메뉴 건너뛰기




Volumn 37, Issue 1, 2015, Pages 3-8

Biomarkers and staging of bipolar disorder: A systematic review;Dos biomarcadores ao estadiamento do transtorno bipolar: Uma revisão sistemática

Author keywords

Bipolar disorder; Inflammation; Neuroimaging changes; Neurotrophic factors; Oxidative stress; Staging

Indexed keywords

3 NITROTYROSINE; ACETYLCYSTEINE; BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; C REACTIVE PROTEIN; CYTOKINE; DOPAMINE; GLUTAMIC ACID; GLYCOPROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LITHIUM; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; NITRIC OXIDE; SEROTONIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84926383076     PISSN: 22376089     EISSN: None     Source Type: Journal    
DOI: 10.1590/2237-6089-2014-0002     Document Type: Review
Times cited : (36)

References (101)
  • 1
    • 79952327729 scopus 로고    scopus 로고
    • Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative
    • Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry. 2011;68:241-51.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 241-251
    • Merikangas, K.R.1    Jin, R.2    He, J.P.3    Kessler, R.C.4    Lee, S.5    Sampson, N.A.6
  • 3
    • 0036280163 scopus 로고    scopus 로고
    • Mortality of patients with mood disorders: Follow-up over 34-38 years
    • Angst F, Stassen HH, Clayton PJ, Angst J. Mortality of patients with mood disorders: follow-up over 34-38 years. J Affect Disord. 2002;68:167-81.
    • (2002) J Affect Disord , vol.68 , pp. 167-181
    • Angst, F.1    Stassen, H.H.2    Clayton, P.J.3    Angst, J.4
  • 4
    • 18944369872 scopus 로고    scopus 로고
    • The increasing medical burden in bipolar disorder
    • Kupfer DJ. The increasing medical burden in bipolar disorder. JAMA. 2005;293:2528-30.
    • (2005) JAMA , vol.293 , pp. 2528-2530
    • Kupfer, D.J.1
  • 5
    • 84865476334 scopus 로고    scopus 로고
    • Can bipolar disorder be viewed as a multi-system inflammatory disease? J affect disord
    • Leboyer M, Soreca I, Scott J, Frye M, Henry C, Tamouza R, et al. Can bipolar disorder be viewed as a multi-system inflammatory disease? J Affect Disord. 2012;141:1-10. Epub 2012 Apr 11.
    • (2012) Epub , vol.141 , pp. 1-10
    • Leboyer, M.1    Soreca, I.2    Scott, J.3    Frye, M.4    Henry, C.5    Tamouza, R.6
  • 7
    • 84859856121 scopus 로고    scopus 로고
    • Neurobiological correlates of illness progression in the recurrent affective disorders. J psychiatr res
    • Post RM, Fleming J, Kapczinski F. Neurobiological correlates of illness progression in the recurrent affective disorders. J Psychiatr Res. 2012;46:561-73. Epub 2012 Mar 23.
    • (2012) Epub , vol.46 , pp. 561-573
    • Post, R.M.1    Fleming, J.2    Kapczinski, F.3
  • 8
    • 78649938042 scopus 로고    scopus 로고
    • Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors
    • Berk M, Kapczinski F, Andreazza AC, Dean OM, Giorlando F, Maes M, et al. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci Biobehav Rev. 2011;35:804-17. Epub 2010 Oct 8.
    • (2010) Neurosci Biobehav Rev , vol.35 , pp. 804-817
    • Berk, M.1    Kapczinski, F.2    Andreazza, A.C.3    Dean, O.M.4    Giorlando, F.5    Maes, M.6
  • 10
    • 78049274826 scopus 로고    scopus 로고
    • Mechanisms of illness progression in the recurrent affective disorders
    • Post RM. Mechanisms of illness progression in the recurrent affective disorders. Neurotox Res. 2010;18:256-71.
    • (2010) Neurotox Res , vol.18 , pp. 256-271
    • Post, R.M.1
  • 11
    • 32244443552 scopus 로고    scopus 로고
    • Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar i disorder based on number of previous manic or mixed episodes
    • Ketter TA, Houston JP, Adams DH, Risser RC, Meyers AL, Williamson DJ, et al. Differential efficacy of olanzapine and lithium in preventing manic or mixed recurrence in patients with bipolar I disorder based on number of previous manic or mixed episodes. J Clin Psychiatry. 2006;67:95-101.
