G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons

Nature

Volumn 520, Issue 7545, 2015, Pages 94-98

  Ghamari Langroudi, Masoud ^a   Digby, Gregory J ^a   Sebag, Julien A ^a   Millhauser, Glenn L ^b   Palomino, Rafael ^b   Matthews, Robert ^a   Gillyard, Taneisha ^a,c   Panaro, Brandon L ^a   Tough, Iain R ^d   Cox, Helen M ^d   Denton, Jerod S ^a,e   Cone, Roger D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MEHARRY MEDICAL COLLEGE   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR7.1; MELANOCORTIN 4 RECEPTOR; UNCLASSIFIED DRUG; AGRP PROTEIN, MOUSE; KIR7.1 CHANNEL; LIGAND; MC4R PROTEIN, MOUSE; MELANOCORTIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

AMINO ACID; HOMEOSTASIS; LIGAND; NEUROLOGY; POTASSIUM; PROTEIN; SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; FEMALE; GENE DOSAGE; GENE EXPRESSION REGULATION; HEK293 CELL LINE; HOMEOSTASIS; HUMAN; HUMAN CELL; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ACTION POTENTIAL; ANIMAL; CYTOLOGY; EATING; ENERGY METABOLISM; GENETICS; METABOLISM; NERVE CELL;

AGOUTI; MUS;

ACTION POTENTIALS; AGOUTI-RELATED PROTEIN; ALPHA-MSH; ANIMALS; EATING; ENERGY METABOLISM; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HEK293 CELLS; HOMEOSTASIS; HUMANS; LIGANDS; MALE; MELANOCORTINS; MICE; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTOR, MELANOCORTIN, TYPE 4; SIGNAL TRANSDUCTION;

EID: 84926393022     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14051     Document Type: Article

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