tabata, K.3    Omori, H.4    Satoh, T.5
  • 22
    • 78650600158 scopus 로고    scopus 로고
    • Rubicon controls endosome maturation as a Rab7 effector
    • Sun Q, Westphal W, Wong KN, Tan I, Zhong Q, (2010) Rubicon controls endosome maturation as a Rab7 effector. Proc Natl Acad Sci U S A 107: 19338–19343. doi: 10.1073/pnas.1010554107 20974968
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19338-19343
    • Sun, Q.1    Westphal, W.2    Wong, K.N.3    Tan, I.4    Zhong, Q.5
  • 23
    • 50249087889 scopus 로고    scopus 로고
    • Perturbation of autophagic pathway by hepatitis C virus
    • Sir D, Liang C, Chen WL, Jung JU, Ou JH, (2008) Perturbation of autophagic pathway by hepatitis C virus. Autophagy 4: 830–831. 18635950
    • (2008) Autophagy , vol.4 , pp. 830-831
    • Sir, D.1    Liang, C.2    Chen, W.L.3    Jung, J.U.4    Ou, J.H.5
  • 24
    • 84899634895 scopus 로고    scopus 로고
    • Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence
    • Kim SJ, Syed GH, Khan M, Chiu WW, Sohail MA, et al. (2014) Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence. Proc Natl Acad Sci U S A 111: 6413–6418. doi: 10.1073/pnas.1321114111 24733894
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 6413-6418
    • Kim, S.J.1    Syed, G.H.2    Khan, M.3    Chiu, W.W.4    Sohail, M.A.5
  • 25
    • 84875993938 scopus 로고    scopus 로고
    • Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy
    • Kim SJ, Syed GH, Siddiqui A, (2013) Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog 9: e1003285. doi: 10.1371/journal.ppat.1003285 23555273
    • (2013) PLoS Pathog , vol.9
    • Kim, S.J.1    Syed, G.H.2    Siddiqui, A.3
  • 26
    • 84871280686 scopus 로고    scopus 로고
    • Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry
    • Liu Z, Tian Y, Machida K, Lai MM, Luo G, et al. (2012) Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry. J Biol Chem 287: 41922–41930. doi: 10.1074/jbc.M112.414789 23095753
    • (2012) J Biol Chem , vol.287 , pp. 41922-41930
    • Liu, Z.1    Tian, Y.2    Machida, K.3    Lai, M.M.4    Luo, G.5
  • 27
    • 84866156581 scopus 로고    scopus 로고
    • Cell culture-adaptive mutations promote viral protein-protein interactions and morphogenesis of infectious hepatitis C virus
    • Jiang J, Luo G, (2012) Cell culture-adaptive mutations promote viral protein-protein interactions and morphogenesis of infectious hepatitis C virus. J Virol 86: 8987–8997. doi: 10.1128/JVI.00004-12 22674987
    • (2012) J Virol , vol.86 , pp. 8987-8997
    • Jiang, J.1    Luo, G.2
  • 29
    • 84904631176 scopus 로고    scopus 로고
    • Membranous replication factories induced by plus-strand RNA viruses
    • Romero-Brey I, Bartenschlager R, (2014) Membranous replication factories induced by plus-strand RNA viruses. Viruses 6: 2826–2857. doi: 10.3390/v6072826 25054883
    • (2014) Viruses , vol.6 , pp. 2826-2857
    • Romero-Brey, I.1    Bartenschlager, R.2
  • 30
    • 84885995316 scopus 로고    scopus 로고
    • Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
    • Paul D, Hoppe S, Saher G, Krijnse-Locker J, Bartenschlager R, (2013) Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment. J Virol 87: 10612–10627. doi: 10.1128/JVI.01370-13 23885072
    • (2013) J Virol , vol.87 , pp. 10612-10627