    • (2006) J Clin Psychiatry , vol.67 , pp. 95-101
    • Ketter, T.A.1    Houston, J.P.2    Adams, D.H.3    Risser, R.C.4    Meyers, A.L.5    Williamson, D.J.6
  • 12
    • 0032866814 scopus 로고    scopus 로고
    • Differential effect of number of previous episodes of affective disorder on response to lithium or divalproex in acute mania
    • Swann AC, Bowden CL, Calabrese JR, Dilsaver SC, Morris DD. Differential effect of number of previous episodes of affective disorder on response to lithium or divalproex in acute mania. Am J Psychiatry. 1999;156:1264-6.
    • (1999) Am J Psychiatry , vol.156 , pp. 1264-1266
    • Swann, A.C.1    Bowden, C.L.2    Calabrese, J.R.3    Dilsaver, S.C.4    Morris, D.D.5
  • 13
    • 33645676093 scopus 로고    scopus 로고
    • Cognitive-behavioural therapy for severe and recurrent bipolar disorders: Randomised controlled trial
    • Scott J1, Paykel E, Morriss R, Bentall R, Kinderman P, Johnson T, et al. Cognitive-behavioural therapy for severe and recurrent bipolar disorders: randomised controlled trial. Br J Psychiatry. 2006;188:313-20.
    • (2006) Br J Psychiatry , vol.188 , pp. 313-320
    • J1, S.1    Paykel, E.2    Morriss, R.3    Bentall, R.4    Kinderman, P.5    Johnson, T.6
  • 16
    • 67649205987 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. Late-stage bipolar disorder
    • Kauer-Sant’Anna M, Kapczinski F, Andreazza AC, Bond DJ, Lam RW, Young LT, et al. Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder. Int J Neuropsychopharmacol. 2009;12:447-58. Epub 2008. Sep 4
    • (2008) Int J Neuropsychopharmacol , vol.2009 , Issue.12 , pp. 447-458
    • Kauer-Sant’anna, M.1    Kapczinski, F.2    Andreazza, A.C.3    Bond, D.J.4    Lam, R.W.5    Young, L.T.6
  • 17
    • 79751530061 scopus 로고    scopus 로고
    • Staging bipolar disorder. Neurotox res
    • Vieta E, Reinares M, Rosa AR. Staging bipolar disorder. Neurotox Res. 2011;19:279-85. Epub 2010. May 12
    • (2010) Epub , vol.2011 , Issue.19 , pp. 279-285
    • Vieta, E.1    Reinares, M.2    Rosa, A.R.3
  • 18
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther. 2001;69:89-95.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 20
    • 70349664473 scopus 로고    scopus 로고
    • How-to guide on biomarkers: Biomarker definitions, validation and applications with examples from cardiovascular disease
    • Puntmann VO. How-to guide on biomarkers: biomarker definitions, validation and applications with examples from cardiovascular disease. Postgrad Med J. 2009;85:538-45.
    • (2009) Postgrad Med J , vol.85 , pp. 538-545
    • Puntmann, V.O.1
  • 21
    • 40349106019 scopus 로고    scopus 로고
    • The utility of biomarker discovery approaches for the detection of disease mechanisms in psychiatric disorders
    • Epub 2008 Jan 14
    • Schwarz E, Bahn S. The utility of biomarker discovery approaches for the detection of disease mechanisms in psychiatric disorders. Br J Pharmacol. 2008;153(Suppl 1):S133-6. Epub 2008 Jan 14.
    • (2008) Br J Pharmacol , vol.153 , pp. S133-S136
    • Schwarz, E.1    Bahn, S.2
  • 22
    • 84880530104 scopus 로고    scopus 로고
    • Biomarkers in bipolar disorder: A positional paper from the international society for bipolar disorders biomarkers task force
    • Epub 2013 Feb 14
    • Frey BN, Andreazza AC, Houenou J, Jamain S, Goldstein BI, Frye MA, et al. Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force. Aust N Z J Psychiatry. 2013;47:321-32. Epub 2013 Feb 14.
