-
1
-
-
33745533559
-
Liver stem cells and their implication in hepatocellular and cholangiocarcinoma
-
Roskams T. Liver stem cells and their implication in hepatocellular and cholangiocarcinoma. Oncogene 2006;25:3818-3822.
-
(2006)
Oncogene
, vol.25
, pp. 3818-3822
-
-
Roskams, T.1
-
2
-
-
78649690689
-
Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2
-
Galicia VA, He L, Dang H, Kanel G, Vendryes C, French BA, Zeng N, et al. Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2. Gastroenterology 2010;139:2170-2182.
-
(2010)
Gastroenterology
, vol.139
, pp. 2170-2182
-
-
Galicia, V.A.1
He, L.2
Dang, H.3
Kanel, G.4
Vendryes, C.5
French, B.A.6
Zeng, N.7
-
3
-
-
34447558236
-
ER chaperones in mammalian development and human diseases
-
Ni M, Lee AS. ER chaperones in mammalian development and human diseases. FEBS Lett 2007;581:3641-3651.
-
(2007)
FEBS Lett
, vol.581
, pp. 3641-3651
-
-
Ni, M.1
Lee, A.S.2
-
4
-
-
77952589171
-
GRP94 in ER quality control and stress responses
-
Eletto D, Dersh D, Argon Y. GRP94 in ER quality control and stress responses. Semin Cell Dev Biol 2010;21:479-485.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 479-485
-
-
Eletto, D.1
Dersh, D.2
Argon, Y.3
-
5
-
-
40949111869
-
Biology and pathobiology of gap junctional channels in hepatocytes
-
Vinken M, Henkens T, De Rop E, Fraczek J, Vanhaecke T, Rogiers V. Biology and pathobiology of gap junctional channels in hepatocytes. Hepatology 2008;47:1077-1088.
-
(2008)
Hepatology
, vol.47
, pp. 1077-1088
-
-
Vinken, M.1
Henkens, T.2
De Rop, E.3
Fraczek, J.4
Vanhaecke, T.5
Rogiers, V.6
-
6
-
-
2942548177
-
Tumor suppressor gene E-cadherin and its role in normal and malignant cells
-
Pecina-Slaus N. Tumor suppressor gene E-cadherin and its role in normal and malignant cells. Cancer Cell Int 2003;3:17.
-
(2003)
Cancer Cell Int
, vol.3
, pp. 17
-
-
Pecina-Slaus, N.1
-
7
-
-
84864422202
-
beta1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model
-
Moran-Jones K, Ledger A, Naylor MJ. beta1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model. Sci Rep 2012;2:526.
-
(2012)
Sci Rep
, vol.2
, pp. 526
-
-
Moran-Jones, K.1
Ledger, A.2
Naylor, M.J.3
-
8
-
-
77956296890
-
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling
-
Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, et al. Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling. PLoS One 2010;5:e10852.
-
(2010)
PLoS One
, vol.5
-
-
Mao, C.1
Wang, M.2
Luo, B.3
Wey, S.4
Dong, D.5
Wesselschmidt, R.6
-
9
-
-
84857053996
-
GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum
-
Marzec M, Eletto D, Argon Y. GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum. Biochim Biophys Acta Mol Cell Res 2012;1823:774-787.
-
(2012)
Biochim Biophys Acta Mol Cell Res
, vol.1823
, pp. 774-787
-
-
Marzec, M.1
Eletto, D.2
Argon, Y.3
-
10
-
-
79956352798
-
The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche
-
Luo B, Lam BS, Lee SH, Wey S, Zhou H, Wang M, et al. The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche. PLoS One 2011;6:e20364.
-
(2011)
PLoS One
, vol.6
-
-
Luo, B.1
Lam, B.S.2
Lee, S.H.3
Wey, S.4
Zhou, H.5
Wang, M.6
-
11
-
-
84888612260
-
Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells
-
Epub ahead of print].
-
Luo B, Tseng CC, Adams GB, Lee AS. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev 2013 [Epub ahead of print].
-
(2013)
Stem Cells Dev
-
-
Luo, B.1
Tseng, C.C.2
Adams, G.B.3
Lee, A.S.4
-
12
-
-
58049209726
-
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
-
Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, et al. Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. Proc Natl Acad Sci U S A 2008;105:19444-19449.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19444-19449
-
-
Fu, Y.1
Wey, S.2
Wang, M.3
Ye, R.4
Liao, C.P.5
Roy-Burman, P.6
-
13
-
-
33750536492
-
Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism
-
Kalra J, Shao Q, Qin H, Thomas T, Alaoui-Jamali MA, Laird DW. Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism. Carcinogenesis 2006;27:2528-2537.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2528-2537
-
-
Kalra, J.1
Shao, Q.2
Qin, H.3
Thomas, T.4
Alaoui-Jamali, M.A.5
Laird, D.W.6
-
14
-
-
0031018236
-
Dynamics of connexins, E-cadherin and alpha-catenin on cell membranes during gap junction formation
-
Fujimoto K, Nagafuchi A, Tsukita S, Kuraoka A, Ohokuma A, Shibata Y. Dynamics of connexins, E-cadherin and alpha-catenin on cell membranes during gap junction formation. J Cell Sci 1997;110(Pt 3):311-322.
