Dysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling

Journal of Hepatology

Volumn 62, Issue 4, 2015, Pages 889-896

  Xiao, Yongtao ^a,b,c   Wang, Jun ^a,c   Yan, Weihui ^a,c   Zhou, Ying ^a,c   Chen, Yingwei ^b,c   Zhou, Kejun ^b,c   Wen, Jie ^b,c   Wang, Yang ^b,c   Cai, Wei ^a,b,c  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Institute of Pediatric Research   (China)

^c Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition   (China)

Author keywords

Cholangiocytes; Cholestasis; IL 6; MicroRNA; Proliferation; STAT3

Indexed keywords

BILE ACID; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; MICRORNA; MICRORNA 124; MICRORNA 200; STAT3 PROTEIN; FOXA2 PROTEIN, HUMAN; MIRN124 MICRORNA, HUMAN; MIRN124 MICRORNA, RAT; MIRN200 MICRORNA, HUMAN; MIRN200 MICRORNA, RAT;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT ATRESIA; BILE DUCT LIGATION; BIOLOGICAL FUNCTIONS; CELL HYPERPLASIA; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CELLS BY BODY ANATOMY; CHOLANGIOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRAHEPATIC CHOLESTASIS; LUCIFERASE ASSAY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BILE DUCT; CHOLESTASIS; COMPLICATION; FEMALE; GENETICS; INFANT; LIVER; METABOLISM; PATHOLOGY; PRESCHOOL CHILD; SPRAGUE DAWLEY RAT; STATISTICS;

ANIMALS; BILE DUCTS; BILIARY ATRESIA; CELL PROLIFERATION; CHILD, PRESCHOOL; CHOLESTASIS; FEMALE; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; INFANT; INTERLEUKIN-6; LIVER; MALE; MICRORNAS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STATISTICS AS TOPIC;

EID: 84926416151     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.10.033     Document Type: Article

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