    • (2013) Aust N Z J Psychiatry , vol.47 , pp. 321-332
    • Frey, B.N.1    Andreazza, A.C.2    Houenou, J.3    Jamain, S.4    Goldstein, B.I.5    Frye, M.A.6
  • 24
    • 0036842774 scopus 로고    scopus 로고
    • Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder
    • Strakowski SM, DelBello MP, Zimmerman ME, Getz GE, Mills NP, Ret J, et al. Ventricular and periventricular structural volumes in first- versus multiple-episode bipolar disorder. Am J Psychiatry. 2002;159:1841-7.
    • (2002) Am J Psychiatry , vol.159 , pp. 1841-1847
    • Strakowski, S.M.1    Delbello, M.P.2    Zimmerman, M.E.3    Getz, G.E.4    Mills, N.P.5    Ret, J.6
  • 27
    • 33644817037 scopus 로고    scopus 로고
    • Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: A cross-sectional study
    • Epub 2006 Jan 18
    • Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, et al. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol Psychiatry 2006;59:611-8. Epub 2006 Jan 18.
    • (2006) Biol Psychiatry , vol.59 , pp. 611-618
    • Blumberg, H.P.1    Krystal, J.H.2    Bansal, R.3    Martin, A.4    Dziura, J.5    Durkin, K.6
  • 29
    • 0036102198 scopus 로고    scopus 로고
    • Volumetric brain imaging findings in mood disorders
    • Beyer JL, Krishnam KR. Volumetric brain imaging findings in mood disorders. Bipolar Disord. 2002;4:89-104.
    • (2002) Bipolar Disord , vol.4 , pp. 89-104
    • Beyer, J.L.1    Krishnam, K.R.2
  • 31
    • 1342290288 scopus 로고    scopus 로고
    • Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder
    • DelBello MP, Zimmerman ME, Mills NP, Getz GE, Strakowski SM. Magnetic resonance imaging analysis of amygdala and other subcortical brain regions in adolescents with bipolar disorder. Bipolar Disord. 2004;6:43-52.
    • (2004) Bipolar Disord , vol.6 , pp. 43-52
    • Delbello, M.P.1    Zimmerman, M.E.2    Mills, N.P.3    Getz, G.E.4    Strakowski, S.M.5
  • 32
    • 79151472847 scopus 로고    scopus 로고
    • Structural magnetic resonance imaging in bipolar disorder: An international collaborative mega-analysis of individual adult patient data
    • Epub 2010 Oct 27
    • Hallahan B, Newell J, Soares JC, Brambilla P, Strakowski SM, Fleck DE, et al. Structural magnetic resonance imaging in bipolar disorder: an international collaborative mega-analysis of individual adult patient data. Biol Psychiatry. 2011;69:326-35. Epub 2010 Oct 27.
    • (2011) Biol Psychiatry , vol.69 , pp. 326-335
    • Hallahan, B.1    Newell, J.2    Soares, J.C.3    Brambilla, P.4    Strakowski, S.M.5    Fleck, D.E.6
  • 33
    • 0031851674 scopus 로고    scopus 로고
    • Amygdala enlargement in bipolar disorder and hippocampal reduction in schizophrenia: An mri study demonstrating neuroanatomic specificity
    • Altshuler LL, Bartzokis G, Grieder T, Curran J, Mintz J. Amygdala enlargement in bipolar disorder and hippocampal reduction in schizophrenia: an MRI study demonstrating neuroanatomic specificity. Arch Gen Psychiatry. 1998;55:663-4.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 663-664
    • Altshuler, L.L.1    Bartzokis, G.2    Grieder, T.3    Curran, J.4    Mintz, J.5
  • 37
    • 38049108182 scopus 로고    scopus 로고
    • Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium
    • Foland LC, Altshuler LL, Sugar CA, Lee AD, Leow AD, Townsend J, et al. Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium. Neuroreport. 2008;19:221-4.
    • (2008) Neuroreport , vol.19 , pp. 221-224
    • Foland, L.C.1    Altshuler, L.L.2    Sugar, C.A.3    Lee, A.D.4    Leow, A.D.5    Townsend, J.6
  • 38
    • 50949102049 scopus 로고    scopus 로고
    • Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder
    • Kempton MJ, Geddes JR, Ettinger U, Williams SC, Grasby PM. Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder. Arch Gen Psychiatry. 2008;65:1017-32.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 1017-1032
    • Kempton, M.J.1    Geddes, J.R.2    Ettinger, U.3    Williams, S.C.4    Grasby, P.M.5
  • 39
    • 28444470910 scopus 로고    scopus 로고
    • T2 hyperintensities in bipolar patients and their healthy siblings
    • Gulseren S, Gurcan M, Gulseren L, Gelal F, Erol A. T2 hyperintensities in bipolar patients and their healthy siblings. Arch Med Res. 2006;37:79-85.