-
(1997)
J Cell Sci
, vol.110
, Issue.PART 3
, pp. 311-322
-
-
Fujimoto, K.1
Nagafuchi, A.2
Tsukita, S.3
Kuraoka, A.4
Ohokuma, A.5
Shibata, Y.6
-
15
-
-
84876878450
-
Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway
-
Liu B, Staron M, Hong F, Wu BX, Sun S, Morales C, et al. Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway. Proc Natl Acad Sci U S A 2013;110:6877-6882.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6877-6882
-
-
Liu, B.1
Staron, M.2
Hong, F.3
Wu, B.X.4
Sun, S.5
Morales, C.6
-
16
-
-
84861917517
-
Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors
-
Gonzalez-Nieto D, Li L, Kohler A, Ghiaur G, Ishikawa E, Sengupta A, et al. Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood 2012;119:5144-5154.
-
(2012)
Blood
, vol.119
, pp. 5144-5154
-
-
Gonzalez-Nieto, D.1
Li, L.2
Kohler, A.3
Ghiaur, G.4
Ishikawa, E.5
Sengupta, A.6
-
17
-
-
69349099442
-
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche
-
Loulier K, Lathia JD, Marthiens V, Relucio J, Mughal MR, Tang SC, et al. beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. PLoS Biol 2009;7:e1000176.
-
(2009)
PLoS Biol
, vol.7
-
-
Loulier, K.1
Lathia, J.D.2
Marthiens, V.3
Relucio, J.4
Mughal, M.R.5
Tang, S.C.6
-
18
-
-
64849117821
-
E-Cadherin regulates neural stem cell self-renewal
-
Karpowicz P, Willaime-Morawek S, Balenci L, DeVeale B, Inoue T, van der Kooy D. E-Cadherin regulates neural stem cell self-renewal. J Neurosci 2009;29:3885-3896.
-
(2009)
J Neurosci
, vol.29
, pp. 3885-3896
-
-
Karpowicz, P.1
Willaime-Morawek, S.2
Balenci, L.3
DeVeale, B.4
Inoue, T.5
van der Kooy, D.6
-
19
-
-
4043121150
-
Immunolocalization of extracellular matrix components and integrins during mouse liver development
-
Shiojiri N, Sugiyama Y. Immunolocalization of extracellular matrix components and integrins during mouse liver development. Hepatology 2004;40:346-355.
-
(2004)
Hepatology
, vol.40
, pp. 346-355
-
-
Shiojiri, N.1
Sugiyama, Y.2
-
20
-
-
84858612400
-
Role of integrins in regulating proteases to mediate extracellular matrix remodeling
-
Yue J, Zhang K, Chen J. Role of integrins in regulating proteases to mediate extracellular matrix remodeling. Cancer Microenviron 2012;5:275-283.
-
(2012)
Cancer Microenviron
, vol.5
, pp. 275-283
-
-
Yue, J.1
Zhang, K.2
Chen, J.3
-
21
-
-
77951728697
-
Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver
-
Lorenzini S, Bird TG, Boulter L, Bellamy C, Samuel K, Aucott R, et al. Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut 2010;59:645-654.
-
(2010)
Gut
, vol.59
, pp. 645-654
-
-
Lorenzini, S.1
Bird, T.G.2
Boulter, L.3
Bellamy, C.4
Samuel, K.5
Aucott, R.6
-
22
-
-
54549093685
-
Relationships among stellate cell activation, progenitor cells, and hepatic regeneration
-
ix.
-
Roskams T. Relationships among stellate cell activation, progenitor cells, and hepatic regeneration. Clin Liver Dis 2008;12:853-860, ix.
-
(2008)
Clin Liver Dis
, vol.12
, pp. 853-860
-
-
Roskams, T.1
-
23
-
-
80053278784
-
Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury
-
Van Hul N, Lanthier N, Espanol Suner R, Abarca Quinones J, van Rooijen N, Leclercq I. Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury. Am J Pathol 2011;179:1839-1850.
-
(2011)
Am J Pathol
, vol.179
, pp. 1839-1850
-
-
Van Hul, N.1
Lanthier, N.2
Espanol Suner, R.3
Abarca Quinones, J.4
van Rooijen, N.5
Leclercq, I.6
-
24
-
-
36549013178
-
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
-
Schmitz KJ, Wohlschlaeger J, Lang H, Sotiropoulos GC, Malago M, Steveling K, et al. Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol 2008;48:83-90.
