Activation of the Nrf2 defense pathway contributes to neuroprotective effects of phloretin on oxidative stress injury after cerebral ischemia/reperfusion in rats

Journal of the Neurological Sciences

Volumn 351, Issue 1-2, 2015, Pages 88-92

  Liu, Yu ^a,b   Zhang, Lei ^a   Liang, Jiangjiu ^a  

^a SHANDONG UNIVERSITY   (China)

^b WEIFANG MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia reperfusion; GSH Px; MDA; Nrf2; Phloretin; SOD

Indexed keywords

GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MESSENGER RNA; PHLORETIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN WATER; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; GENE EXPRESSION; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; MALE; METABOLIC NETWORKS AND PATHWAYS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHLORETIN; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; UP-REGULATION;

EID: 84926408618     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2015.02.045     Document Type: Article

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