    • (2006) Arch Med Res , vol.37 , pp. 79-85
    • Gulseren, S.1    Gurcan, M.2    Gulseren, L.3    Gelal, F.4    Erol, A.5
  • 40
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat Rev Neurosci. 2005;6:603-14.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 41
    • 34548130153 scopus 로고    scopus 로고
    • Role of bdnf in bipolar and unipolar disorder: Clinical and theoretical implications
    • Epub 2007 Jan 18
    • Post RM. Role of BDNF in bipolar and unipolar disorder: clinical and theoretical implications. J Psychiatr Res. 2007;41:979-90. Epub 2007 Jan 18.
    • (2007) J Psychiatr Res , vol.41 , pp. 979-990
    • Post, R.M.1
  • 42
    • 84861396349 scopus 로고    scopus 로고
    • Kapczinski f. [peripheral markers and the pathophysiology of bipolar disorder]
    • Magalhães PV, Fries GR, Kapczinski F. [Peripheral markers and the pathophysiology of bipolar disorder]. Rev Psiquiatr Clin. 2012;39:60-7.
    • (2012) Rev Psiquiatr Clin , vol.39 , pp. 60-67
    • Magalhães, P.V.1    Fries, G.R.2
  • 44
    • 78650758486 scopus 로고    scopus 로고
    • Circulating levels of brain-derived neurotrophic factor: Correlation with mood, cognition and motor function
    • Teixeira AL, Barbosa IG, Diniz BS, Kummer A. Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function. Biomark Med 2010;4:871-87.
    • (2010) Biomark Med , vol.4 , pp. 871-887
    • Teixeira, A.L.1    Barbosa, I.G.2    Diniz, B.S.3    Kummer, A.4
  • 45
    • 79958747390 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis
    • Fernandes BS, Gama CS, Ceresér KM, Yatham LN, Fries GR, Colpo G, et al. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. J Psychiatr Res. 2011;45:995-1004.
    • (2011) J Psychiatr Res , vol.45 , pp. 995-1004
    • Fernandes, B.S.1    Gama, C.S.2    Ceresér, K.M.3    Yatham, L.N.4    Fries, G.R.5    Colpo, G.6
  • 46
    • 70350341183 scopus 로고    scopus 로고
    • State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: A meta-analytic study
    • Epub 2009 Sep 26
    • Lin PY. State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: a meta-analytic study. Neurosci Lett. 2009;466:139-43. Epub 2009 Sep 26.
    • (2009) Neurosci Lett , vol.466 , pp. 139-143
    • Lin, P.Y.1
  • 47
    • 70349780607 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis
    • Epub 2009 Jun 6
    • Fernandes BS, Gama CS, Kauer-Sant’Anna M, Lobato MI, Belmonte-de-Abreu P, Kapczinski F. Serum brain-derived neurotrophic factor in bipolar and unipolar depression: a potential adjunctive tool for differential diagnosis. J Psychiatr Res. 2009;43:1200-4. Epub 2009 Jun 6.
    • (2009) J Psychiatr Res , vol.43 , pp. 1200-1204
    • Fernandes, B.S.1    Gama, C.S.2    Kauer-Sant’anna, M.3    Lobato, M.I.4    Belmonte-De-Abreu, P.5    Kapczinski, F.6
  • 49
    • 33646376946 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes
    • Epub 2006 Feb 9
    • Cunha AB, Frey BN, Andreazza AC, Goi JD, Rosa AR, Gonçalves CA, et al. Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes. Neurosci Lett. 2006;398:215-9. Epub 2006 Feb 9x.
    • (2006) Neurosci Lett , vol.398 , pp. 215-219
    • Cunha, A.B.1    Frey, B.N.2    Andreazza, A.C.3    Goi, J.D.4    Rosa, A.R.5    Gonçalves, C.A.6
  • 50
    • 79551638797 scopus 로고    scopus 로고
    • The role of bdnf as a mediator of neuroplasticity in bipolar disorder
    • Grande I, Fries GR, Kunz M, Kapczinski F. The role of BDNF as a mediator of neuroplasticity in bipolar disorder. Psychiatry Investig. 2010;7:243-50.