    • Paul, D.1    Hoppe, S.2    Saher, G.3    Krijnse-Locker, J.4    Bartenschlager, R.5
  • 31
    • 34247559591 scopus 로고    scopus 로고
    • Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery
    • Stone M, Jia S, Heo WD, Meyer T, Konan KV, (2007) Participation of rab5, an early endosome protein, in hepatitis C virus RNA replication machinery. J Virol 81: 4551–4563. 17301141
    • (2007) J Virol , vol.81 , pp. 4551-4563
    • Stone, M.1    Jia, S.2    Heo, W.D.3    Meyer, T.4    Konan, K.V.5
  • 32
    • 68549086862 scopus 로고    scopus 로고
    • Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activation
    • Li S, Ye L, Yu X, Xu B, Li K, et al. (2009) Hepatitis C virus NS4B induces unfolded protein response and endoplasmic reticulum overload response-dependent NF-kappaB activation. Virology 391: 257–264. doi: 10.1016/j.virol.2009.06.039 19628242
    • (2009) Virology , vol.391 , pp. 257-264
    • Li, S.1    Ye, L.2    Yu, X.3    Xu, B.4    Li, K.5
  • 33
    • 84901034931 scopus 로고    scopus 로고
    • Phosphoprotein of human parainfluenza virus type 3 blocks autophagosome-lysosome fusion to increase virus production
    • Ding B, Zhang G, Yang X, Zhang S, Chen L, et al. (2014) Phosphoprotein of human parainfluenza virus type 3 blocks autophagosome-lysosome fusion to increase virus production. Cell Host Microbe 15: 564–577. doi: 10.1016/j.chom.2014.04.004 24832451
    • (2014) Cell Host Microbe , vol.15 , pp. 564-577
    • Ding, B.1    Zhang, G.2    Yang, X.3    Zhang, S.4    Chen, L.5
  • 34
    • 84861307200 scopus 로고    scopus 로고
    • Accumulation of autophagosomes in Semliki Forest virus-infected cells is dependent on expression of the viral glycoproteins
    • Eng KE, Panas MD, Murphy D, Karlsson Hedestam GB, McInerney GM, (2012) Accumulation of autophagosomes in Semliki Forest virus-infected cells is dependent on expression of the viral glycoproteins. J Virol 86: 5674–5685. doi: 10.1128/JVI.06581-11 22438538
    • (2012) J Virol , vol.86 , pp. 5674-5685
    • Eng, K.E.1    Panas, M.D.2    Murphy, D.3    Karlsson, H.G.B.4    McInerney, G.M.5
  • 35
    • 73849087396 scopus 로고    scopus 로고
    • Autophagy in viral replication and pathogenesis
    • Sir D, Ou JH, (2010) Autophagy in viral replication and pathogenesis. Mol Cells 29: 1–7. doi: 10.1007/s10059-010-0014-2 20077024
    • (2010) Mol Cells , vol.29 , pp. 1-7
    • Sir, D.1    Ou, J.H.2
  • 36
    • 84874420024 scopus 로고    scopus 로고
    • Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-beta signaling is required for rotavirus replication
    • Crawford SE, Hyser JM, Utama B, Estes MK, (2012) Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-beta signaling is required for rotavirus replication. Proc Natl Acad Sci U S A 109: E3405–3413. doi: 10.1073/pnas.1216539109 23184977
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 3405-3413
    • Crawford, S.E.1    Hyser, J.M.2    Utama, B.3    Estes, M.K.4
  • 37
    • 41449113692 scopus 로고    scopus 로고
    • Potential subversion of autophagosomal pathway by picornaviruses
    • Taylor MP, Kirkegaard K, (2008) Potential subversion of autophagosomal pathway by picornaviruses. Autophagy 4: 286–289. 18094610
    • (2008) Autophagy , vol.4 , pp. 286-289
    • Taylor, M.P.1    Kirkegaard, K.2
  • 38
    • 36049014444 scopus 로고    scopus 로고
