Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 17, 2014, Pages 6413-6418

  Kim, Seong Jun ^a   Syed, Gulam H ^a   Khan, Mohsin ^a   Chiu, Wei Wei ^a   Sohail, Muhammad A ^a   Gish, Robert G ^b   Siddiqui, Aleem ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b HEPATITIS B FOUNDATION   (United States)

Author keywords

Autophagy; HCV persistence; Innate immunity

Indexed keywords

CASPASE 3; CYTOCHROME C; DYNAMIN I; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); RED FLUORESCENT PROTEIN;

APOPTOSIS; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; GLYCOLYSIS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INNATE IMMUNITY; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MITOPHAGY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION;

AUTOPHAGY; HCV PERSISTENCE; INNATE IMMUNITY;

APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; DYNAMINS; HEPACIVIRUS; HUMANS; IMMUNE EVASION; IMMUNITY, INNATE; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN TRANSPORT;

EID: 84899634895     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321114111     Document Type: Article

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