    • (2010) Psychiatry Investig , vol.7 , pp. 243-250
    • Grande, I.1    Fries, G.R.2    Kunz, M.3    Kapczinski, F.4
  • 52
    • 60249084435 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor serum levels before and after treatment for acute mania
    • Epub 2009 Jan 15
    • Tramontina JF, Andreazza AC, Kauer-Sant’anna M, Stertz L, Goi J, Chiarani F, et al. Brain-derived neurotrophic factor serum levels before and after treatment for acute mania. Neurosci Lett. 2009;452:111-3. Epub 2009 Jan 15.
    • (2009) Neurosci Lett , vol.452 , pp. 111-113
    • Tramontina, J.F.1    Andreazza, A.C.2    Kauer-Sant’anna, M.3    Stertz, L.4    Goi, J.5    Chiarani, F.6
  • 54
    • 77953501147 scopus 로고    scopus 로고
    • Excellent lithium responders have normal cognitive functions and plasma bdnf levels
    • Epub 2010 Apr 15
    • JK1 Rybakowski, Suwalska A. Excellent lithium responders have normal cognitive functions and plasma BDNF levels. Int J Neuropsychopharmacol. 2010;13:617-22. Epub 2010 Apr 15.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 617-622
    • Rybakowski, J.K.1    Suwalska, A.2
  • 55
    • 0036347948 scopus 로고    scopus 로고
    • Family-based association study of 76 candidate genes in bipolar disorder: Bdnf is a potential risk locus. Brain-derived neutrophic factor
    • Sklar P, Gabriel SB, McInnis MG, Bennett P, Lim Y-, Tsan G, et al. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry. 2002;7:579-93.
    • (2002) Mol Psychiatry , vol.7 , pp. 579-593
    • Sklar, P.1    Gabriel, S.B.2    McInnis, M.G.3    Bennett, P.4    Lim, Y.5    Tsan, G.6
  • 56
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study
    • Epub 2002 Aug 2
    • Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet. 2002;71:651-5. Epub 2002 Aug 2.
    • (2002) Am J Hum Genet , vol.71 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    Macciardi, F.5    Kennedy, J.L.6
  • 57
    • 4444322215 scopus 로고    scopus 로고
    • Linkage disequilibrium of the brain-derived neurotrophic factor val66met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    • Geller B, Badner JA, Tillman R, Christian SL, Bolhofner K, Cook EH Jr. Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry. 2004;161:1698-700.
    • (2004) Am J Psychiatry , vol.161 , pp. 1698-1700
    • Geller, B.1    Badner, J.A.2    Tillman, R.3    Christian, S.L.4    Bolhofner, K.5    Cook, E.H.6
  • 58
    • 15044352385 scopus 로고    scopus 로고
    • Association analysis of brainderived neurotrophic factor (bdnf) gene val66met polymorphism in schizophrenia and bipolar affective disorder
    • Skibinska M, Hauser J, Czerski PM, Leszczynska-Rodziewicz A, Kosmowska M, Kapelski P, et al. Association analysis of brainderived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder. World J Biol Psychiatry. 2004;5:215-20.
    • (2004) World J Biol Psychiatry , vol.5 , pp. 215-220
    • Skibinska, M.1    Hauser, J.2    Czerski, P.M.3    Leszczynska-Rodziewicz, A.4    Kosmowska, M.5    Kapelski, P.6
  • 59
    • 27644551826 scopus 로고    scopus 로고
    • Confirmation of association between the val66met polymorphism in the brain-derived neurotrophic factor (bdnf) gene and bipolar i disorder
    • Lohoff FW, Sander T, Ferraro TN, Dahl JP, Gallinat J, Berrettini WH. Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder. Am J Med Genet B Neuropsychiatr Genet. 2005;139B:51-3.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.139B , pp. 51-53
    • Lohoff, F.W.1    Sander, T.2    Ferraro, T.N.3    Dahl, J.P.4    Gallinat, J.5    Berrettini, W.H.6
  • 60
    • 29644432625 scopus 로고    scopus 로고
    • Genetic variation of brain-derived neurotrophic factor (bdnf) in bipolar disorder: Case-control study of over 3000 individuals from the uk
    • Green EK, Raybould R, Macgregor S, Hyde S, Young AH, O’Donovan MC, et al. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. Br J Psychiatry. 2006;188:21-5.