    • Modification of cellular autophagy protein LC3 by poliovirus
    • Taylor MP, Kirkegaard K, (2007) Modification of cellular autophagy protein LC3 by poliovirus. J Virol 81: 12543–12553. 17804493
    • (2007) J Virol , vol.81 , pp. 12543-12553
    • Taylor, M.P.1    Kirkegaard, K.2
  • 39
    • 50949133741 scopus 로고    scopus 로고
    • Autophagosome supports coxsackievirus B3 replication in host cells
    • Wong J, Zhang J, Si X, Gao G, Mao I, et al. (2008) Autophagosome supports coxsackievirus B3 replication in host cells. J Virol 82: 9143–9153. doi: 10.1128/JVI.00641-08 18596087
    • (2008) J Virol , vol.82 , pp. 9143-9153
    • Wong, J.1    Zhang, J.2    Si, X.3    Gao, G.4    Mao, I.5
  • 40
    • 84908086989 scopus 로고    scopus 로고
    • Poliovirus-induced changes in cellular membranes throughout infection
    • Jackson WT, (2014) Poliovirus-induced changes in cellular membranes throughout infection. Curr Opin Virol 9: 67–73. doi: 10.1016/j.coviro.2014.09.007 25310497
    • (2014) Curr Opin Virol , vol.9 , pp. 67-73
    • Jackson, W.T.1
  • 41
    • 62749134544 scopus 로고    scopus 로고
    • Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes
    • Panyasrivanit M, Khakpoor A, Wikan N, Smith DR, (2009) Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes. J Gen Virol 90: 448–456. doi: 10.1099/vir.0.005355-0 19141455
    • (2009) J Gen Virol , vol.90 , pp. 448-456
    • Panyasrivanit, M.1    Khakpoor, A.2    Wikan, N.3    Smith, D.R.4
  • 42
    • 67449086380 scopus 로고    scopus 로고
    • A role for autophagolysosomes in dengue virus 3 production in HepG2 cells
    • Khakpoor A, Panyasrivanit M, Wikan N, Smith DR, (2009) A role for autophagolysosomes in dengue virus 3 production in HepG2 cells. J Gen Virol 90: 1093–1103. doi: 10.1099/vir.0.007914-0 19264601
    • (2009) J Gen Virol , vol.90 , pp. 1093-1103
    • Khakpoor, A.1    Panyasrivanit, M.2    Wikan, N.3    Smith, D.R.4
  • 43
    • 84886303412 scopus 로고    scopus 로고
    • Kaposi's Sarcoma-Associated Herpesvirus K7 Modulates Rubicon-Mediated Inhibition of Autophagosome Maturation
    • Liang Q, Chang B, Brulois KF, Castro K, Min CK, et al. (2013) Kaposi's Sarcoma-Associated Herpesvirus K7 Modulates Rubicon-Mediated Inhibition of Autophagosome Maturation. J Virol 87: 12499–12503. doi: 10.1128/JVI.01898-13 24027317
    • (2013) J Virol , vol.87 , pp. 12499-12503
    • Liang, Q.1    Chang, B.2    Brulois, K.F.3    Castro, K.4    Min, C.K.5
  • 44
    • 79961201856 scopus 로고    scopus 로고
    • Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome
    • Wang L, Jeng KS, Lai MM, (2011) Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome. J Virol 85: 7954–7964. doi: 10.1128/JVI.00339-11 21632751
    • (2011) J Virol , vol.85 , pp. 7954-7964
    • Wang, L.1    Jeng, K.S.2    Lai, M.M.3
  • 45
    • 0028840840 scopus 로고
    • Differential subcellular localization of hepatitis C virus core gene products
    • Lo SY, Masiarz F, Hwang SB, Lai MM, Ou JH, (1995) Differential subcellular localization of hepatitis C virus core gene products. Virology 213: 455–461. 7491770
    • (1995) Virology , vol.213 , pp. 455-461
    • Lo, S.Y.1    Masiarz, F.2    Hwang, S.B.3    Lai, M.M.4    Ou, J.H.5


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