Curtailing endothelial TGF-β signaling is sufficient to reduce endothelial-mesenchymal transition and fibrosis in CKD

Journal of the American Society of Nephrology

Volumn 26, Issue 4, 2015, Pages 817-829

  Xavier, Sandhya ^a   Vasko, Radovan ^a,b   Matsumoto, Kei ^a   Zullo, Joseph A ^a   Chen, Robert ^a   Maizel, Julien ^a   Chander, Praveen N ^a   Goligorsky, Michael S ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; ENDOGLIN; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; ENDOGLIN PROTEIN, MOUSE; FOLIC ACID; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HYPOXEMIA; KIDNEY BLOOD FLOW; KIDNEY FIBROSIS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL TRANSDIFFERENTIATION; CHRONIC KIDNEY FAILURE; ENDOTHELIUM; FIBROSIS; GENETICS; KIDNEY; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE; URETER OBSTRUCTION;

ANIMALS; CELL TRANSDIFFERENTIATION; ENDOTHELIUM; FIBROSIS; FOLIC ACID; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RENAL INSUFFICIENCY, CHRONIC; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; URETERAL OBSTRUCTION;

EID: 84926432474     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013101137     Document Type: Article

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