Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis

Journal of Hepatology

Volumn 62, Issue 4, 2015, Pages 879-888

  Rachidi, Saleh ^a,b   Sun, Shaoli ^a   Wu, Bill X ^a,b   Jones, Elizabeth ^a   Drake, Richard R ^a   Ogretmen, Besim ^a   Cowart, L Ashley ^a,c   Clarke, Christopher J ^d   Hannun, Yusuf A ^d   Chiosis, Gabriela ^e   Liu, Bei ^a,b   Li, Zihai ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d STONY BROOK UNIVERSITY   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

gp96; Liver cancer; Molecular chaperone

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE CERAMIDASE; BILIRUBIN; CARCINOGEN; CERAMIDE; CERAMIDE SYNTHASE 1; CRE RECOMBINASE; DIETHYLNITROSAMINE; GLYCOPROTEIN GP 96; SCATTER FACTOR; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE 5; UNCLASSIFIED DRUG; ALKYLATING AGENT; CHAPERONE; GLUCOSE REGULATED PROTEIN 94; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL DEATH; CELL EXPANSION; CELL GROWTH; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FAT CONTENT; FATTY LIVER; FEMALE; GENE EXPRESSION; HEPG2 CELL LINE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LIVER FUNCTION; LIVER REGENERATION; LIVER WEIGHT; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SPHINGOLIPID METABOLISM; TISSUE DISTRIBUTION; UPREGULATION; ANIMAL; CARCINOGENESIS; DRUG EFFECTS; ENDOPLASMIC RETICULUM; LIVER; LIVER TUMOR; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALKYLATING AGENTS; ANIMALS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DIETHYLNITROSAMINE; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HUMANS; LIVER; LIVER NEOPLASMS; MEMBRANE GLYCOPROTEINS; MICE; MODELS, ANIMAL; MOLECULAR CHAPERONES; SIGNAL TRANSDUCTION;

EID: 84926408232     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.11.010     Document Type: Article

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