-
(2008)
J Hepatol
, vol.48
, pp. 83-90
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Lang, H.3
Sotiropoulos, G.C.4
Malago, M.5
Steveling, K.6
-
25
-
-
84859033221
-
Gene deletions and amplifications in human hepatocellular carcinomas: correlation with hepatocyte growth regulation
-
Nalesnik MA, Tseng G, Ding Y, Xiang GS, Zheng ZL, Yu Y, et al. Gene deletions and amplifications in human hepatocellular carcinomas: correlation with hepatocyte growth regulation. Am J Pathol 2012;180:1495-1508.
-
(2012)
Am J Pathol
, vol.180
, pp. 1495-1508
-
-
Nalesnik, M.A.1
Tseng, G.2
Ding, Y.3
Xiang, G.S.4
Zheng, Z.L.5
Yu, Y.6
-
26
-
-
79959263369
-
MAPK/ERK and Wnt/beta-Catenin pathways are synergistically involved in proliferation of Sca-1 positive hepatic progenitor cells
-
Jin C, Samuelson L, Cui CB, Sun Y, Gerber DA. MAPK/ERK and Wnt/beta-Catenin pathways are synergistically involved in proliferation of Sca-1 positive hepatic progenitor cells. Biochem Biophys Res Commun 2011;409:803-807.
-
(2011)
Biochem Biophys Res Commun
, vol.409
, pp. 803-807
-
-
Jin, C.1
Samuelson, L.2
Cui, C.B.3
Sun, Y.4
Gerber, D.A.5
-
27
-
-
31044455375
-
JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells
-
Li DQ, Luo L, Chen Z, Kim HS, Song XJ, Pflugfelder SC. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res 2006;82:588-596.
-
(2006)
Exp Eye Res
, vol.82
, pp. 588-596
-
-
Li, D.Q.1
Luo, L.2
Chen, Z.3
Kim, H.S.4
Song, X.J.5
Pflugfelder, S.C.6
-
28
-
-
79952298241
-
Liver stem/progenitor cells: their characteristics and regulatory mechanisms
-
Tanaka M, Itoh T, Tanimizu N, Miyajima A. Liver stem/progenitor cells: their characteristics and regulatory mechanisms. J Biochem 2011;149:231-239.
-
(2011)
J Biochem
, vol.149
, pp. 231-239
-
-
Tanaka, M.1
Itoh, T.2
Tanimizu, N.3
Miyajima, A.4
-
29
-
-
84864773126
-
Cholangiocarcinomas can originate from hepatocytes in mice
-
Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, et al. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest 2012;122:2911-2915.
-
(2012)
J Clin Invest
, vol.122
, pp. 2911-2915
-
-
Fan, B.1
Malato, Y.2
Calvisi, D.F.3
Naqvi, S.4
Razumilava, N.5
Ribback, S.6
-
30
-
-
84868625552
-
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes
-
Sekiya S, Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest 2012;122:3914-3918.
-
(2012)
J Clin Invest
, vol.122
, pp. 3914-3918
-
-
Sekiya, S.1
Suzuki, A.2
-
31
-
-
0141594641
-
The origin and liver repopulating capacity of murine oval cells
-
Wang X, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A 2003;100:11881-11888.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 11881-11888
-
-
Wang, X.1
Foster, M.2
Al-Dhalimy, M.3
Lagasse, E.4
Finegold, M.5
Grompe, M.6
-
32
-
-
33748060933
-
Abnormal expression of HSP gp96 associated with HBV replication in human hepatocellular carcinoma
-
Yao DF, Wu XH, Su XQ, Yao M, Wu W, Qiu LW, et al. Abnormal expression of HSP gp96 associated with HBV replication in human hepatocellular carcinoma. Hepatobil Pancreat Dis Int 2006;5:381-386.
-
(2006)
Hepatobil Pancreat Dis Int
, vol.5
, pp. 381-386
-
-
Yao, D.F.1
Wu, X.H.2
Su, X.Q.3
Yao, M.4
Wu, W.5
Qiu, L.W.6
-
33
-
-
33751193479
-
Glucose regulated proteins in cancer progression, drug resistance and immunotherapy
-
Fu Y, Lee AS. Glucose regulated proteins in cancer progression, drug resistance and immunotherapy. Cancer Biol Ther 2006;5:741-744.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 741-744
-
-
Fu, Y.1
Lee, A.S.2
-
34
-
-
0033214088
-
2+-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis
-
2+-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis. J Biol Chem 1999;274:28476-28483.
-
(1999)
J Biol Chem
, vol.274
, pp. 28476-28483
-
-
Reddy, R.K.1
Lu, J.2
Lee, A.S.3
|