    • (2006) Br J Psychiatry , vol.188 , pp. 21-25
    • Green, E.K.1    Raybould, R.2    Macgregor, S.3    Hyde, S.4    Young, A.H.5    O’Donovan, M.C.6
  • 61
    • 7644223101 scopus 로고    scopus 로고
    • Association study of brain-derived neurotrophic factor in adults with a history of childhood onset mood disorder
    • Strauss J, Barr CL, George CJ, King N, Shaikh S, Devlin B, et al. Association study of brain-derived neurotrophic factor in adults with a history of childhood onset mood disorder. Am J Med Genet B Neuropsychiatr Genet. 2004;131B:16-9.
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.131B , pp. 16-19
    • Strauss, J.1    Barr, C.L.2    George, C.J.3    King, N.4    Shaikh, S.5    Devlin, B.6
  • 62
    • 0037472372 scopus 로고    scopus 로고
    • Association study of the brain-derived neurotrophic factor (bdnf) gene with bipolar disorder
    • Nakata K, Ujike H, Sakai A, Uchida N, Nomura A, Imamura T, et al. Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder. Neurosci Lett. 2003;337:17-20.
    • (2003) Neurosci Lett , vol.337 , pp. 17-20
    • Nakata, K.1    Ujike, H.2    Sakai, A.3    Uchida, N.4    Nomura, A.5    Imamura, T.6
  • 63
    • 0347380124 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior
    • Hong CJ, Huo SJ, Yen FC, Tung CL, Pan GM, Tsai SJ. Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior. Neuropsychobiology. 2003;48:186-9.
    • (2003) Neuropsychobiology , vol.48 , pp. 186-189
    • Hong, C.J.1    Huo, S.J.2    Yen, F.C.3    Tung, C.L.4    Pan, G.M.5    Tsai, S.J.6
  • 64
    • 4444314095 scopus 로고    scopus 로고
    • No association between the val66met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a japanese population: A multicenter study
    • Kunugi H, Iijima Y, Tatsumi M, Yoshida M, Hashimoto R, Kato T, et al. No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study. Biol Psychiatry. 2004;56:376-8.
    • (2004) Biol Psychiatry , vol.56 , pp. 376-378
    • Kunugi, H.1    Iijima, Y.2    Tatsumi, M.3    Yoshida, M.4    Hashimoto, R.5    Kato, T.6
  • 66
    • 33847628372 scopus 로고    scopus 로고
    • Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder
    • Epub 2007 Jan 17
    • Walz JC, Andreazza AC, Frey BN, Cacilhas AA, Ceresér KM, Cunha AB, et al. Serum neurotrophin-3 is increased during manic and depressive episodes in bipolar disorder. Neurosci Lett. 2007;415:87-9.Epub 2007 Jan 17.
    • (2007) Neurosci Lett , vol.415 , pp. 87-89
    • Walz, J.C.1    Andreazza, A.C.2    Frey, B.N.3    Cacilhas, A.A.4    Ceresér, K.M.5    Cunha, A.B.6
  • 67
    • 77953288705 scopus 로고    scopus 로고
    • Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes
    • Epub 2010 Jan 8
    • Fernandes BS, Gama CS, Walz JC, Ceresér KM, Fries GR, Colpo G, et al. Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes. J Psychiatr Res. 2010;44:561-5. Epub 2010 Jan 8.
    • (2010) J Psychiatr Res , vol.44 , pp. 561-565
    • Fernandes, B.S.1    Gama, C.S.2    Walz, J.C.3    Ceresér, K.M.4    Fries, G.R.5    Colpo, G.6
  • 69
  • 70
    • 35948958993 scopus 로고    scopus 로고
    • Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder
    • Epub 2007 Apr 16
    • Kim YK, Jung HG, Myint AM, Kim H, Park SH. Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder. J Affect Disord. 2007;104:91-5. Epub 2007 Apr 16.
