Toward Ideality: The Synthesis of (+)-Kalkitoxin and (+)-Hydroxyphthioceranic Acid by Assembly-Line Synthesis

Journal of the American Chemical Society

Volumn 137, Issue 13, 2015, Pages 4398-4403

  Balieu, Sebastien ^a   Hallett, Gayle E ^a   Burns, Matthew ^a   Bootwicha, Teerawut ^a   Studley, John ^b   Aggarwal, Varinder K ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTERIFICATION; ESTERS; MOLECULES; PURIFICATION; REACTION INTERMEDIATES; STEREOCHEMISTRY;

ASSEMBLY LINE; AVAILABLE P; BORONIC ESTERS; CHEMICAL EQUATIONS; COMPLEX MOLECULES; EFFICIENT SYNTHESIS; NATURAL PRODUCTS;

SYNTHESIS (CHEMICAL);

BENZOIC ACID; BORON DERIVATIVE; ESTER; HYDROXYPHTHIOCERANIC ACID; KALKITOXIN; LIPOPEPTIDE; NATURAL PRODUCT; NEUROTOXIN; SPARTEINE; UNCLASSIFIED DRUG; BORONIC ACID DERIVATIVE; FATTY ACID; LIPID; PHTHIOCERANIC ACID; THIAZOLE DERIVATIVE;

ARTICLE; ASSEMBLY LINE SYNTHESIS; CHEMICAL BOND; CHEMICAL MODIFICATION; CRYSTALLIZATION; DIASTEREOISOMER; NERVE CELL CULTURE; NERVE FUNCTION; OXIDATION; SYNTHESIS; TOXIN SYNTHESIS; CHEMISTRY; STEREOISOMERISM;

BORONIC ACIDS; CHEMISTRY TECHNIQUES, SYNTHETIC; FATTY ACIDS; LIPIDS; STEREOISOMERISM; THIAZOLES;

EID: 84926433821     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja512875g     Document Type: Article

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