    • (2007) J Affect Disord , vol.104 , pp. 91-95
    • Kim, Y.K.1    Jung, H.G.2    Myint, A.M.3    Kim, H.4    Park, S.H.5
  • 74
    • 34247490138 scopus 로고    scopus 로고
    • Elevated serum levels of c-reactive protein are associated with mania symptoms in outpatients with bipolar disorder
    • Epub 2007 Mar 6
    • Dickerson F, Stallings C, Origoni A, Boronow J, Yolken R. Elevated serum levels of C-reactive protein are associated with mania symptoms in outpatients with bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:952-5.Epub 2007 Mar 6.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 952-955
    • Dickerson, F.1    Stallings, C.2    Origoni, A.3    Boronow, J.4    Yolken, R.5
  • 75
    • 79960242549 scopus 로고    scopus 로고
    • Brain inflammation is induced by co-morbidities and risk factors for stroke
    • Epub 2011 Feb 26
    • Drake C, Boutin H, Jones MS, Denes A, McColl BW, Selvarajah JR, et al. Brain inflammation is induced by co-morbidities and risk factors for stroke. Brain Behav Immun. 2011;25:1113-22. Epub 2011 Feb 26.
    • (2011) Brain Behav Immun , vol.25 , pp. 1113-1122
    • Drake, C.1    Boutin, H.2    Jones, M.S.3    Denes, A.4    McColl, B.W.5    Selvarajah, J.R.6
  • 76
    • 72849153748 scopus 로고    scopus 로고
    • Medical comorbidity among youth diagnosed with bipolar disorder in the united states
    • Epub 2009 Sep 8
    • Evans-Lacko SE, Zeber JE, Gonzalez JM, Olvera RL. Medical comorbidity among youth diagnosed with bipolar disorder in the United States. J Clin Psychiatry. 2009:70:1461-6. Epub 2009 Sep 8.
    • (2009) J Clin Psychiatry , vol.70 , pp. 1461-1466
    • Evans-Lacko, S.E.1    Zeber, J.E.2    Gonzalez, J.M.3    Olvera, R.L.4
  • 77
    • 70349562518 scopus 로고    scopus 로고
    • Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: A systematic review of the literature
    • Epub 2009 Jun 2
    • Goldstein BI, Kemp DE, Soczynska JK, McIntyre RS. Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature. J Clin Psychiatry. 2009;70:1078-90. Epub 2009 Jun 2.
    • (2009) J Clin Psychiatry , vol.70 , pp. 1078-1090
    • Goldstein, B.I.1    Kemp, D.E.2    Soczynska, J.K.3    McIntyre, R.S.4
  • 79
    • 84856211599 scopus 로고    scopus 로고
    • Reactive oxygen species and ischemic cerebrovascular disease
    • Epub 2011 Nov 22
    • Olmez I, Ozyurt H. Reactive oxygen species and ischemic cerebrovascular disease. Neurochem Int. 2012;60:208-12. Epub 2011 Nov 22.
    • (2012) Neurochem Int , vol.60 , pp. 208-212
    • Olmez, I.1    Ozyurt, H.2
  • 84
    • 70149115047 scopus 로고    scopus 로고
    • Gonçalves ca, et al. 3-nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder
    • Andreazza AC, Kapczinski F, Kauer-Sant’Anna M, Walz JC, Bond DJ, Gonçalves CA, et al. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J Psychiatry Neurosci. 2009;34:263-71.
    • (2009) J Psychiatry Neurosci , vol.34 , pp. 263-271
    • Andreazza, A.C.1    Kapczinski, F.2    Kauer-Sant’anna, M.3    Walz, J.C.4    Bond, D.J.5
  • 85
    • 51349132292 scopus 로고    scopus 로고
    • Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia
    • Epub 2008 Jul 6
    • Kunz M, Gama CS, Andreazza AC, Salvador M, Ceresér KM, Gomes FA, et al. Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1677-81. Epub 2008 Jul 6.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 1677-1681
    • Kunz, M.1    Gama, C.S.2    Andreazza, A.C.3    Salvador, M.4    Ceresér, K.M.5    Gomes, F.A.6
  • 86
    • 34250318164 scopus 로고    scopus 로고
    • Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects
    • Epub 2007 May 22
    • Machado-Vieira R, Andreazza AC, Viale CI, Zanatto V, Cereser V Jr, da Silva Vargas R, et al. Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects. Neurosci Lett. 2007;421:33-6. Epub 2007 May 22.
    • (2007) Neurosci Lett , vol.421 , pp. 33-36
    • Machado-Vieira, R.1    Andreazza, A.C.2    Viale, C.I.3    Zanatto, V.4    Cereser, V.5    Da Silva Vargas, R.6
  • 89
    • 80055021253 scopus 로고    scopus 로고
    • The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar ii disorder
    • Epub 2011 Aug 30
    • Elvsåshagen T, Vera E, Bøen E, Bratlie J, Andreassen OA, Josefsen D, et al. The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder. J Affect Disord. 2011;135:43-50. Epub 2011 Aug 30.
    • (2011) J Affect Disord , vol.135 , pp. 43-50
    • Elvsåshagen, T.1    Vera, E.2    Bøen, E.3    Bratlie, J.4    Andreassen, O.A.5    Josefsen, D.6
  • 90
    • 0036236630 scopus 로고    scopus 로고
    • Replicative aging, telomeres, and oxidative stress
    • Saretzki, G, Von-Zglinicki T. Replicative aging, telomeres, and oxidative stress. Ann N Y Acad Sci. 2002;959:24-9.
    • (2002) Ann N Y Acad Sci , vol.959 , pp. 24-29
    • Saretzki, G.1    Von-Zglinicki, T.2
  • 91
    • 33747876876 scopus 로고    scopus 로고
    • Telomere shortening and mood disorders: Preliminary support for a chronic stress model of accelerated aging
    • Epub 2006 Apr 11
    • NM1 Simon, Smoller JW, McNamara KL, Maser RS, Zalta AK, Pollack MH, et al. Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. Biol Psychiatry. 2006;60:432-5. Epub 2006 Apr 11.
    • (2006) Biol Psychiatry , vol.60 , pp. 432-435
    • Simon, N.M.1    Smoller, J.W.2    McNamara, K.L.3    Maser, R.S.4    Zalta, A.K.5    Pollack, M.H.6
  • 92
    • 49749109893 scopus 로고    scopus 로고
    • N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial
    • Epub 2008 Jun 5
    • Berk M, Copolov DL, Dean O, Lu K, Jeavons S, Schapkaitz I, et al. N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial. Biol Psychiatry. 2008;64:468-75. Epub 2008 Jun 5.
    • (2008) Biol Psychiatry , vol.64 , pp. 468-475
    • Berk, M.1    Copolov, D.L.2    Dean, O.3    Lu, K.4    Jeavons, S.5    Schapkaitz, I.6
  • 98
    • 34249299022 scopus 로고    scopus 로고
    • The potential utility of a staging model as a course specifier: A bipolar disorder perspective
    • Epub 2007 Apr 11
    • Berk M, Hallam KT, McGorry PD. The potential utility of a staging model as a course specifier: a bipolar disorder perspective. J Affect Disord. 2007;100:279-81. Epub 2007 Apr 11.
    • (2007) J Affect Disord , vol.100 , pp. 279-281
    • Berk, M.1    Hallam, K.T.2    McGorry, P.D.3
  • 99
    • 35748934486 scopus 로고    scopus 로고
    • Setting the stage: From prodrome to treatment resistance in bipolar disorder
    • Berk M, Conus P, Lucas N, Hallam K, Malhi GS, Dodd S, et al. Setting the stage: from prodrome to treatment resistance in bipolar disorder. Bipolar Disord. 2007;9:671-8.
    • (2007) Bipolar Disord , vol.9 , pp. 671-678
    • Berk, M.1    Conus, P.2    Lucas, N.3    Hallam, K.4    Malhi, G.S.5    Dodd, S.6
  • 101
    • 59649116613 scopus 로고    scopus 로고
    • Early intervention in bipolar disorders: Clinical, biochemical and neuroimaging imperatives
    • Berk M, Malhi GS, Hallam K, Gama CS, Dodd S, Andreazza AC, et al. Early intervention in bipolar disorders: clinical, biochemical and neuroimaging imperatives. J Affect Disord. 2009;114:1-13.
    • (2009) J Affect Disord , vol.114 , pp. 1-13
    • Berk, M.1    Malhi, G.S.2    Hallam, K.3    Gama, C.S.4    Dodd, S.5    Andreazza, A.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.